Pseudomonas aeruginosa is a major human pathogen and an important cause of morbidity and mortality in wound infections. With the increasing prevalence of antibiotic-resistant bacterial strains, new treatment strategies are required. P. aeruginosa’s survival is predicated on its ability to form biofilms, slimy layers of sugars and lipids that encase the microbial community and protect it from immune clearance. I use models of human wound healing and biochemical tools to study how the biofilm composition mediates immune suppression. Ultimately, my research will improve the understanding behind the regulation of inflammatory immune responses during biofilm infections and yield novel therapeutic targets.