NK and Target Cell Interaction
Elucidating the mechanisms by which NK cells interact with and regulate target cells.
Research Interests
Epstein-Barr Virus
Determining the factors involved in growth and survival of EBV+ B cell lymphomas.
microRNA Immune Regulators
Investigating the role of microRNAs as master regulators in immune responses in transplantation and viral infections (especially EBV).
Plasmacytoid Dendritic Cells
Investigating the role of plasmacytoid dendritic cells and microRNAs in tolerance.
NK Response to EBV
Understanding and phenotyping the natural killer (NK) cell response to EBV+ B cell lymphomas, and how we might exploit this knowledge to generate novel cellular immunotherapies for these diseases.
Mechanisms of Transplant Tolerance
Investigating the immunological and molecular mechanisms behind transplant tolerance.
Stem Cells as a Source of New Tissues and Organs
Organ shortage is a major problem in the field of transplantation. We are developing novel approaches to generate hepatocyte-like cells from stem cells for transplantation.
