Maximilian Diehn, MD, PhD

Publications

• An ultrasensitive method for quantitating circulating tumor DNA with broad patient coverage
  Newman, A. M., Bratman, S. V., To, J., Wynne, J. F., Eclov, N. Cw., & Diehn, M. (2014). An ultrasensitive method for quantitating circulating tumor DNA with broad patient coverage. NATURE MEDICINE, 20(5), 552-558.
• Neuregulin Autocrine Signaling Promotes Self-Renewal of Breast Tumor-Initiating Cells by Triggering HER2/HER3 Activation
  Lee, C. Y.-F., Lin, Y., Bratman, S. V., Feng, W., Kuo, A. H., & Diehn, M. (2014). Neuregulin Autocrine Signaling Promotes Self-Renewal of Breast Tumor-Initiating Cells by Triggering HER2/HER3 Activation. CANCER RESEARCH, 74(1), 341-352.
• Association of reactive oxygen species levels and radioresistance in cancer stem cells
  Diehn, M., Cho, R. W., Lobo, N. A., Kalisky, T., Dorie, M. J., & Clarke, M. F. (2009). Association of reactive oxygen species levels and radioresistance in cancer stem cells. NATURE, 458(7239), 780-U123.
• Outcomes of Modestly Hypofractionated Radiation for Lung Tumors: Pre- and Mid-Treatment Positron Emission Tomography-Computed Tomography Metrics as Prognostic Factors. Harris, J. P., Chang-Halpenny, C. N., Maxim, P. G., Quon, A., Graves, E. E., & Loo, B. W. (2015). Outcomes of Modestly Hypofractionated Radiation for Lung Tumors: Pre- and Mid-Treatment Positron Emission Tomography-Computed Tomography Metrics as Prognostic Factors. Clinical lung cancer, 16(6), 475-485.
  
• Predicting Radiotherapy Responses and Treatment Outcomes Through Analysis of Circulating Tumor DNA. Chaudhuri, A. A., Binkley, M. S., Osmundson, E. C., Alizadeh, A. A., & Diehn, M. (2015). Predicting Radiotherapy Responses and Treatment Outcomes Through Analysis of Circulating Tumor DNA. Seminars in radiation oncology, 25(4), 305-312.
  
• Integrating Tumor and Stromal Gene Expression Signatures With Clinical Indices for Survival Stratification of Early-Stage Non-Small Cell Lung Cancer. Gentles, A. J., Bratman, S. V., Lee, L. J., Harris, J. P., Feng, W., & Diehn, M. (2015). Integrating Tumor and Stromal Gene Expression Signatures With Clinical Indices for Survival Stratification of Early-Stage Non-Small Cell Lung Cancer. Journal of the National Cancer Institute, 107(10).
  
• Precision Hypofractionated Radiation Therapy in Poor Performing Patients With Non-Small Cell Lung Cancer: Phase 1 Dose Escalation Trial Westover, K. D., Loo, B. W., Gerber, D. E., Iyengar, P., Choy, H., & Timmerman, R. (2015). Precision Hypofractionated Radiation Therapy in Poor Performing Patients With Non-Small Cell Lung Cancer: Phase 1 Dose Escalation Trial. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 93(1), 72-81.
  
• Inhibition of Mouse Breast Tumor-Initiating Cells by Calcitriol and Dietary Vitamin D Jeong, Y., Swami, S., Krishnan, A. V., Williams, J. D., Martin, S., & Diehn, M. (2015). Inhibition of Mouse Breast Tumor-Initiating Cells by Calcitriol and Dietary Vitamin D. MOLECULAR CANCER THERAPEUTICS, 14(8), 1951-1961.
  
• The prognostic landscape of genes and infiltrating immune cells across human cancers Gentles, A. J., Newman, A. M., Liu, C. L., Bratman, S. V., Feng, W., & Alizadeh, A. A. (2015). The prognostic landscape of genes and infiltrating immune cells across human cancers. NATURE MEDICINE, 21(8), 938-945.
  
• Colorectal Histology Is Associated With an Increased Risk of Local Failure in Lung Metastases Treated With Stereotactic Ablative Radiation Therapy Binkley, M. S., Trakul, N., Jacobs, L. R., von Eyben, R., Quynh-Thu Le, Q. T., & Diehn, M. (2015). Colorectal Histology Is Associated With an Increased Risk of Local Failure in Lung Metastases Treated With Stereotactic Ablative Radiation Therapy. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 92(5), 1044-1052.
  
