Abdollah Mesbah, 55, and Keramat Aziz-zadeh, 39, started their journey in cooperation with Iran Cultural Heritage, Handicrafts and Tourism Organization and the United Nations Children's Fund (UNICEF) office in Tehran on October 2008.
The two adventurous Iranian cyclists started their journey from Iran and have pedaled to Malaysia and Singapore so far, the Islamic republic news agency reported.
They are going to pedal to the Philippines, China, Bangladesh, India and Pakistan.
"We want to bring a message of peace and friendship to as many people as possible." said Mesbah, a retired colonel from Tehran.
"We ride bicycles to bring our message to all commuters that the global environment is getting worse and we should help decrease global warming," added Aziz-zadeh, who owns a small restaurant in the town of Astara, northern Iran.
The two have undertaken cycling trips to promote peace for more than a decade. Last year, the pair pedaled to Russia and Azerbaijan.