What we're talking about Bidding Antibiotics Adieu Friday, December 11, 2015

Bidding Antibiotics Adieu

Researchers in China identified a gene that confers resistance to a last-resort antibiotic, and then found that gene in E. coli isolates from raw meat samples, pigs, and 16% of hospital patients with infections.

I’ve been involved in a few discussions of late on science-based sites around yon web on antibiotic resistance and agriculture–specifically, the campaign to get fast food giant Subway to stop using meat raised on antibiotics, and a graphic by CommonGround using Animal Health Institute data, suggesting that agricultural animals aren’t an important source of resistant bacteria.…

I’m not going to say that Ron Howard is old or anything, but he isn’t Opie any more. (And, in fact, it has been fascinating and inspiring to watch his career, by the way.) Anyway, Howard produced a new documentary with National Geographic called “Breakthrough: The Age of Aging, which premieres Sunday, November 29 at…

On The Pump Handle, Liz Borkowski reports another crack in one of the pillars of modern life—antibiotics. New research in China shows that a family of bacteria called Enterobacteriaceae (which includes E. coli and Salmonella) have acquired a gene that provides resistance to a last-resort antibiotic known as Colistin. These species of bacteria do not have to evolve resistance individually—in fact, they can trade antibiotic-resistant genes with one another using "transmissible pieces of DNA–plasmids, transposons, phage." As Tara Smith writes, "Since the development of penicillin, we have been in an ongoing 'war' with the bacteria that make us ill." And thanks to the overuse of antibiotics in medicine and animal husbandry, we are losing out quickly. Like 20th century climate, 20th century medicine is something we have learned to take for granted and can't really imagine living without. One thing Greg Laden notes in his post about aging (and Ron Howard): "antibiotics alone probably allow a much larger proportion of the human population to survive long enough to experience age-related disease."

Channel Surfing

Life Science

We’ll have to advance the invasion plan. A scout squad of paper nautiluses have been exposed off the coast of California. Several of the scouts bravely tried to wrest the camera from the spy, but failed. We’re going to have to send some muscle to accompany the reconnaissance patrols from now on — all we…

Zinc deficiency is sometimes diagnosed in infants who are exclusively breast-fed. It can occur because of a dysfunctional zinc transporter in the mother, which prevents zinc from being secreted into the breast milk through a special zinc transporter in the epithelial cells of the mammary gland (Chowanadisai et al., 2006). It could also be inherited.…

The Discovery Institute thinks axon guidance mechanisms are evidence for intelligent design. I think they just trawl the scientific literature for the words “complex” and “purpose” and get really excited about the imaginary interpretations in their head of papers they don’t really understand. There’s no mention of evolution here, nor in the full paper in…

Physical Science

“I just think too many nice things have happened in string theory for it to be all wrong. Humans do not understand it very well, but I just don’t believe there is a big cosmic conspiracy that created this incredible thing that has nothing to do with the real world.” –Ed Witten If you calculate…

“Did you ever read my words, or did you merely finger through them for quotations which you thought might valuably support an already conceived idea concerning some old and distorted connection between us?” -Audre Lorde One of the most damning, albeit accurate, condemnations of String Theory that has been leveled at it is that it’s…

“You are the salt of the earth. But remember that salt is useful when in association, but useless in isolation.” -Israelmore Ayivor When NASA’s Dawn spacecraft began photographing Ceres, one big surprise emerged: the presence of a spectacularly and unusually bright spot at the bottom of Occator crater. As we got closer, we discovered it…

Environment

This week’s snapshot of just one work-related fatality in the US. This one occurred on Wednesday, November 25 in Chesterfield County, VA.

You are a scientists and you are doing two things. First, you have finished a preliminary study and submitted a grant proposal based on your evolving idea about something, and you have just submitted a related paper to a peer reviewed journal. Well, OK, that’s a bunch of things, but they are all related to…

I watched most of yesterday’s Senate hearings live (ironically titled Data or Dogma? Promoting Open Inquiry in the Debate over the Magnitude of Human Impact on Earth’s Climate), and what I missed, I sampled via the magic of recorded video. I considered fisking the hearings, in particular, the closing statement by Senator Ted Cruz (and…

Humanities

As noted a couple of days ago, this was a big martial arts week at Chateau Steelypips, with The Pip’s first-ever belt test on Monday, and SteelyKid testing for her brown belt tonight. Unfortunately, tonight was also a first, namely the first belt test she’s failed. This was, sadly, entirely predictable, as her teacher has…

The importance of protecting vulnerable workers in efforts to combat climate change; Dallas officials vote for mandatory rest breaks; University of Chicago’s nontenured instructors vote to form a union; and Cal/OSHA launches investigation into porn production company.