• Stereotactic ablative radiotherapy (SABR) for treatment of central and ultra-central lung tumors Chaudhuri, A. A., Tang, C., Binkley, M. S., Jin, M., Wynne, J. F., & Diehn, M. (2015). Stereotactic ablative radiotherapy (SABR) for treatment of central and ultra-central lung tumors. LUNG CANCER, 89(1), 50-56.
  
• Analysis of Long-Term 4-Dimensional Computed Tomography Regional Ventilation After Radiation Therapy King, M. T., Maxim, P. G., Diehn, M., Loo, B. W., & Xing, L. (2015). Analysis of Long-Term 4-Dimensional Computed Tomography Regional Ventilation After Radiation Therapy. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 92(3), 683-690.
  
• Noninvasive monitoring of diffuse large B-cell lymphoma by immunoglobulin high-throughput sequencing Kurtz, D. M., Green, M. R., Bratman, S. V., Scherer, F., Liu, C. L., & Alizadeh, A. A. (2015). Noninvasive monitoring of diffuse large B-cell lymphoma by immunoglobulin high-throughput sequencing. BLOOD, 125(24), 3679-3687.
  
• TU-AB-201-06: Evaluation of Electromagnetically Guided High- Dose Rate Brachytherapy for Ablative Treatment of Lung Metastases. Pinkham, D. W., Shultz, D., Loo, B. W., Sung, A., Diehn, M., & Fahimian, B. P. (2015). TU-AB-201-06: Evaluation of Electromagnetically Guided High- Dose Rate Brachytherapy for Ablative Treatment of Lung Metastases. Medical physics, 42(6), 3595-?.
  
• Robust enumeration of cell subsets from tissue expression profiles. Newman, A. M., Liu, C. L., Green, M. R., Gentles, A. J., Feng, W., & Alizadeh, A. A. (2015). Robust enumeration of cell subsets from tissue expression profiles. Nature methods, 12(5), 453-457.
  
• Robust enumeration of cell subsets from tissue expression profiles Newman, A. M., Liu, C. L., Green, M. R., Gentles, A. J., Feng, W., & Alizadeh, A. A. (2015). Robust enumeration of cell subsets from tissue expression profiles. NATURE METHODS, 12(5), 453-?.
  
• Noninvasive pulmonary nodule elastometry by CT and deformable image registration Negandar, M., Fasola, C. E., Yu, A. S., von Eyben, R., Yamamoto, T., & Maxim, P. G. (2015). Noninvasive pulmonary nodule elastometry by CT and deformable image registration. RADIOTHERAPY AND ONCOLOGY, 115(1), 35-40.
  
• To SABR or Not to SABR? Indications and Contraindications for Stereotactic Ablative Radiotherapy in the Treatment of Early-Stage, Oligometastatic, or Oligoprogressive Non-Small Cell Lung Cancer Shultz, D. B., Diehn, M., & Loo, B. W. (2015). To SABR or Not to SABR? Indications and Contraindications for Stereotactic Ablative Radiotherapy in the Treatment of Early-Stage, Oligometastatic, or Oligoprogressive Non-Small Cell Lung Cancer. SEMINARS IN RADIATION ONCOLOGY, 25(2), 78-86.
  
• FACTERA: a practical method for the discovery of genomic rearrangements at breakpoint resolution Newman, A. M., Bratman, S. V., Stehr, H., Lee, L. J., Liu, C. L., & Alizadeh, A. A. (2014). FACTERA: a practical method for the discovery of genomic rearrangements at breakpoint resolution. BIOINFORMATICS, 30(23), 3390-3393.
  
• Galectin-1 Mediates Radiation-Related Lymphopenia and Attenuates NSCLC Radiation Response Kuo, P., Bratman, S. V., Shultz, D. B., von Eyben, R., Chan, C., & Quynh-Thu Le, Q. T. (2014). Galectin-1 Mediates Radiation-Related Lymphopenia and Attenuates NSCLC Radiation Response. CLINICAL CANCER RESEARCH, 20(21), 5558-5569.
  
