E. Han Dao

I am a research assistant in the NPI group at PULSE. I work primarily under the supervision and mentorship of Dr. Hasan Demirci, focusing primarily on X-ray crystallography of mutant prokaryotic ribosomes. My work generally involves the typical sample preparation workflows for crystallography as well as methods development/refinement for crystallography done at LCLS.

At PULSE, I have taken part in both synchrotron cryocrystallography (SSRL) and in ambient-temperature serial femtosecond crystallography at the LCLS. The developments in imaging technologies is without a doubt very exciting with the emergence of such breakthroughs as high-resolution cryo-EM and now also with LCLS. I am interested not only in the structural biology of ribosomes but also in making methods for SFX more accessible to the wider scientific community as has been done for synchrotron based crystallography.