When we had our vetinary adventure back on Saturday, they drew blood for some tests. These showed that Emmy’s kidney function is somewhat impaired, leading to yet more tests, and as of last night an extensive regimen of new stuff: That’s some new kidney-friendly food (in both dry and canned varieties), a drug for her…

Education

Zinc deficiency is sometimes diagnosed in infants who are exclusively breast-fed. It can occur because of a dysfunctional zinc transporter in the mother, which prevents zinc from being secreted into the breast milk through a special zinc transporter in the epithelial cells of the mammary gland (Chowanadisai et al., 2006). It could also be inherited.…

You are probably thinking, whose bird-brained idea was that? Well, as it turns out, a new study published in PLOS ONE shows that pigeons can be trained to accurately differentiate cancerous versus healthy tissue biopsies. This is because the process of diagnosing cancer involves visual screening of MRIs an biopsies and pigeons use similar visual processing…

A new study published in PLOS ONE that examined bitter taste receptors in cats may provide evidence as to why felines are such finicky eaters. Unlike my cat that seems to take after Garfield in his dietary choices, most cats are purely carnivorous. Cats are reportedly unable to taste sweets thus plant-based starches are not…

Politics

You can accuse Sam Harris of a lot of things, but being a bad writer is not one of them. Sometimes I agree with him, sometimes I basically agree but think his manner of expression makes life too easy for his critics, and sometimes I disagree. But I always feel like I understand perfectly what…

You are a scientists and you are doing two things. First, you have finished a preliminary study and submitted a grant proposal based on your evolving idea about something, and you have just submitted a related paper to a peer reviewed journal. Well, OK, that’s a bunch of things, but they are all related to…

I watched most of yesterday’s Senate hearings live (ironically titled Data or Dogma? Promoting Open Inquiry in the Debate over the Magnitude of Human Impact on Earth’s Climate), and what I missed, I sampled via the magic of recorded video. I considered fisking the hearings, in particular, the closing statement by Senator Ted Cruz (and…

Medicine

Although I don’t write about him as much as I used to, there was a time a couple of years ago when Houston cancer quack Stanislaw Burzynski was a frequent topic of this blog. His story, detailed in many posts on this blog and in an article I wrote for Skeptical Inquirer, is one that…

Zinc deficiency is sometimes diagnosed in infants who are exclusively breast-fed. It can occur because of a dysfunctional zinc transporter in the mother, which prevents zinc from being secreted into the breast milk through a special zinc transporter in the epithelial cells of the mammary gland (Chowanadisai et al., 2006). It could also be inherited.…

Many are the “alternative” medicine therapies that I’ve examined with a skeptical eye over the years. The vast majority of them rest on concepts that range from pre-scientific to religious to outright pseudoscientific to—let’s face it—the utterly ridiculous. Examples abound: Reflexology, reiki, tongue diagnosis, homeopathy, ear candling, cupping, crystal healing, urine drinking, detoxifying foot pads,…

Brain & Behavior

Zinc deficiency is sometimes diagnosed in infants who are exclusively breast-fed. It can occur because of a dysfunctional zinc transporter in the mother, which prevents zinc from being secreted into the breast milk through a special zinc transporter in the epithelial cells of the mammary gland (Chowanadisai et al., 2006). It could also be inherited.…

You are probably thinking, whose bird-brained idea was that? Well, as it turns out, a new study published in PLOS ONE shows that pigeons can be trained to accurately differentiate cancerous versus healthy tissue biopsies. This is because the process of diagnosing cancer involves visual screening of MRIs an biopsies and pigeons use similar visual processing…

Of all the slick woo peddlers out there, one of the most famous (and most annoying) is Deepak Chopra. Indeed, he first attracted a bit of not-so-Respectful Insolence a mere 10 months after this blog started, when Chopra produced the first of many rants against nasty “skeptics” like me that I’ve deconstructed over the years.…

Technology

No. Lights of the christmas tree interfering with The Force, not likely. Well, OK, if all the people in the united states gathered into one state, the gravitational effects of all those bodies in one place would be detectable by the ultra sensitive GRACE satellite system. And, any electronic device that is running, including light…

Researchers in China are exploring the use of gene-editing technologies to create customized animals. Take for example research at the Shaanxi Provincial Engineering and Technology Research Center for Shaanbei Cashmere Goats where animals have been genetically-modified to have longer hair (i.e. more wool) and more muscles (i.e. meat). This was accomplished using the relatively new technology CRISPR-Cas9 developed in…

Mike Haubrich and I are planning a science oriented podcasting effort. It will be called “Ikonokast” (all the good names, like “The New York Times” and “Apple” were taken). We decided to enhance the podcast with a WordPress based blog site, perhaps with each page representing one podcast, and containing backup and supplementary information. After…

Information Science

This latest book in my reviewing adventures continues the recentish trend of books concerned with science during World War II. Michael Hiltzik’s Big Science: Ernest Lawrence and the Invention that Launched the Military-Industrial Complex follows books such as Serving the Reich: The Struggle for the Soul of Physics under Hitler, Planck: Driven by Vision, Broken…

As you all have no doubt noticed over the years, I love highlighting the best science books every year via the various end of year lists that newspapers, web sites, etc. publish. I’ve done it so far in 2008, 2009, 2010, 2011, 2012, 2013 and 2014. And here we are in 2015! As in previous…

As you all have no doubt noticed over the years, I love highlighting the best science books every year via the various end of year lists that newspapers, web sites, etc. publish. I’ve done it so far in 2008, 2009, 2010, 2011, 2012, 2013 and 2014. And here we are in 2015! As in previous…

Jobs

This week’s snapshot of just one work-related fatality in the US. This one occurred on Wednesday, November 25 in Chesterfield County, VA.

The importance of protecting vulnerable workers in efforts to combat climate change; Dallas officials vote for mandatory rest breaks; University of Chicago’s nontenured instructors vote to form a union; and Cal/OSHA launches investigation into porn production company.

My neighborhood’s mail carrier is now responsible for delivering packages from Amazon. Did the USPS deal-makers consider how these new demands on postal workers increase their risk of suffering an injury or other adverse health consequences?