• Pulmonary Ventilation Imaging Based on 4-Dimensional Computed Tomography: Comparison With Pulmonary Function Tests and SPECT Ventilation Images Yamamoto, T., Kabus, S., Lorenz, C., Mittra, E., Hong, J. C., & Keall, P. J. (2014). Pulmonary Ventilation Imaging Based on 4-Dimensional Computed Tomography: Comparison With Pulmonary Function Tests and SPECT Ventilation Images. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 90(2), 414-422.
  
• Lung Volume Reduction After Stereotactic Ablative Radiation Therapy of Lung Tumors: Potential Application to Emphysema Binkley, M. S., Shrager, J. B., Leung, A. N., Popat, R., Trakul, N., & Loo, B. W. (2014). Lung Volume Reduction After Stereotactic Ablative Radiation Therapy of Lung Tumors: Potential Application to Emphysema. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 90(1), 216-223.
  
• Neurotrophic factor GDNF promotes survival of salivary stem cells Xiao, N., Lin, Y., Cao, H., Sirjani, D., Giaccia, A. J., & Quynh-Thu Le, Q. T. (2014). Neurotrophic factor GDNF promotes survival of salivary stem cells. JOURNAL OF CLINICAL INVESTIGATION, 124(8), 3364-3377.
  
• Vagal and recurrent laryngeal neuropathy following stereotactic ablative radiation therapy in the chest. Shultz, D. B., Trakul, N., Maxim, P. G., Diehn, M., & Loo, B. W. (2014). Vagal and recurrent laryngeal neuropathy following stereotactic ablative radiation therapy in the chest. Practical radiation oncology, 4(4), 272-278.
  
• Targeting Unique Metabolic Properties of Breast Tumor Initiating Cells Feng, W., Gentles, A., Nair, R. V., Huang, M., Lin, Y., & Diehn, M. (2014). Targeting Unique Metabolic Properties of Breast Tumor Initiating Cells. STEM CELLS, 32(7), 1734-1745.
  
• Imaging features associated with disease progression after stereotactic ablative radiotherapy for stage I non-small-cell lung cancer. Shultz, D. B., Trakul, N., Abelson, J. A., Murphy, J. D., Maxim, P. G., & Diehn, M. (2014). Imaging features associated with disease progression after stereotactic ablative radiotherapy for stage I non-small-cell lung cancer. Clinical lung cancer, 15(4), 294-301 e3.
  
• Feasibility and Potential Utility of Multicomponent Exhaled Breath Analysis for Predicting Development of Radiation Pneumonitis After Stereotactic Ablative Radiotherapy More, J. M., Eclov, N. Cw., Chung, M. P., Wynne, J. F., Shorter, J. H., & Diehn, M. (2014). Feasibility and Potential Utility of Multicomponent Exhaled Breath Analysis for Predicting Development of Radiation Pneumonitis After Stereotactic Ablative Radiotherapy. JOURNAL OF THORACIC ONCOLOGY, 9(7), 957-964.
  
• The effect of arm position on the dosimetry of thoracic stereotactic ablative radiation therapy using volumetric modulated arc therapy. Shultz, D. B., Jang, S. S., Hanlon, A. L., Diehn, M., Loo, B. W., & Maxim, P. G. (2014). The effect of arm position on the dosimetry of thoracic stereotactic ablative radiation therapy using volumetric modulated arc therapy. Practical radiation oncology, 4(3), 192-197.
  
• A Population-Based Comparative Effectiveness Study of Radiation Therapy Techniques in Stage III Non-Small Cell Lung Cancer Harris, J. P., Murphy, J. D., Hanlon, A. L., Quynh-Thu Le, Q. T., Loo, B. W., & Diehn, M. (2014). A Population-Based Comparative Effectiveness Study of Radiation Therapy Techniques in Stage III Non-Small Cell Lung Cancer. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 88(4), 872-884.
  
• Erythropoietin promotes breast tumorigenesis through tumor-initiating cell self-renewal Zhou, B., Damrauer, J. S., Bailey, S. T., Hadzic, T., Jeong, Y., & Kim, W. Y. (2014). Erythropoietin promotes breast tumorigenesis through tumor-initiating cell self-renewal. JOURNAL OF CLINICAL INVESTIGATION, 124(2), 553-563.
  
