Plasmacytoma

Clinical

About 5% of plasma cell neoplasms each are osseous and extraosseous plasmacytomas
Younger age at onset than overt myeloma
Lack anemia, hypercalcemia, and renal impairment
Osseous sites variable
- 50% involve spine as a single lesion
Extraosseous sites variable
- Most in oropharynx / nasoopharynx
- Minority may involve draining nodes
Myeloma develops in 2/3 of osseous plasmacytoma patients
Myeloma develops in 15% of extraosseous plasmacytoma patients