Tubular Adenosis of the Breast
Definition
- Benign haphazard proliferation of elongated tubules
Diagnostic Criteria
- Elongated tubules
- Occasional branching
- May have thick basement membrane
- Lumens variable
- Collapsed to dilated
- No apical snouts
- Lumenal eosinophilic colloid-like or basophilic secretion
- Focal lumenal calcification
- Cytologically bland
- Small indististinct nucleoli
- MItotic figures uncommon
- Haphazard distribution
- Poorly circumscribed
- At most vague lobular grouping
- Not crowded
- May infiltrate fat
- Background of fibrous or fatty tissue
- Generally hypocellular, may be focally cellular
- Myoepithelial layer present
Richard L Kempson MD
Robert V Rouse MD
Department of Pathology
Stanford University School of Medicine
Stanford CA 94305-5342
Original posting: May 27, 2006