• Illuminating radiogenomic characteristics of glioblastoma multiforme through integration of MR imaging, messenger RNA expression, and DNA copy number variation. Jamshidi, N., Diehn, M., Bredel, M., & Kuo, M. D. (2014). Illuminating radiogenomic characteristics of glioblastoma multiforme through integration of MR imaging, messenger RNA expression, and DNA copy number variation. Radiology, 270(1), 1-2.
  
• Clinical implementation of intrafraction cone beam computed tomography imaging during lung tumor stereotactic ablative radiation therapy. Li, R., Han, B., Meng, B., Maxim, P. G., Xing, L., & Loo, B. W. (2013). Clinical implementation of intrafraction cone beam computed tomography imaging during lung tumor stereotactic ablative radiation therapy. International journal of radiation oncology, biology, physics, 87(5), 917-923.
  
• 4D CT lung ventilation images are affected by the 4D CT sorting method. Yamamoto, T., Kabus, S., Lorenz, C., Johnston, E., Maxim, P. G., & Keall, P. J. (2013). 4D CT lung ventilation images are affected by the 4D CT sorting method. Medical physics, 40(10), 101907-?.
  
• Clinical impact of dose overestimation by effective path length calculation in stereotactic ablative radiation therapy of lung tumors. Liu, M. B., Eclov, N. Cw., Trakul, N., Murphy, J., Diehn, M., & Loo, B. W. (2013). Clinical impact of dose overestimation by effective path length calculation in stereotactic ablative radiation therapy of lung tumors. Practical radiation oncology, 3(4), 294-300.
  
• Migration of implanted markers for image-guided lung tumor stereotactic ablative radiotherapy. Hong, J. C., Eclov, N. Cw., Yu, Y., Rao, A. K., Dieterich, S., & Maxim, P. G. (2013). Migration of implanted markers for image-guided lung tumor stereotactic ablative radiotherapy. Journal of applied clinical medical physics , 14(2), 4046-?.
  
• The Optimal Use of Radiotherapy in Small Cell Lung Cancer Shultz, D. B., Grecula, J. C., Hayman, J., Diehn, M., & Loo, B. W. (2013). The Optimal Use of Radiotherapy in Small Cell Lung Cancer. JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK, 11(1), 107-114.
  
• Migration of implanted markers for image-guided lung tumor stereotactic ablative radiotherapy Hong, J. C., Eclov, N. Cw., Yu, Y., Rao, A. K., Dieterich, S., & Maxim, P. G. (2013). Migration of implanted markers for image-guided lung tumor stereotactic ablative radiotherapy. JOURNAL OF APPLIED CLINICAL MEDICAL PHYSICS, 14(2), 77-89.
  
• Metabolic imaging metrics correlate with survival in early stage lung cancer treated with stereotactic ablative radiotherapy Abelson, J. A., Murphy, J. D., Trakul, N., Bazan, J. G., Maxim, P. G., & Loo, B. W. (2012). Metabolic imaging metrics correlate with survival in early stage lung cancer treated with stereotactic ablative radiotherapy. LUNG CANCER, 78(3), 219-224.
  
• Stereotactic Ablative Radiotherapy for Reirradiation of Locally Recurrent Lung Tumors Trakul, N., Harris, J. P., Le, Q.-T., Hara, W. Y., Maxim, P. G., & Diehn, M. (2012). Stereotactic Ablative Radiotherapy for Reirradiation of Locally Recurrent Lung Tumors. JOURNAL OF THORACIC ONCOLOGY, 7(9), 1462-1465.
  
• Tumor Volume-Adapted Dosing in Stereotactic Ablative Radiotherapy of Lung Tumors Trakul, N., Chang, C. N., Harris, J., Chapman, C., Rao, A., & Diehn, M. (2012). Tumor Volume-Adapted Dosing in Stereotactic Ablative Radiotherapy of Lung Tumors. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 84(1), 231-237.
  
• Intrafraction Verification of Gated RapidArc by Using Beam-Level Kilovoltage X-Ray Images Li, R., Mok, E., Chang, D. T., Daly, M., Loo, B. W., & Xing, L. (2012). Intrafraction Verification of Gated RapidArc by Using Beam-Level Kilovoltage X-Ray Images. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 83(5), E709-E715.
  
