Stanford University Library homepage Stanford Web Archive Portal Home | Help
Showing http://web.stanford.edu/group/pawender/total-synthesis.html captured on Sep 20, 2015
Previous capture | Hide overlay | Next capture

Captured 36 times between June 21, 2015 and January 29, 2022

Year
1991 1995 2000 2005 2010 2014
Month
Jan Apr Aug Dec
Day
1st 5th 10th 15th 20th 25th 30th
  • Home
  • About Professor Wender
  • Group Members
  • Publications
    • New Reaction Development
    • Total Synthesis
    • Drug Design and Evaluation
    • Drug Delivery Systems
    • PKC and Receptors
    • Other Items
  • Research
    • Function Oriented Synthesis
    • New Therapies and Drugs
    • Drug Delivery
    • New Reaction Development
  • Media
  • Contact Us

Total Synthesis of Complex Molecules
Previous   Next

  • Wender, P.A.; "Toward the Ideal Synthesis and and Transformative Therapies: The Roles of Step Economy and Function Oriented Synthesis"; Tetrahedron, 2013, 69(36), pp. 7529-7550. Article.
  • Yasuyuki Ogawa, Phillip P. Painter, Dean J. Tantillo, and Paul A. Wender; "Mechanistic and Computational Studies of Exocyclic Stereocontrol in the Synthesis of Bryostatin-like Cis-2, 6-Disubstituted 4-Alkylidenetetrahydropyrans by Prins Cyclization"; J. Org. Chem., 2013, 78(1), pp. 104-115.Abstract, PDF, Supporting Information
  • Wender, Paul A. & Reuber, Jenny; "Function Oriented Synthesis: Preparation and Initial Biological Evaluation of New A-Ring-Modified Bryologs",Tetrahedron, 2011, 67, 9998-10005. Abstract, PDF.
  • Paul Wender & Adam Schrier; "Total Synthesis of Bryostatin 9", Journal of the American Chemical Society, 2011, 133(24), 9228-9231. Abstract,PDF.
  • Wender, Paul A.; Buschmann, Nicole; Cardin, Nathan B.; Jones, Lisa R.; Kan, Cindy; Kee, Jung-Min; Kowalski, John A.; Longcore, Kate E., “Gateway Synthesis of Daphnane Congeners and Their PKC Affinities and Cell-Growth Activities”, Nature Chemistry, 2011, 3, 615-619. Abstract
  • Adam Schrier, Brian Loy, and Paul A. Wender, “Translating Nature’s Library: the Bryostatins and Function-Oriented Synthesis” Israel J. Chem.,2011, 51, 453-472.
  • Wender, P. A.; D'Angelo, N.; Elitzin, V. I.; Ernst, M.; Jackson-Ugueto, E. E.; Kowalski, J. A.; McKendry, S.; Rehfeuter, M.; Sun, R.; Voigtlaender, D. "Function-Oriented Synthesis: Studies Aimed at the Synthesis and Mode of Action of 1a-Alkyldaphnane Analogues" Org. Lett., 2007, 9, 1829-1832. Abstract, PDF, Supporting Information
  • Wender, P. A.; Bi, F. C.; Buschmann, N.; Gosselin, F.; Kan, C.; Kee, J.-M.; Ohmura, H. "Studies on Oxidopyrylium [5 + 2] Cycloadditions: Toward a General Synthetic Route to the C12-Hydroxy Daphnetoxins" Org. Lett., 2006, 8, 5373-5376. Abstract, PDF, Supporting Information
  • Wender, P. A.; Koehler, M. F. T.; Sendzik, M. "A New Synthetic Approach to the C Ring of Known as Well as Novel Bryostatin Analogues" Org. Lett., 2003, 5, 4549-4552. Abstract, PDF, Supporting Information
  • Wender, P. A.; Hegde, S. G.; Hubbard, R. D.; Zhang, L.; Mooberry, S. L. "Synthesis and Biological Evaluation of (-)-Laulimalide Analogues" Org. Lett., 2003, 5, 3507-3509. Abstract, PDF, Supporting Information
  • Wender, P. A.; Baryza, J. L.; Brenner, S. E.; Clarke, M. O.; Gamber, G. G.; Horan, J. C.; Jessop, T. C.; Kan, C.; Pattabiraman, K.; Williams, T. J. "Inspirations from Nature. New Reactions, New Therapeutic Leads, and New Drug Delivery Systems" Pure Appl. Chem., 2003, 75, 143-156.Abstract, PDF
  • Wender, P. A.; Hegde, S. G.; Hubbard, R. D.; Zhang, L. "Total Synthesis of (-)-Laulimilide" J. Am. Chem. Soc., 2002, 124, 4956-4967. Abstract,PDF, Supporting Information
  • Wender, P. A.; Bi, F. C.; Brodney, M. A.; Gosselin, F. "Asymmetric Synthesis of the Tricyclic Core of NGF-inducing Cyathane Diterpenes via a Transition-Metal-Catalyzed [5+2] Cycloaddition" Org. Lett. 2001, 3, 2105-2108. Abstract, PDF, Supporting Information
