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  • Exon junction complex

    The exon junction complex is shown to have a role in regulating alternative splicing and this is linked to Pol II

    Genome Biology 2014, 15:551
  • Discovering the piRNA pathway

    Transposable elements are repressed by a subclass of small interfering RNAs called piRNAs. Chantal Vaury and colleagues provide an update on the distinct features of the piRNA pathway, suggesting it is far different than previously though.

    Mobile DNA 2014, 5:28
  • Image attributed to: Lasseigne et al., BMC Medicine

    DNA methylation altered in kidney cancer

    A panel of DNA methylation markers distinguishes kidney tumors from noncancerous tissue in patients with renal cell carcinoma, suggesting that epigenetic biomarkers could be used to detect kidney cancer early and monitor therapy response.

    BMC Medicine 2014, 12:235
  • Image attributed to: wikimedia commons-Jucember

    Plant-based vaccines against viruses

    Dr Rybicki summarizes recent advances of plant-made or “biofarmed” vaccines, including the recent ZMapp for Ebola infection, and explores future applications of the technology.

    Virology Journal 2014, 11:205
  • Image attributed to: Crowd scene by Amy Mingo from Wikipedia commons

    The impact of personal genomics

    A description of the design and methods used in a collaboration between academia, 23andme and Pathway genomics to explore the effect of direct to consumer testing on participants.

    Genome Medicine 2014, 6:96
  • Image attributed to: Detail of Figure 4_from Malhotra et al.

    Mining biomarkers for Alzheimer's disease

    A gray zone approach combining text mining and context-specific modeling of molecular interactions underlying stages of Alzheimer's disease identifies potential biomarkers.

    Genome Medicine 2014, 6:97
  • Image attributed to: istock photo

    Circulating miRNAs linked to disease

    In a genome-wide profiling analysis across patients with 19 different diseases, a number of miRNAs found in blood have strong association with disease, emphasizing the potential of circulating miRNAs as minimally invasive diagnostic biomarkers.

    BMC Medicine 2014, 12:224
  • TET1 as co-activator

    In addition to its role in DNA demethylation, TET1 is shown to act as a co-activator in hypoxic conditions

    Genome Biology 2014, 15:513
  • HCC tumor suppressors

    Integrative analysis of 5mC and 5hmC in human hepatocellular carcinoma reveals several tumor suppressor candidate genes

    Genome Biology 2014, 15:533
  • Image attributed to: with wind, CC, Flickr

    Lifestyle factors to fight depression in MS

    Multiple sclerosis patients who regularly supplemented their diet with flaxseed oil and vitamin D, had frequent fish consumption, meditated, and had moderate alcohol consumption have significantly reduced risk of depression.

    BMC Psychiatry 2014, 14:327
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    Research Involvement and Engagement has now opened for submissions

    An innovative, health and social care journal that focuses on the patient.

    Led by two Editors-in-Chief: Sophie Staniszewska, PPI lead at RCN Research Institute, University of Warwick, UK, and Richard Stephens, a patient advocate in research, who has overcome a number of health challenges. This collaboration between a patient and an academic signals "our intention to work towards the co-production of knowledge that informs health care practice."

    The journal will have a novel structure, co-produced by all key stakeholders, including patients, academics, policy makers and service users. All articles within the journal will be reviewed by both academics and patients, with both reports carrying equal weight in the editorial decision.

    "We want to walk the walk as well as talk the talk, and we look forward to you joining us as fellow travellers on our journey, and as fellow contributors in this new journal.”

  • Thumbnail

    Climate Change Responses has now fully launched and has published its first articles

    An interdisciplinary journal dedicated to publishing exceptional research on ecological and evolutionary responses to climate change. The journal is especially interested in publishing ground-breaking work linking responses to environmental change across levels of biological organization, from individuals to ecosystems, and with an emphasis on species interactions.

    Read the interview with co-Editor-in-Chief, Frank Seebacher, to discover the aims and scope of Climate Change Responses and about Frank's own background as a research scientist. Find out more about the importance of studying the ecological impacts of climate change with co-Editor-in-Chief Eric Post interview with Biome

     

  • Thumbnail

    Journal of Compassionate Health Care (JCHC) has now fully launched

    This is the first open access journal that publishes leading research and perspectives in the growing field of compassionate health care. Read the Q+A with the Editors-in-Chief, Sue Shea and Christos Lionis, to find out more about the field and what they hope to achieve with the journal. 
    Click on the following links to dip into the first two research articles published and a case study by Robin Youngson, an international leader in compassionate healthcare.

     

  • Thumbnail

    Journal of Clinical Movement Disorders (JCMD) has now launched and published its first articles

    Edited by Dr Steven Frucht, JCMD focuses on scientific investigations into the diagnosis, evaluation and management of patients with involuntary movement disorders. The journal reviews, illustrates and emphasizes clinical phenomenology as an indispensable tool for the diagnosis and application of translational medicine to movement disorders. It also covers topics including Parkinson's disease, tremor, dystonia, myoclonus, Huntington's disease, tics, and pediatric movement disorders.

    For more information, please read the launch Editorial and an Editor Q&A with Dr Frucht published today in Biome.

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