• What the Diagnostic Radiologist Needs to Know about Radiation Oncology Terezakis, S. A., Heron, D. E., Lavigne, R. F., Diehn, M., & Loo, B. W. (2011). What the Diagnostic Radiologist Needs to Know about Radiation Oncology. RADIOLOGY, 261(1), 30-44.
  
• HIGH RETENTION AND SAFETY OF PERCUTANEOUSLY IMPLANTED ENDOVASCULAR EMBOLIZATION COILS AS FIDUCIAL MARKERS FOR IMAGE-GUIDED STEREOTACTIC ABLATIVE RADIOTHERAPY OF PULMONARY TUMORS Hong, J. C., Yu, Y., Rao, A. K., Ditererich, S., Maxim, P. G., & Loo, B. W. (2011). HIGH RETENTION AND SAFETY OF PERCUTANEOUSLY IMPLANTED ENDOVASCULAR EMBOLIZATION COILS AS FIDUCIAL MARKERS FOR IMAGE-GUIDED STEREOTACTIC ABLATIVE RADIOTHERAPY OF PULMONARY TUMORS. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 81(1), 85-90.
  
• Reducing 4D CT artifacts using optimized sorting based on anatomic similarity Johnston, E., Diehn, M., Murphy, J. D., Loo, B. W., & Maxim, P. G. (2011). Reducing 4D CT artifacts using optimized sorting based on anatomic similarity. MEDICAL PHYSICS, 38(5), 2424-2429.
  
• Tumor Volume as a Potential Imaging-Based Risk-Stratification Factor in Trimodality Therapy for Locally Advanced Non-small Cell Lung Cancer Kozak, M. M., Murphy, J. D., Schipper, M. L., Donington, J. S., Zhou, L., & Loo, B. W. (2011). Tumor Volume as a Potential Imaging-Based Risk-Stratification Factor in Trimodality Therapy for Locally Advanced Non-small Cell Lung Cancer. JOURNAL OF THORACIC ONCOLOGY, 6(5), 920-926.
  
• The Myc Connection: ES Cells and Cancer Rothenberg, M. E., Clarke, M. F., & Diehn, M. (2010). The Myc Connection: ES Cells and Cancer. CELL, 143(2), 184-186.
  
• STEREOTACTIC ABLATIVE RADIOTHERAPY SHOULD BE COMBINED WITH A HYPOXIC CELL RADIOSENSITIZER Brown, J. M., Diehn, M., & Loo, B. W. (2010). STEREOTACTIC ABLATIVE RADIOTHERAPY SHOULD BE COMBINED WITH A HYPOXIC CELL RADIOSENSITIZER. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 78(2), 323-327.
  
• Metastatic Cancer Stem Cells: An Opportunity for Improving Cancer Treatment? Diehn, M., & Majeti, R. (2010). Metastatic Cancer Stem Cells: An Opportunity for Improving Cancer Treatment?. CELL STEM CELL, 6(6), 502-503.
  
• Identification, molecular characterization, clinical prognosis, and therapeutic targeting of human bladder tumor-initiating cells Chan, K. S., Espinosa, I., Chao, M., Wong, D., Ailles, L., & Weissman, I. L. (2009). Identification, molecular characterization, clinical prognosis, and therapeutic targeting of human bladder tumor-initiating cells. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 106(33), 14016-14021.
  
• Downregulation of miRNA-200c Links Breast Cancer Stem Cells with Normal Stem Cells Shimono, Y., Zabala, M., Cho, R. W., Lobo, N., Dalerba, P., & Clarke, M. F. (2009). Downregulation of miRNA-200c Links Breast Cancer Stem Cells with Normal Stem Cells. CELL, 138(3), 592-603.
  
• Therapeutic Implications of the Cancer Stem Cell Hypothesis Diehn, M., Cho, R. W., & Clarke, M. F. (2009). Therapeutic Implications of the Cancer Stem Cell Hypothesis. SEMINARS IN RADIATION ONCOLOGY, 19(2), 78-86.
  
• Identification of noninvasive imaging surrogates for brain tumor gene-expression modules Diehn, M., Nardini, C., Wang, D. S., McGovern, S., Jayaraman, M., & Kuo, M. D. (2008). Identification of noninvasive imaging surrogates for brain tumor gene-expression modules. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 105(13), 5213-5218.
  
