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Joseph Shrager
Thoracic surgeon, Surgical oncologist
Dr. Shrager has been identified as one of “America’s Top Doctors” and one of “America’s Top Doctors for Cancer” in Castle Connolly’s prestigious listings for multiple years running. Dr. Shrager has been awarded US News and World Report “Top Doctor” recognition in every year since that rating system was inaugurated in 2012 ; this award places him among the top 1% of thoracic surgeons nationwide based upon reviews by physician-peers. Evidence of his expert status among his peers also includes membership on the editorial board of the Annals of Thoracic Surgery.
Dr. Shrager practices all aspects of thoracic surgery but has specials interest and experience in lung cancer, surgery for emphysema, and mediastinal diseases. His clinical publications reflect these interests. In all cases, he looks towards minimally invasive approaches where appropriate, including VATS (thoracoscopic) lobectomy for early stage lung cancer and transcervical thymectomy.
In the basic research realm, Dr. Shrager has focused upon the responses of the respiratory muscles to various disease states and interventions. His lab’s work has been published in important journals such as The New England Journal of Medicine, The Journal of Thoracic and Cardiovascular Surgery, and The American Journal of Respiratory and Critical Care Medicine.
Practice Areas
Professional Education
- Board Certification: General Surgery, American Board of Surgery (1996)
- Medical Education: Harvard Medical School (1988) MA
- Residency: Massachusetts General Hospital (1997) MA
- Board Certification: Thoracic Surgery, American Board of Thoracic Surgery (1999)
- Residency: Hospital of the University of Pennsylvania (1995) PA
- Thoracic Surgery, Massachusetts General Hospital, Thoracic Surgery (1997)
- Surgery Training, Hospital of the Univ of Penn, Surgery (1995)
- MD, Harvard University, Medicine (1988)
Honors & Awards
- Phi Beta Kappa, Junior year induction, Amherst College (1983)
- Summa Cum Lauda, Amherst College (1984)
- Manstein Graduation Prize, Amherst College (Top Premed Athlete) (1984)
- Havighurst Graduation Prize, Amherst College (Top History Thesis) (1984)
- Simpson Fellowship, (For study at Harvard Medical School) (1984-1988)
- Cabot Graduation Prize, Harvard Medical School (1988)
- William I Inouye Award for Excellence in Teaching, Department of Surgery, University of Pennsylvania Sch. of Med. (1991)
- National Research Service Award, National Institutes of Health (1990-1992)
- 2nd Edward D. Churchill Research Scholarship, American Association for Thoracic Surgery (1999-2001)
- Fellow, American College of Chest Physicians (2000)
- Fellow, American College of Surgeons (2001)
- Listed in Consumers Guide to Top Doctors, Center for the Study of Services (2001-2003)
- Top Docs Listing, Philadelphia Magazine (2002, 2005, 2006, 2007)
- Elected Member, American Association for Thoracic Surgery (2002)
- "Top Doctors" Listing, Americas Top Doctors for Cancer -- peer-elected (2006,07,08 09 10 11 12)
- "Top Doctors" Listing, Americas Top Doctors - peer elected (2007,08,09,10,11,12)
- Elected Member, Society of Clinical Surgery (2008)
- Elected Member, American Surgical Association (2010)
Administrative Appointments
- Director, Stanford Respiratory Muscle Research Laboratory (2008 - Present)
- Member, STS Workforce on Evidence-based Surgery (2006 - Present)
- Member, AATS Workforce on Education (2008 - Present)
- Editorial Board Member, Annals of Thoracic Surgery (2001 - Present)
- Chief, Section of General Thoracic Surgery, UPenn (2003 - 2007)
- Chief, Stanford Division of Thoracic Surgery (2008 - Present)
- Physician Leader Thoracic Oncology DMG, Stanford Cancer Center (2010 - Present)
Publications
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Lung Volume Reduction After Stereotactic Ablative Radiation Therapy of Lung Tumors: Potential Application to Emphysema
Binkley, M. S., Shrager, J. B., Leung, A. N., Popat, R., Trakul, N., & Loo, B. W. (2014). Lung Volume Reduction After Stereotactic Ablative Radiation Therapy of Lung Tumors: Potential Application to Emphysema. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 90(1), 216-223. -
Circulating Tumor Microemboli Diagnostics for Patients with Non-Small-Cell Lung Cancer
Carlsson, A., Nair, V. S., Luttgen, M. S., Keu, K. V., Horng, G., & Gambhir, S. S. (2014). Circulating Tumor Microemboli Diagnostics for Patients with Non-Small-Cell Lung Cancer. JOURNAL OF THORACIC ONCOLOGY, 9(8), 1111-1119. -
Thoracoscopic lobectomy is associated with acceptable morbidity and mortality in patients with predicted postoperative forced expiratory volume in 1 second or diffusing capacity for carbon monoxide less than 40% of normal.
