TEHRAN (FNA)- Findings of a new study revealed that compared to sophisticated indigestion drugs, starting treatment with antacids can result in similar effects but with lower costs.
While the majority of patients affected with new-onset dyspepsia are empirically treated with pricey proton pump inhibitors (PPIs), antacids and H2 receptor antagonists can effectively overcome the problem in the majority of these individuals.
According to a study published in The Lancet, antacids should be the first-line drugs in treating indigestion; more powerful drugs should be added thereafter if required.
Similar success was reported in individuals treated with PPIs and then worked down to antacids compared to patients whose regimen consisted of antacids, then H2-receptor antagonists and finally PPIs.
Considering their cost-effectiveness, scientists concluded that physicians should start treating indigestion and abdominal discomfort with antacids and then work up to PPIs if necessary.