The Government of Southern Sudan is comprised of the following ministries:
 

1. Office of the President
    
2. Cabinet Affairs
    
3. SPLA and Veteran Affairs
    
4. Legal Affairs and Constitutional Development
    
5. Regional Cooperation 
    
6. Internal Affairs
    
7. Labour and Public Service
    
8. Parliamentary Affairs
    
9. Finance and Economic Planning
    
10. Roads and Transport 
     
11. Agriculture and Forestry 
     
12. Animal Resource and Fisheries 
     
13. Cooperatives and Rural Development
     
14. Energy and Mining
     
15. Commerce and Industry 
     
16. Wildlife Conservation and Tourism 
     
17. Water Resources and Irrigation 
     
18. Housing and Physical Planning
     
19. Education
     
20. Health 
     
21. Information
     
22. Communications and Postal Services 
     
23. Gender, Social Welfare and Religious Affairs 
     
24. Culture and Heritage
     
25. Investment
     
26. Human Resource Development
     
27. Environment
     
28. Higher Education, Science and Technology
     
29. Youth, Sports and Recreation
     
30. Humanitarian Affairs and Disaster Management
     
31. Peace and CPA Implementation Affairs