  • Wender, P. A.; Zhang L. "Asymmetric Total Synthesis of (+)-Aphanamol I Based on the Transition Metal Catalyzed [5+2] Cycloaddition of Allenes and Vinylcyclopropanes Org. Lett. 2000, 2, 2323-2326. Abstract, PDF, Supporting Information
  • Wender, P. A.; Hinkle K. W. "Synthesis and Biological Evaluation of A New Class of Bryostatin Analogues: the Role of the C20 Substituent in Protein Kinase C Binding" Tetrahedon Lett. 2000, 41, 6725-6729. PDF
  • Wender, P. A.; Lippa B. "Synthesis and Biological Evaluation of Bryostatin Analogues: the Role of the A-Ring" Tetrahedon Lett. 2000, 41, 1007-1011. PDF
  • Wender, P. A.; Fuji, M; Husfeld, C. O.; Love, J. A. "Rhodium-Catalyzed [5+2] Cycloadditions of Allenes and Vinylcyclopropanes: Asymmetric Total Synthesis of (+)-Dictamnol" Org. Lett. 1999, 1, 137-139. Abstract, PDF, Supporting Information
  • Wender, P. A.; Hinkle, K. W.; Koehler, M. F. T.; Lippa, B. "The Rational Design of Potential Chemotherapeutic Agents: Synthesis of Bryostatin Analogues" Med. Res. Rev. 1999, 19, 388-407. Abstract, PDF
  • Wender, P. A.; Debrabander, J.; Harran, P. G.; Jimenez, J. M.; Koehler, M. F. T.; Lippa, B.; Park, C. M.; Shiozaki, M."Synthesis of the First Members of A New Class of Biologically Active Bryostatin Analogues" J. Am. Chem. Soc. 1998, 120, 4534-4535. PDF, Supporting Information
  • Wender, P. A.; Dore T. M. "A Formal Synthesis of Crinipellin B Based on the Arene-Alkene Meta-Photocycloaddition Reaction" Tetrahedon Lett.1998, 39, 8589-8592. Abstract, PDF
  • Wender, P. A.; Handy S. T., Wright D. L. "Towards the Ideal Synthesis" Chemistry & Industry 1997, 765.
  • Wender, P. A.; Badham, N. F.; Conway, S. P.; Floreancig, P. E.; Glass, T. E.; Houze, J. B.; Krauss, N. .E; Lee, D. S.; Marquess, D. G.; Mcgrane, P. L.; Meng, W. "The Pinene Path To Taxanes. 6. A Concise Stereocontrolled Synthesis of Taxol" J. Am. Chem. Soc. 1997, 119, 2757-2758. PDF,Supporting Information
  • Wender, P. A.; Rice K. D., Schnute M. E. "The First Formal Asymmetric Synthesis of Phorbol" J. Am. Chem. Soc. 1997, 119, 7897-7898. PDF,Supporting Information
  • Wender, P. A.; Jesudason, C. D.; Nakahira, H.; Tamura, N.; Tebbe, A. L., Ueno, Y. "The First Synthesis of a Daphnane Diterpene: the Enantiocontrolled Total Synthesis of (+)-Resiniferatoxin" J. Am. Chem. Soc. 1997, 119, 12976-12977. PDF, Supporting Information
  • Wender, P. A.; Nuss, J. M.; Smith, D. B.; Suarezsobrino, A.; Vagberg, J.; Decosta, D.; Bordner, J. "Transition Metal Catalyzed Cycloadditions: An Intramolecular [4+4] Cycloaddition Strategy for the Efficient Synthesis of Dicyclopenta[A,D]Cyclooctene 5-8-5 Ring Systems" J. Org. Chem. 1997,62, 4908-4909. PDF, Supporting Information
  • Wender, P. A.; Badham, N. F.; Conway, S. P.; Floreancig, P. E.; Glass T. E.; Granicher, C.; Houze, J. B.; Janichen, J.; Lee, D. S.; Marquess, D. G. "The Pinene Path to Taxanes. 5. Stereocontrolled Synthesis of a Versatile Taxane Precursor" J. Am. Chem. Soc. 1997, 119, 2755-2756. PDF,Supporting Information
  • Wender, P. A.; Dore, T. M.; deLong, M. A. "An Arene-Alkene Photocycloaddition-Radical Cyclization Cascade: the First Syntheses of Cis,Cis,Cis,Trans-[5.5.5.5]-Fenestranes" Tetrahedon Lett. 1996, 37, 7687-7690. Abstract, PDF
  • Wender, P. A.; Smith, T. E. "Transition Metal-Catalyzed Intramolecular [4+2] Cycloadditions: A Novel Method for the Assembly of Nitrogen Heterocycles and its Application to Yohimban Alkaloid Synthesis"J. Org. Chem. 1996, 61, 824-825. PDF, Supporting Information
  • Wender, P. A.; Smith T. E."Transition Metal-Catalyzed Intramolecular [4+2] Cycloadditions: Initial Studies on Stereochemistry and on Steroid and Vitamin-D Analog Syntheses" J. Org. Chem. 1995, 60, 2962-2963. PDF
  • Wender, P. A.; Beckham, S.; Oleary, J. G. "A 2nd-Generation Photochemically Activatable Dynemicin Analog: A Concise Synthesis and DNA Cleavage Studies" Synthesis-Stuttgart 1994, 1278-1282.
