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Health & Environmental Research Online (HERO)

Learn about the studies used in EPA's science assesssments Using the latest information science tools Public access to the scientific literature used for EPA science assessments HERO brings you the key studies EPA uses to inform its decisions
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The HERO Database

The Health and Environmental Research Online (HERO) database provides an easy way to view the scientific literature behind EPA science assessments.

The database includes more than 300,000 scientific articles from the peer-reviewed literature used by EPA to develop its Integrated Science Assessments (ISA) that feed into the NAAQS review. It also includes references and data from the Integrated Risk Information System (IRIS), a database that supports critical agency policymaking for chemical regulation. Risk assessments characterize the nature and magnitude of health risks to humans and the ecosystem from pollutants and chemicals in the environment.

HERO is an EVERGREEN database. This means that new studies are continuously added so scientists can keep abreast of new research. References are then sorted, classified and made available through HERO.

HERO is part of the open government directive to conduct business with transparency, participation, and collaboration. Every American has the right to know the data behind EPA's regulatory process. Through HERO, the public can participate in the decision-making process.


NAAQS Air Quality Assessments

Carbon Monoxide

View the studies used in the 2009 CO Integrated Science Assessment (ISA)

1/29/2010: EPA has released the final Integrated Science Assessment (ISA) for Carbon Monoxide (CO).
This is EPA's latest evaluation of the scientific literature on the potential human health and welfare effects associated with ambient exposures to CO. The development of this document is part of the Agency's periodic review of the national ambient air quality standards (NAAQS) for CO. The recently completed CO ISA and supplementary annexes, will provide the scientific basis to inform EPA decisions related to the review of the current CO NAAQS. Read the assessment

Particulate Matter

View the studies used in the 2009 Particulate Matter Integrated Science Assessment

12/15/09: EPA released the final Integrated Science Assessment (ISA) for Particulate Matter (PM). This is EPAs latest evaluation of the scientific literature on the potential human health and welfare effects associated with ambient exposures to PM. Read the assessment.

NOx-SOx Eco

View the studies used in the 2008 Integrated Science Assessment (ISA) for Oxides of Nitrogen and Sulfur - Ecological Criteria

12/12/08: This concise synthesis and evaluation of the most policy-relevant science and will ultimately provide the scientific bases for EPA's decision on retaining or revising the current secondary standards for NO 2 and SO 2 . Read the assessment.


IRIS Chemical Assessments

Chloroprene

View the studies used in the 2010 Toxicological Review of Chloroprene

9/30/10: Toxicological Review. Chloroprene (C4H5Cl) is a volatile, flammable liquid used primarily in the manufacture of polychloroprene or neoprene rubber. Read the assessment .

1,4 Dioxane

View the studies used in the 2010 IRIS Toxicological Review of 1,4 Dioxane

8/11/2010: 1,4-Dioxane is commonly used as a solvent, cleaning agent, chemical stabilizer, surface coatings, adhesive agent, and an ingredient in chemical manufacture.

Read the assessment

Ethylene Glycol Monobutyl Ether (EGBE)

View the studies used in the 2010 IRIS Toxicological Review of Ethylene Glycol Monobutyl Ether (EGBE)

3/31/2010: EPA announces the release of the final IRIS Toxicological Review of EGBE.

Ethylene Glycol Monobutyl Ether (EGBE) is used extensively as an industrial solvent. This assessment addresses both non-cancer and cancer human health effects that may result from chronic exposure to this chemical. Read the assessment

Acrylamide

View the studies used in the 2010 IRIS Toxicological Review of Acrylamide

3/22/2010: EPA announces the release of the final IRIS Toxicological Review of Acrylamide.

Acrylamide is a chemical used in the production of polyacrylamide polymers. This assessment addresses both non-cancer and cancer human health effects that may result from chronic exposure to this chemical. Read the assessment

Methanol

View the studies used in the Toxicological Review of Methanol (External Review Draft)

1/12/2010: EPA announces the release of the draft IRIS Toxicological Review of Methanol. It addresses both non-cancer and cancer human health effects that may result from chronic exposure to this chemical. Read the assessment .


Other Assessments

Nanoscale Silver Case Study

View the studies used in the Nanomaterial Case Study: Nanoscale Silver in Disinfectant Spray (External Review Draft)

8/13/2010: This draft document presents a case study of engineered nanoscale silver (nano-Ag), focusing on the specific example of nano-Ag as possibly used in disinfectant sprays. Read the assessment

Graphical Arrays of Reference Values for Inhalation Exposures

View the studies used in the Graphical Arrays

9/24/2009: Graphical Arrays of Chemical-Specific Health Effect Reference Values for Inhalation Exposures provides graphical arrays and tables of key information on the derivation of human inhalation health effect reference values for specific chemicals, allowing comparisons across durations, populations, and intended use.

Nanoscale Titanium Dioxide Case Studies

View the studies used in the Nanoscale Titanium Dioxide (External Review Draft)

7/31/2009: This draft document presents two case studies of nanoscale titanium dioxide (nano-TiO2) used (1) to remove arsenic from drinking water and (2) as an active ingredient in topical sunscreen. Read the assessment .

Basic Information Frequent Questions How to Use HERO Risk Assessment Process Transparency & Integrity Glossary Related Links
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Search

We've come a long way from the card catalogue! HERO's search engine makes it easy to search through the hundreds of thousands of studies used in risk assessment.

Evaluating Scientific Literature

Read about how EPA scientists use HERO to find and evaluate key studies.

  • Literature Search: Comprehensively and efficiently searching the world's literature.

  • Screening and Sorting : Innovative and cutting-edge tools used to sort and classify studies.

  • Identifying Key Studies : A systematic, transparent and collaborative process involving peer review and public participation.

More about the assessment development process. >>

Transparency - Participation - Collaboration

Public participation, transparency and collaboration are key elements to the success of HERO. The Open Government Directive is to break down long-standing barriers between the federal government and you. HERO helps accomplish this by sharing the scientific literature used in risk assessment development.

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