Home | Genetics

Current Issue

Volume 202 Issue 3, March 2016

Collective Fluctuations in the Dynamics of Adaptation and Other Traveling Waves
March 2016 | Oskar Hallatschek, Lukas Geyrhofer
The dynamics of adaptation are difficult to predict because it is highly stochastic even in large populations. The uncertainty emerges from random genetic drift arising...
Small Heat Shock Proteins Are Novel Common Determinants of Alcohol and Nicotine Sensitivity in Caenorhabditis elegans

March 2016 | James R. Johnson, Dayani Rajamanoharan, Hannah V. McCue, Kim Rankin, Jeff W. Barclay
Addiction to drugs is strongly determined by multiple genetic factors. Alcohol and nicotine produce distinct pharmacological effects within the nervous system through...
Static and Dynamic Factors Limit Chromosomal Replication Complexity in Escherichia coli, Avoiding Dangers of Runaway Overreplication

March 2016 | Sharik R. Khan, Tulip Mahaseth, Elena A. Kouzminova, Glen E. Cronan, Andrei Kuzminov
We define chromosomal replication complexity (CRC) as the ratio of the copy number of the most replicated regions to that of unreplicated regions on the same chromosome....
Genomic Patterns of Geographic Differentiation in Drosophila simulans

March 2016 | Alisa Sedghifar, Perot Saelao, David J. Begun
Geographic patterns of genetic differentiation have long been used to understand population history and to learn about the biological mechanisms of adaptation. Here we...
MicroRNA Biogenesis and Hedgehog-Patched Signaling Cooperate to Regulate an Important Developmental Transition in Granule Cell Development
March 2016 | Lena Constantin, Myrna Constantin, Brandon J. Wainwright
The Dicer1, Dcr-1 homolog (Drosophila) gene encodes a type III ribonuclease required for the canonical maturation and functioning of microRNAs...
A Conserved GEF for Rho-Family GTPases Acts in an EGF Signaling Pathway to Promote Sleep-like Quiescence in Caenorhabditis elegans

March 2016 | Amanda L. Fry, Jocelyn T. Laboy, Huiyan Huang, Anne C. Hart, Kenneth R. Norman
Sleep is evolutionarily conserved and required for organism homeostasis and survival. Despite this importance, the molecular and cellular mechanisms underlying sleep are...
Local Anesthetics and Antipsychotic Phenothiazines Interact Nonspecifically with Membranes and Inhibit Hexose Transporters in Yeast
March 2016 | Yukifumi Uesono, Akio Toh-e, Yoshiko Kikuchi, Tomoyuki Araki, Takushi Hachiya, Chihiro K. Watanabe, Ko Noguchi, Ichiro Terashima
Action mechanisms of anesthetics remain unclear because of difficulty in explaining how structurally different anesthetics cause similar effects. In Saccharomyces...
Hedgehog Signaling Strength Is Orchestrated by the mir-310 Cluster of MicroRNAs in Response to Diet

March 2016 | Ibrahim Ömer Çiçek, Samir Karaca, Marko Brankatschk, Suzanne Eaton, Henning Urlaub, Halyna R. Shcherbata
Since the discovery of microRNAs (miRNAs) only two decades ago, they have emerged as an essential component of the gene regulatory machinery. miRNAs have seemingly...

Current Highlights

Previous Highlights

Current Issue

Volume 202 Issue 3, March 2016

ABOUT GSA

The Genetics Society of America (GSA), founded in 1931, is the professional membership organization for scientific researchers and educators in the field of genetics.

Learn more

Submit an Article to GENETICS

GENETICS publishes high-quality scientific research that presents important findings in genetics and genomics across a full range of biological science applications. Learn more about the journal and the types of articles we publish, or get started with your submission.

Prepare materials

Genetics

Current Issue

RECENT ARTICLES ON THE GENES TO GENOMES BLOG

Current Issue

ABOUT GSA

Submit an Article to GENETICS

RECENT ARTICLES ON THE GENES TO GENOMES BLOG

RECENT ARTICLES ON THE GENES TO GENOMES BLOG