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Microarray Analysis of Gene Expression and Identification of Progenitor Cells in Lung Carcinoma
This study will investigate gene expression profiles in normal human lung tissue, lung carcinoma and metastatic tumor to the lung. The expression of up to 20,000 genes in a given lung tissue sample will be examined by cDNA microarray analysis and compared to normal lung tissue. In addition, we hope to identify a particular subset of lung cancer cells with an enhanced capacity for proliferation and self-renewal , analogous to the stem cells recently identified for certain types of leukemia, breast cancer and brain tumors.
Stanford Investigator(s)
- Irving Weissman
- Heather Wakelee
- Joseph Shrager
- Chuong D. Hoang