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Cancer

A piece of the p53 puzzle

Nature volume 520, pages 3738 (02 April 2015) | Download Citation

An iron-dependent form of cell death called ferroptosis has been implicated as a component of the tumour-suppressor activity of p53, providing fresh insight into how this protein prevents cancer development. See Article p.57

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References

  1. 1.

    & Genes Dev. 26, 1268–1286 (2012).

  2. 2.

    et al. Nature 520, 57–62 (2015).

  3. 3.

    Nature 358, 15–16 (1992).

  4. 4.

    & Cell 137, 413–431 (2009).

  5. 5.

    et al. Cell 145, 571–583 (2011).

  6. 6.

    et al. Cell 149, 1269–1283 (2012).

  7. 7.

    et al. Cell Rep. 3, 1339–1345 (2013).

  8. 8.

    & Amino Acids 42, 231–246 (2012).

  9. 9.

    et al. Cell 149, 1060–1072 (2012).

  10. 10.

    , & Nature Rev. Cancer 14, 359–370 (2014).

  11. 11.

    et al. Cell 156, 317–331 (2014).

Download references

Author information

Affiliations

  1. Kathryn T. Bieging and Laura D. Attardi are in the Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California 94305-5152, USA.

    • Kathryn T. Bieging
    •  & Laura D. Attardi
  2. L.D.A. is also in the Department of Genetics, Stanford University School of Medicine, Stanford, California 94305-5152, USA.

    • Laura D. Attardi

Authors

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Corresponding author

Correspondence to Laura D. Attardi.

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DOI

https://doi.org/10.1038/nature14374

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