  • Wender, P. A.; Natchus, M. G.; Shuker, A. J. "Towards the Total Synthesis of Taxol and its Analogs," in Taxol, Science and Applications; Matthew Suffness, Ed.; CRC Press, Inc, London; Pp. 123-187, 1995.
  • Wender, P. A.; Mucciaro, T. P. "A New and Practical Approach to the Synthesis of Taxol and Taxol Analogs: The Pinene Path" J. Am. Chem. Soc.1992, 114, 5878-5879. PDF
  • Wender, P. A.; deLong, M. A. "Synthetic Studies on Arene-Olefin Cycloadditions. XII. Total Synthesis of (+/-)-Subergorgic Acid" Tetrahedon Lett.1990, 31, 5429-5432. Abstract, PDF
  • Wender, P. A.; Singh, S. K. "Synthetic Studies on Arene-Olefin Cycloadditions. 11. Total Synthesis of (-)-Retigeranic Acid" Tetrahedon Lett. 1990,31, 2517-2520. Abstract, PDF
  • Wender, P. A.; Ternansky, R; deLong, M; Singh, S; Olivero, A; Rice, K. "Arene Alkene Cycloadditions and Organic-Synthesis" Pure Appl. Chem.1990, 62, 1597-1602.
  • Wender, P. A.; McDonald, F. E. "Studies on Tumor Promoters. 9. A 2nd-Generation Synthesis of Phorbol" J. Am. Chem. Soc. 1990, 112, 4956-4958.PDF
  • Wender, P. A.; Siggel, L.; Nuss, J. M. "Arene-Alkene Photocycloaddition Reaction," Org. Photochem. 10, 357, 1989.
  • Wender, P. A.; Kogen, H.; Lee, H. Y.; Munger, J. D.; Wilhelm, R. S.; Williams, P. D. "Studies on Tumor Promoters. 8. the Synthesis of Phorbol" J. Am. Chem. Soc. 1989, 111, 8957-8958. PDF
  • Wender, P. A.; Ihle, N. C.; Correia C. R. D. "Nickel-Catalyzed Intramolecular [4+4] Cyclo-Additions. 4. Enantioselective Total Synthesis of (+)-Asteriscanolide" J. Am. Chem. Soc. 1988, 110, 5904-5906. PDF
  • Wender, P. A.; Vongeldern, T. W.; Levine, B. H. "Synthetic Studies on Arene Olefin Cyclo-Additions. 10. A Concise, Stereocontrolled Total Synthesis of (+/-)-Laurenene" J. Am. Chem. Soc. 1988, 110, 4858-4860. PDF
  • Wender, P. A.; Harmata, M.; Jeffrey, D.; Mukai, C.; Suffert, J. "Studies on DNA-Active Agents: the Synthesis of the Parent Carbocyclic Subunit of Neocarzinostatin Chromophore-A" Tetrahedon Lett. 1988, 29, 909-912.
  • Wender, P. A.; Schaus, J. M., White, A. W."General Methodology for cis-Hydroisoquinoline Synthesis .3. A Sixteen Step Synthesis of Reserpine"Heterocycles 1987, 25, 263-270.
