STE6 / YKL209C

Sequence Help

Sequence Overview

Sequences and genome annotation information for Reference Strain S288C and a select set of Alternative References.


Protein Product
ATP-binding cassette alpha-factor transporter STE6
Feature Type
ORF , Verified
Description
Plasma membrane ATP-binding cassette (ABC) transporter; required for the export of a-factor, catalyzes ATP hydrolysis coupled to a-factor transport; contains 12 transmembrane domains and two ATP binding domains; expressed only in MATa cells; human homolog ABCB1 mediates multidrug resistance in many chemotherapy-resistant tumors by effluxing toxic compounds from the cell 2 3 4 5 6 7
EC Number
3.6.3.48

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