Bio
Dr. Glenn's primary interest is in molecular virology, with a strong emphasis on translating this knowledge into novel antiviral therapies. Current projects aim to better understand the role of prenylation in the life cycles of hepatitis delta virus (HDV) and other viruses--both as a mechanism of intracellular trafficking and trigger of virus assembly, and as a target for a promising antiviral treatment. The function and cell biology of hepatitis and respiratory virus proteins are also being studied, with a focus on identifying key determinants of pathogenesis and designing novel antiviral strategies for hepatitis, influenza, and enteroviruses. Of particular interest are targets in host cells upon which viruses depend, and critical RNA secondary structures in viruses. Other interests include exploitation of hepatic stem cells, development of small animal models, NASH, liver cancer, and engineered human liver tissues.
Clinical Focus
- Gastroenterology
Academic Appointments
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Professor, Medicine - Gastroenterology & Hepatology
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Professor, Microbiology & Immunology
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Member, Bio-X
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Faculty Fellow, Stanford ChEM-H
Administrative Appointments
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Director, Center for Hepatitis and Liver Tissue Engineering (2006 - Present)
Honors & Awards
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Translational Research Award, American Liver Foundation/Amgen/AASLD (1998-2002)
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Regents Scholarship, U.C.S.F. (1984-1993)
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Elected member, American Society for Clinical Investigation (2008)
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Clinical Scientist Award in Translational Research, Burroughs Wellcome Fund (2005-2010)
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Career Award, Burroughs Wellcome Fund (1998-2005)
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Physician Postdoctoral Fellowship Award, Howard Hughes Medical Institute (1995-1998)
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Summa cum laude, U.C. Berkeley (1984)
Professional Education
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Residency: Stanford University Internal Medicine Residency (1995) CA
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Board Certification: Gastroenterology, American Board of Internal Medicine (1998)
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Fellowship: Stanford University Gastroenterology Fellowship (1998) CA
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Medical Education: University of California at San Francisco School of Medicine (1993) CA
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Ph.D., U.C.S.F., Biochemistry and Biophysics (1992)
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M.D., U.C.S.F., Medicine/MSTP (1993)