• Isolation and molecular characterization of cancer stem cells in MMTV-Wnt-1 murine breast tumors Cho, R. W., Wang, X., Diehn, M., Shedden, K., Chen, G. Y., & Clarke, M. F. (2008). Isolation and molecular characterization of cancer stem cells in MMTV-Wnt-1 murine breast tumors. STEM CELLS, 26(2), 364-371.
  
• Type I collagen is overexpressed in medulloblastoma as a component of tumor microenvironment Liang, Y., Diehn, M., Bollen, A. W., Israel, M. A., & Gupta, N. (2008). Type I collagen is overexpressed in medulloblastoma as a component of tumor microenvironment. JOURNAL OF NEURO-ONCOLOGY, 86(2), 133-141.
  
• Cancer stem cells and radiotherapy: New insights into tumor radioresistance Diehn, M., & Clarke, M. F. (2006). Cancer stem cells and radiotherapy: New insights into tumor radioresistance. JOURNAL OF THE NATIONAL CANCER INSTITUTE, 98(24), 1755-1757.
  
• Cell-type specific gene expression profiles of leukocytes in human peripheral blood Palmer, C., Diehn, M., Alizadeh, A. A., & Brown, P. O. (2006). Cell-type specific gene expression profiles of leukocytes in human peripheral blood. BMC GENOMICS, 7.
  
• Genome-scale identification of membrane-associated human mRNAs Diehn, M., Bhattacharya, R., Botstein, D., & Brown, P. O. (2006). Genome-scale identification of membrane-associated human mRNAs. PLOS GENETICS, 2(1), 39-50.
  
• Gene expression profiling reveals molecularly and clinically distinct subtypes of glioblastoma multiforme Liang, Y., Diehn, M., Watson, N., Bollen, A. W., Aldape, K. D., & Israel, M. A. (2005). Gene expression profiling reveals molecularly and clinically distinct subtypes of glioblastoma multiforme. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 102(16), 5814-5819.
  
• Differential gene expression in anatomical compartments of the human eye Diehn, J. J., Diehn, M., Marmor, M. F., & Brown, P. O. (2005). Differential gene expression in anatomical compartments of the human eye. GENOME BIOLOGY, 6(9).
  
• A method for detecting and correcting feature misidentification on expression microarrays Tu, I. P., Schaner, M., Diehn, M., Sikic, B. I., Brown, P. O., & Fero, M. J. (2004). A method for detecting and correcting feature misidentification on expression microarrays. BMC GENOMICS, 5.
  
• Presynaptic homeostasis at CNS nerve terminals compensates for lack of a key Ca2+ entry pathway Piedras-Renteria, E. S., Pyle, J. L., Diehn, M., Glickfeld, L. L., Harata, N. C., & Tsien, R. W. (2004). Presynaptic homeostasis at CNS nerve terminals compensates for lack of a key Ca2+ entry pathway. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 101(10), 3609-3614.
  
• Gene expression patterns in ovarian carcinomas Schaner, M. E., Ross, D. T., Ciaravino, G., Sorlie, T., Troyanskaya, O., & Sikic, B. I. (2003). Gene expression patterns in ovarian carcinomas. MOLECULAR BIOLOGY OF THE CELL, 14(11), 4376-4386.
  
• T cell receptor-independent basal signaling via Erk and Abl kinases suppresses RAG gene expression Roose, J. P., Diehn, M., Tomlinson, M. G., Lin, J., Alizadeh, A. A., & Weiss, A. (2003). T cell receptor-independent basal signaling via Erk and Abl kinases suppresses RAG gene expression. PLOS BIOLOGY, 1(2), 271-287.
  
• T cell receptor-independent basal signaling via Erk and Abl kinases suppresses RAG gene expression. Roose, J. P., Diehn, M., Tomlinson, M. G., Lin, J., Alizadeh, A. A., & Weiss, A. (2003). T cell receptor-independent basal signaling via Erk and Abl kinases suppresses RAG gene expression. PLoS biology, 1(2), E53-?.
  
• Individuality and variation in gene expression patterns in human blood Whitney, A. R., Diehn, M., Popper, S. J., Alizadeh, A. A., Boldrick, J. C., & Brown, P. O. (2003). Individuality and variation in gene expression patterns in human blood. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 100(4), 1896-1901.
  