Burt, B. M., Kosinski, A. S., Shrager, J. B., Onaitis, M. W., & Weigel, T. (2014). Thoracoscopic lobectomy is associated with acceptable morbidity and mortality in patients with predicted postoperative forced expiratory volume in 1 second or diffusing capacity for carbon monoxide less than 40% of normal. journal of thoracic and cardiovascular surgery, 148(1), 19-?. -
Malignant pleural mesothelioma and the Society of Thoracic Surgeons Database: an analysis of surgical morbidity and mortality.
Burt, B. M., Cameron, R. B., Mollberg, N. M., Kosinski, A. S., Schipper, P. H., & Vigneswaran, W. T. (2014). Malignant pleural mesothelioma and the Society of Thoracic Surgeons Database: an analysis of surgical morbidity and mortality. journal of thoracic and cardiovascular surgery, 148(1), 30-35.
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A Meta-analysis of Lung Cancer Gene Expression Identifies PTK7 as a Survival Gene in Lung Adenocarcinoma
Chen, R., Khatri, P., Mazur, P. K., Polin, M., Zheng, Y., & Sweet-Cordero, E. A. (2014). A Meta-analysis of Lung Cancer Gene Expression Identifies PTK7 as a Survival Gene in Lung Adenocarcinoma. CANCER RESEARCH, 74(10), 2892-2902.
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An ultrasensitive method for quantitating circulating tumor DNA with broad patient coverage
Newman, A. M., Bratman, S. V., To, J., Wynne, J. F., Eclov, N. Cw., & Diehn, M. (2014). An ultrasensitive method for quantitating circulating tumor DNA with broad patient coverage. NATURE MEDICINE, 20(5), 552-558.
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miR-1 Induces Growth Arrest and Apoptosis in Malignant Mesothelioma
Xu, Y., Zheng, M., Merritt, R. E., Shrager, J. B., Wakelee, H. A., & Hoang, C. D. (2013). miR-1 Induces Growth Arrest and Apoptosis in Malignant Mesothelioma. CHEST, 144(5), 1632-1643.
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Lymph Node Evaluation Achieved by Open Lobectomy Compared With Thoracoscopic Lobectomy for N0 Lung Cancer
Merritt, R. E., Hoang, C. D., & Shrager, J. B. (2013). Lymph Node Evaluation Achieved by Open Lobectomy Compared With Thoracoscopic Lobectomy for N0 Lung Cancer. ANNALS OF THORACIC SURGERY, 96(4), 1171-1177.
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Liquid chromatography/mass spectrometry methods for measuring dipeptide abundance in non-small-cell lung cancer
Wu, M., Xu, Y., Fitch, W. L., Zheng, M., Merritt, R. E., & Hoang, C. D. (2013). Liquid chromatography/mass spectrometry methods for measuring dipeptide abundance in non-small-cell lung cancer. RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 27(18), 2091-2098.
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A Dominant Adenocarcinoma With Multifocal Ground Glass Lesions Does Not Behave as Advanced Disease
Gu, B., Burt, B. M., Merritt, R. E., Stephanie, S., Nair, V., & Shrager, J. B. (2013). A Dominant Adenocarcinoma With Multifocal Ground Glass Lesions Does Not Behave as Advanced Disease. ANNALS OF THORACIC SURGERY, 96(2), 411-418.
