ASSFN Proceedings 2004
A Preliminary Study of Transient Confusional States following Bilateral Subthalamic Stimulation for Parkinson’s DiseasePilitsis J.G.a · Rezai A.R.b · Boulis N.M.b · Henderson J.M.d · Busch R.M.c · Kubu C.S.caDepartment of Neurosurgery, Wayne State University, Detroit, Mich., bCenter for Neurological Restoration and cDepartment of Psychiatry and Psychology, Cleveland Clinic Foundation, Cleveland, Ohio, dDepartment of Neurosurgery, Stanford University, Stanford, Calif., USA
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Article / Publication Details
Published online: August 26, 2005
Issue release date: August 2005
Number of Print Pages: 4
Number of Figures: 2
Number of Tables: 1
ISSN: 1011-6125 (Print)
eISSN: 1423-0372 (Online)
For additional information: https://www.karger.com/SFN
Abstract
Transient postoperative confusion (POC) occurs in 5–25% of patients following bilateral subthalamic nucleus stimulation. We retrospectively reviewed data on 96 patients who underwent bilateral subthalamic nucleus deep brain stimulation for Parkinson’s disease. Nine percent of patients developed POC. There was no significant correlation between age/perioperative factors and POC. The POC group had a significantly higher incidence of depression and frontal-subcortical dysfunction on preoperative evaluation than patients without POC. Postoperative neuropsychological evaluations revealed declines on measures of general cognitive function and memory in the POC group. We provide preliminary evidence that patients with depression and frontal-subcortical dysfunction are more likely to develop POC, and that POC is more often associated with cognitive decline following surgery.
© 2005 S. Karger AG, Basel
References
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Article / Publication Details
Published online: August 26, 2005
Issue release date: August 2005
Number of Print Pages: 4
Number of Figures: 2
Number of Tables: 1
ISSN: 1011-6125 (Print)
eISSN: 1423-0372 (Online)
For additional information: https://www.karger.com/SFN
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Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
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