• SOURCE: a unified genomic resource of functional annotations, ontologies, and gene expression data Diehn, M., Sherlock, G., Binkley, G., Jin, H., Matese, J. C., & Alizadeh, A. A. (2003). SOURCE: a unified genomic resource of functional annotations, ontologies, and gene expression data. NUCLEIC ACIDS RESEARCH, 31(1), 219-223.
  
• Genomic expression programs and the integration of the CD28 costimulatory signal in T cell activation Diehn, M., Alizadeh, A. A., Rando, O. J., Liu, C. L., Stankunas, K., & Brown, P. O. (2002). Genomic expression programs and the integration of the CD28 costimulatory signal in T cell activation. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 99(18), 11796-11801.
  
• Transformation of follicular lymphoma to diffuse large-cell lymphoma: Alternative patterns with increased or decreased expression of c-myc and its regulated genes Lossos, I. S., Alizadeh, A. A., Diehn, M., Warnke, R., Thorstenson, Y., & Levy, R. (2002). Transformation of follicular lymphoma to diffuse large-cell lymphoma: Alternative patterns with increased or decreased expression of c-myc and its regulated genes. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 99(13), 8886-8891.
  
• Transcriptional response of human mast cells stimulated via the Fc(epsilon)RI and identification of mast cells as a source of IL-11. Sayama, K., Diehn, M., Matsuda, K., Lunderius, C., Tsai, M., & Galli, S. J. (2002). Transcriptional response of human mast cells stimulated via the Fc(epsilon)RI and identification of mast cells as a source of IL-11. BMC immunology, 3, 5-?.
  
• In vivo regulation of human skeletal muscle gene expression by thyroid hormone Clement, K., Viguerie, N., Diehn, M., Alizadeh, A., Barbe, P., & Langin, D. (2002). In vivo regulation of human skeletal muscle gene expression by thyroid hormone. GENOME RESEARCH, 12(2), 281-291.
  
• Stereotyped and specific gene expression programs in human innate immune responses to bacteria Boldrick, J. C., Alizadeh, A. A., Diehn, M., Dudoit, S., Liu, C. L., & Relman, D. A. (2002). Stereotyped and specific gene expression programs in human innate immune responses to bacteria. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 99(2), 972-977.
  
• Transcriptional programs activated by exposure of human prostate cancer cells to androgen DePrimo, S. E., Diehn, M., Nelson, J. B., Reiter, R. E., Matese, J., & Brooks, J. D. (2002). Transcriptional programs activated by exposure of human prostate cancer cells to androgen. GENOME BIOLOGY, 3(7).
  
• Comparing functional genomic datasets: lessons from DNA. microarray analyses of host-pathogen interactions Diehn, M., & Relman, D. A. (2001). Comparing functional genomic datasets: lessons from DNA. microarray analyses of host-pathogen interactions. CURRENT OPINION IN MICROBIOLOGY, 4(1), 95-101.
  
• Examining the living genome in health and disease with DNA microarrays Diehn, M., Alizadeh, A. A., & Brown, P. O. (2000). Examining the living genome in health and disease with DNA microarrays. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 283(17), 2298-2299.
  
• Large-scale identification of secreted and membrane-associated gene products using DNA microarrays Diehn, M., Eisen, M. B., Botstein, D., & Brown, P. O. (2000). Large-scale identification of secreted and membrane-associated gene products using DNA microarrays. NATURE GENETICS, 25(1), 58-62.
  
• Degradation of proteins from the ER of S-cerevisiae requires an intact unfolded protein response pathway Casagrande, R., Stern, P., Diehn, M., Shamu, C., Osario, M., & Ploegh, H. (2000). Degradation of proteins from the ER of S-cerevisiae requires an intact unfolded protein response pathway. MOLECULAR CELL, 5(4), 729-735.
  
• Biochemical interactions integrating Itk with the T cell receptor-initiated signaling cascade Bunnell, S. C., Diehn, M., Yaffe, M. B., Findell, P. R., Cantley, L. C., & Berg, L. J. (2000). Biochemical interactions integrating Itk with the T cell receptor-initiated signaling cascade. JOURNAL OF BIOLOGICAL CHEMISTRY, 275(3), 2219-2230.