School of Medicine
Showing 211-220 of 220 Results
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Kristen Marie Wortman
Postdoctoral Research Fellow, Neurosurgery
Current Research and Scholarly Interests My work seeks to explore how personality relates to other cognitive skills in those with a history of TBI. Work will also explore personality as biomarker, mediating or moderating treatment response in traumatic brain injury, other medical/psychological comorbidities, and quality of life. Under the mentorship of Maheen Adamson, Ph.D, I will also be involved with rTMS treatment and neuroimaging methods. I am also completing hours for licensure, performing neuropsychological assessments in our TBI clinic. Essentially the final goal is to learn about the relationship of personality and cognitive skills in order to develop treatment for those who are unresponsive to treatment likely due to personality factors.
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Heng Zhao
Associate Professor (Research) of Neurosurgery
Current Research and Scholarly Interests My lab is focused on developing novel therapeutic methods against stroke using rodent models. We study protective effect of postconditioning, preconditioning and mild hypothermia. The rationale for studying three means of neuroprotection is that we may discover mechanisms that these treatments have in common. Conversely, if they have differing mechanisms, we will be able to offer more than one treatment for stroke and increase a patients chance for recovery.
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Brad Zuchero, Ph.D.
Assistant Professor of Neurosurgery
Current Research and Scholarly Interests Glia are a frontier of neuroscience, and overwhelming evidence from the last decade shows that they are essential regulators of all aspects of the nervous system. The Zuchero Lab aims to uncover how glial cells regulate neural development and how their dysfunction contributes to diseases like multiple sclerosis (MS) and in injuries like stroke.
Although glia represent more than half of the cells in the human brain, fundamental questions remain to be answered. How do glia develop their highly specialized morphologies and interact with neurons to powerfully control form and function of the nervous system? How is this disrupted in neurodegenerative diseases and after injury? By bringing cutting-edge cell biology techniques to the study of glia, we aim to uncover how glia help sculpt and regulate the nervous system and test their potential as novel, untapped therapeutic targets for disease and injury.
We are particularly interested in myelin, the insulating sheath around neuronal axons that is lost in diseases like MS. How do oligodendrocytes- the glial cell that produces myelin in the central nervous system- form and remodel myelin, and why do they fail to regenerate myelin in disease? Our current projects aim to use cell biology and neuroscience approaches to answer these fundamental questions. Ultimately we hope our work will lead to much-needed therapies to promote remyelination in patients.
