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Radiosurgical Neuromodulation for Refractory Depression
This study is designed to evaluate the safety and effectiveness of an investigational
procedure for treating people with treatment resistant bipolar depression. Precise dose
delivery of radiation to the predetermined targets in the brain will be accomplished with
known Cyberknife stereotactive radiosurgery methods.. This technology is considered to be
noninvasive (does not physically invade your body). We will be studying if the Cyberknife
influences the sensitivity of certain nerves of your brain. Although many clinical
treatments for psychiatric conditions have been done using stereotactive radiosurgery, the
present study is experimental, because we are seeking to use more moderate doses of
radiation that are intended not to destroy any brain cells, but to normalize or modulate
their function.
Principal Investigator
- John R. Adler, MD
Stanford Investigator(s)
- Hugh Brent Solvason PhD MD
- Charles DeBattista