The Protein and Nucleic Acid (PAN) Facility is a multifaceted biotechnology fee-for-service laboratory. The PAN Biotechnology Facility offers a diverse array of instrumentation and technical capabilities and plays a significant consultative role in the application of these technologies to basic science projects.
Description of Services
The PAN Biotechnology Facility offers a diverse array of instrumentation and technical capabilities and plays a significant consultative role in the application of these technologies to basic science projects. Such services include:
- Gene Expression
- Oligo Synthesis
- DNA Sequencing
- Real-Time PCR
- Pyrosequencing
- Surface Plasmon Resonance (Biacore)
- Peptide Synthesis
- Protein Analytics (Protein Sequencing/Mass Mapping)
- Mass Spectrometry
- Antibodies
Selected References
Transgenerational epigenetic inheritance of longevity in Caenorhabditis elegans. Greer EL, Maures TJ, Ucar D, Hauswirth AG, Mancini E, Lim JP, Benayoun BA, Shi Y and Brunet A. Nature 2011; 479: 365–371. PubMedID: 22012258
Antagonistic VEGF variants engineered to simultaneously bind to and inhibit VEGFR2 and αvβ3 integrin. Papo N, Silverman AP, Lahti JL, and Cochran JR. Proc Natl Acad Sci U S A. 2011 Aug 23; 108 (34): 14067-14072. PubMedID: 21825147; PMCID: PMC3161552
Masking the 5′ terminal nucleotides of the hepatitis C virus genome by an unconventional microRNA-target RNA complex. Machlin ES, Sarnow P and Sagan SM. Proc Natl Acad Sci U S A. 2011 Feb 22; 108(8): 3193–3198. PubMedID: 21220300; PMCID: PMC3044371
