The Stanford Magnetic Resonance Laboratory is a research facility within the Stanford University School of Medicine. The goal of this facility is to provide research instrumentation and expertise in the area of solution-phase, high resolution Nuclear Magnetic Resonance (NMR) spectroscopy.
The research focus of the facility is primarily in the study of biological macromolecules. Collaborating researchers also use the facility to study properties of polymers, minerals, soils, and for NMR imaging experiments.
Available Equipment
Instrumentation include Varian Inova 800 and 600 MHz spectrometers, Bruker Avance 500 MHz spectrometer, and access to the Central California Bruker 900 MHz spectrometer at UC-Berkeley. Three of the spectrometers are equipped with cryogenic probes (800 Cold Probe, 500/900 CryoProbes)
Selected References
Ligand-specific regulation of the extracellular surface of a G-protein-coupled receptor. Bokoch MP, Zou Y, Rasmussen SG, Liu CW, Nygaard R, Rosenbaum DM, Fung JJ, Choi HJ, Thian FS, Kobilka TS, Puglisi JD, Weis WI, Pardo L, Prosser RS, Mueller L, Kobilka BK. Nature. 2010 Jan 7;463(7277):108-12. PubMedID: 20054398.
Phosphorus forms and chemistry in the soil profile under long-term conservation tillage: a phosphorus-31 nuclear magnetic resonance study. Cade-Menun BJ, Carter MR, James DC, Liu CW. J Environ Qual. 2010 Sep-Oct;39(5):1647-56. PubMedID: 21043270.
Small-molecule displacement of a cryptic degron causes conditional protein degradation. Bonger KM, Chen LC, Liu CW, Wandless TJ. Nat Chem Biol. 2011 Jul 3;7(8):531-7. PubMedID: 21725303.
