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1 - 10 of 33 results for: MI

MI 18SC: The Coming Influenza Pandemic

Examines the H1N1 influenza virus from molecular, clinical, societal, historical, demographic, economic, and political perspectives. Examines the unique genetic, epidemiological, virologic, and pathogenic features of the influenza virus that allow it to continue to reinvent itself and re-emerge on an annual basis. Discusses past successes and failures, the current status of influenza, and the critical factors to consider to avert the coming influenza pandemic. Explores whether or not the lessons learned from influenza can be applied to other diseases. Includes guest lectures, field trips, student presentations.
Terms: not given this year | Units: 2 | Grading: Satisfactory/No Credit

MI 19SC: Measles and Sneezles and Things That Go Mumps in the Night

A study of measles (until recently one of the leading causes of death in the world and the most contagious disease agent ever studied) and its relatives in the paramyxovirus family, including mumps, respiratory syncytial virus, hendra, and nipah, as well as a number of important animal pathogens. Investigates the nature of viruses using the paramyxoviruses as a paradigm. Topics include: the history of this devastating group of pathogens; basic aspects of paramyxovirus taxonomy and molecular virology; viral epidemiology, emergence, and eradication, including the pioneering studies of Peter Panum; the use, misuse, and abuse of science; the interactions between pathogen and host and how this interplay leads to disease, including the appearance of a bizarre brain complication with 100% mortality; the politics and economics of infection; how a putative link between the measles vaccine and autism entered the public eye, and how it refuses to disappear despite overwhelming evidence to the contrary. Field trips, guest speakers, student presentations. No science background necessary.
Terms: not given this year | Units: 2 | Grading: Satisfactory/No Credit

MI 27SC: Viruses in the News

Viruses are unique biological entities that resemble both living and inanimate objects. Despite their simple structure they include some of the most devastating and ubiquitous causes of human disease. The compelling nature of this topic is illustrated by the recent Ebola epidemic, which emerged coincident with the last time this class was offered. From smallpox to measles to HIV to the common cold, viruses have literally changed the course of human history and impacted evolution. They have also been important experimental tools for probing the molecular nature of key biological processes, and they have been utilized in many key discoveries and Nobel Prize-winning research programs. In books, movies, newspapers, and electronic feeds, viruses continue to make the news on a daily basis. Using contemporary media, content experts, model building, interactive sessions, and field trips, we will explore the essential nature of viruses, what makes them unique, how they are classified, how they cause disease, key molecular processes, breakthroughs in prevention and treatment, current efforts in trying to eradicate viruses, and cultural iconography pertaining to viruses. In short, this seminar is intended to go viral. Sophomore College course, applications required, due at noon on April 5, 2016. Apply at http://soco.stanford.edu .
Terms: Sum | Units: 2 | Grading: Letter or Credit/No Credit
Instructors: Siegel, R. (PI)

MI 70Q: Photographing Nature

Utilizes the idiom of photography to learn about nature, enhance observation, and explore scientific concepts. Builds upon the pioneering photographic work of Eadweard J. Muybridge on human and animal locomotion. A secondary goal is to learn the grammar, syntax, composition, and style of nature photography to enhance the use of this medium as a form of scientific communication and also to explore the themes of change across time and space. Scientific themes to be explored include: taxonomy, habitat preservation, climate change; species diversity; survival and reproductive strategies; ecological niches and coevolution, carrying capacity and sustainability, population densities, predation, and predator-prey relationships, open-space management, the physics of photography. Extensive use of field trips and class critque.
Terms: Spr | Units: 3 | Grading: Satisfactory/No Credit
Instructors: Siegel, R. (PI)

MI 104: Innate Immunology (IMMUNOL 204, MI 204)

Innate immune mechanisms as the only defenses used by the majority of multicellular organisms. Topics include Toll signaling, NK cells, complement, antimicrobial peptides, phagocytes, neuroimmunity, community responses to infection, and the role of native flora in immunity. How microbes induce and defeat innate immune reactions, including examples from vertebrates, invertebrates, and plants.
Terms: Spr | Units: 3 | Grading: Medical Option (Med-Ltr-CR/NC)

MI 115B: The Vaccine Revolution (HUMBIO 155B)

Advanced seminar. Human aspects of viral disease, focusing on recent discoveries in vaccine development and emerging infections. Journal club format: students choose articles from primary scientific literature, write formal summaries, and synthesize them into a literature review. Emphasis is on analysis, experimental design, and interpretation of data. Oral presentations. Enrollment limited to 8. Prerequisite: prior enrollment in HumBio 155H Humans and Viruses or MI 116, The Human Virosphere
Terms: Spr | Units: 6 | Grading: Letter (ABCD/NP)
Instructors: Siegel, R. (PI)

MI 115C: Human Virology Inquiry Project l

Advanced topics in human virology focuses on current issues in the field. Topics will include: clinical features of infection, epidemiology, molecular virology, drug development and policy, vaccinology, pathogenesis, host modulation, and media representations of viral infection. Student presentations and discussion in a small group setting.
Terms: not given this year | Units: 1-3 | Grading: Letter (ABCD/NP)

MI 116: The Human Virosphere (MI 216)

Focus on interaction of humans and viruses from a number of perspectives: historical, cultural, political, and demographic. Organismal, molecular biological, biochemical, human and viral interactions; clinical aspects of viral disease, epidemiology and risk factors, public and international health, aspects of virology including emerging viruses and biological weapons. Case studies involving particular viruses: human herpes viruses, retroviruses, oncogenic viruses; vaccination and disease eradication, evolution of viruses as tools for research and therapy. Emphasis on general principles of biology and matters of decision making policy. Prerequisite: Biology core, Human Biology core, or consent of instructor.
Terms: not given this year | Units: 5 | Grading: Medical Option (Med-Ltr-CR/NC)

MI 120: Bacteria in Health and Disease (BIO 120)

Enrollment limited to junior and senior undergraduates, graduate students and medical students. Introduces students to the bacteria that live in and on humans and, in some cases, can cause disease and sometimes death. Topics include the biology of the interaction of the simple microbe with complex human biology and the factors that determine whether or not we coexist relatively peacefully, suffer from overt disease, or succumb to the bacterial onslaught.
Terms: not given this year | Units: 3 | Grading: Letter or Credit/No Credit

MI 155H: Humans and Viruses I (HUMBIO 155H)

Introduction to human virology integrating epidemiology, molecular biology, clinical sciences, social sciences, history, and the arts. Emphasis is on host pathogen interactions and policy issues. Topics: polio and vaccination, smallpox and eradication, yellow fever and history, influenza and genomic diversity, rubella and childhood infections, adenovirus and viral morphology, ebola and emerging infection, lassa fever and immune response.
Terms: not given this year | Units: 6 | Grading: Letter (ABCD/NP)
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