Lipid Rich Carcinoma of the Breast
Definition
- Breast carcinoma exhibiting clear cytoplasm due to lipid
Alternate / Historical Names
- Lipid secreting carcinoma
Diagnostic Criteria
- Clear, multivacuolated or foamy cytoplasm
- May have areas of oxyphilic cytoplasm
- Abundant intracytoplasmic lipid
- Oil red O or Sudan III stain positive
- Requires unprocessed tissue
- Oil red O or Sudan III stain positive
- May have any grade cytology
- Wide variety of patterns
- Nests, cords, sheets, alveoli
Richard L Kempson MD
Robert V Rouse MD
Department of Pathology
Stanford University School of Medicine
Stanford CA 94305-5342
Original posting:: May 1, 2006