  • Wender, P. A.; Fisher, K. "The Total Synthesis of (+/-)-Rudmollin .9. 7-Membered Ring Synthesis Based on Arene Olefin Cycloadditions"Tetrahedon Lett. 1986, 27, 1857-1860.
  • Wender, P. A.; Singh, S. K. "Synthetic Studies on Arene-Olefin Cyclo-Additions .8. Total Syntheses of (+/-)-Silphiperfol-6-Ene, (+/-)-7-Alpha-H-Silphiperfol-5-Ene and (+/-)-7-Beta-H-Silphiperfol-5-Ene" Tetrahedon Lett. 1985, 26, 5987-5990.
  • Wender, P. A.; Holt, D. A. "Macroexpansion Methodology .3. 8-Step Synthesis of (-)-(3Z)-Cembrene-A" J. Am. Chem. Soc. 1985, 107, 7771-7772.PDF
  • Wender, P. A.; Wolanin, D. J. "Total Synthesis of Quadrone and Terrecyclic Acid-A" J. Org. Chem. 1985, 50, 4418-4420. PDF
  • Wender, P. A.; Ternansky R. J. "Synthetic Studies on Arene-Olefin Cyclo-Additions .7. A 3-Step Total Synthesis of (+/-)-Silphinene" Tetrahedon Lett. 1985, 26, 2625-2628.
  • Wender, P. A.; Howbert, J. J. "Synthetic Studies on Areneolefin Cyclo-Additions .6. 2 Syntheses of (+/-)-Coriolin" Tetrahedon Lett. 1983, 24, 5325-5328.
  • Wender, P. A.; Dreyer, G. B. "Synthetic Studies on Arene-Olefin Cyclo-Additions .5. Total Synthesis of (+/-)-Isoiridomyrmecin" Tetrahedon Lett.1983, 24, 4543-4546.
  • Wender, P. A.; Dreyer, G. B."Synthetic Studies on Arene-Olefin Cyclo-Additions .4. Total Synthesis of (+/-)-Modhephene" J. Am. Chem. Soc. 1982,104, 5805-5807. PDF
  • Wender, P. A.; Howbert, J. J. "Synthetic Studies on Arene-Olefin Cyclo-Additions .3. Total Synthesis of +/-Hirsutene" Tetrahedon Lett. 1982, 23, 3983-3986.
  • Wender, P. A.; Eck, S. L."The Olefin Metathesis Trans-Annular Ene Sequence: A Method for the Stereocontrolled Synthesis of Trans-Decalin Derivatives .3. Total Synthesis of (+/-)-Warburganal" Tetrahedon Lett. 1982, 23, 1871-1874.
  • Wender, P. A.; Dreyer, G. B. "Synthetic Studies on Arene-Olefin Cyclo-Additions .2. Total Synthesis of (+/-)-Isocomene" Tetrahedron 1981, 37, 4445-4450.
  • Wender, P. A.; Howbert, J. J. "Synthetic Studies on Arene-Olefin Cyclo-Additions: Total Synthesis of (-/+)-Alpha-Cedrene" J. Am. Chem. Soc. 1981,103, 688-690. PDF
  • Wender, P. A.; Lechleiter, J. C. "Total Synthesis of (+/-) Isabelin" J. Am. Chem. Soc. 1980, 102, 6340-6341. PDF
  • Wender, P. A.; Schaus, J. M.; White, A. W. "General Methodology for cis-Hydroisoquinoline Synthesis: Synthesis of Reserpine" J. Am. Chem. Soc.1980, 102, 6157-6159. PDF
  • Wender, P. A.; Letendre, L. J. "Olefin Metathesis Trans-Annular Ene Sequence: Method for the Stereocontrolled Synthesis of Trans-Decalin Derivatives .2. Formal Eudesmane Syntheses" J. Org. Chem. 1980, 45, 367-368. PDF
  • Wender, P. A.; Hubbs, J. C. "Olefin Metathesis Trans-Annular Ene Sequence: Method for the Stereocontrolled Synthesis of Trans-Decalin Derivatives .1. Total Synthesis of (+/-)-Calameon" J. Org. Chem. 1980, 45, 365-367. PDF
  • Wender, P. A.; Eissenstat, M. A.; Filosa, M. P. "General Methodology for Pseudoguaiane Synthesis: Total Synthesis of (+/-)-Damsinic Acid and (+/-)-Confertin" J. Am. Chem. Soc. 1979, 101, 2196-2198. PDF
  • Wender, P. A.; Lechleiter, J. C. "Photochemically Mediated [4c+2c] Annelation: Synthesis of (+/-)-10-Epijunenol" J. Am. Chem. Soc. 1978, 100, 4321-4322. PDF