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Diaphragm muscle atrophy in the mouse after long-term mechanical ventilation
Tang, H., Lee, M., Khuong, A., Wright, E., & Shrager, J. B. (2013). Diaphragm muscle atrophy in the mouse after long-term mechanical ventilation. MUSCLE & NERVE, 48(2), 272-278.
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A Rare Population of CD24(+)ITGB4(+)Notch(hi) Cells Drives Tumor Propagation in NSCLC and Requires Notch3 for Self-Renewal
Zheng, Y., de la Cruz, C. C., Sayles, L. C., Alleyne-Chin, C., Vaka, D., & Sweet-Cordero, E. A. (2013). A Rare Population of CD24(+)ITGB4(+)Notch(hi) Cells Drives Tumor Propagation in NSCLC and Requires Notch3 for Self-Renewal. CANCER CELL, 24(1), 59-74.
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An Observational Study of Circulating Tumor Cells and F-18-FDG PET Uptake in Patients with Treatment-Naive Non-Small Cell Lung Cancer
Nair, V. S., Keu, K. V., Luttgen, M. S., Kolatkar, A., Vasanawala, M., & Kuhn, P. (2013). An Observational Study of Circulating Tumor Cells and F-18-FDG PET Uptake in Patients with Treatment-Naive Non-Small Cell Lung Cancer. PLOS ONE, 8(7).
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Approach to the Patient with Multiple Lung Nodules
Shrager, J. B. (2013). Approach to the Patient with Multiple Lung Nodules. THORACIC SURGERY CLINICS, 23(2), 257-?.
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Determinants of time to opioid cessation post-surgery
Ruchelli, G., Clay, D., Schmidt, P., Humphreys, K., Trafton, J., & Carroll, I. (2013). Determinants of time to opioid cessation post-surgery. JOURNAL OF PAIN, 14(4), S18-S18.
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An observational study of circulating tumor cells and (18)F-FDG PET uptake in patients with treatment-naive non-small cell lung cancer.
Nair, V. S., Keu, K. V., Luttgen, M. S., Kolatkar, A., Vasanawala, M., & Kuhn, P. (2013). An observational study of circulating tumor cells and (18)F-FDG PET uptake in patients with treatment-naive non-small cell lung cancer. PloS one, 8(7).
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Cross-Species Functional Analysis of Cancer-Associated Fibroblasts Identifies a Critical Role for CLCF1 and IL-6 in Non-Small Cell Lung Cancer In Vivo
Vicent, S., Sayles, L. C., Vaka, D., Khatri, P., Gevaert, O., & Sweet-Cordero, E. A. (2012). Cross-Species Functional Analysis of Cancer-Associated Fibroblasts Identifies a Critical Role for CLCF1 and IL-6 in Non-Small Cell Lung Cancer In Vivo. CANCER RESEARCH, 72(22), 5744-5756.
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Oxidative stress-responsive microRNA-320 regulates glycolysis in diverse biological systems
Tang, H., Lee, M., Sharpe, O., Salamone, L., Noonan, E. J., & Shrager, J. B. (2012). Oxidative stress-responsive microRNA-320 regulates glycolysis in diverse biological systems. FASEB JOURNAL, 26(11), 4710-4721.
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Indications for Surgery in Patients with Localized Pulmonary Infection
Merritt, R. E., & Shrager, J. B. (2012). Indications for Surgery in Patients with Localized Pulmonary Infection. THORACIC SURGERY CLINICS, 22(3), 325-?.
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Prognostic PET F-18-FDG Uptake Imaging Features Are Associated with Major Oncogenomic Alterations in Patients with Resected Non-Small Cell Lung Cancer
Nair, V. S., Gevaert, O., Davidzon, G., Napel, S., Graves, E. E., & Plevritis, S. K. (2012). Prognostic PET F-18-FDG Uptake Imaging Features Are Associated with Major Oncogenomic Alterations in Patients with Resected Non-Small Cell Lung Cancer. CANCER RESEARCH, 72(15), 3725-3734.
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Invited commentary.
Shrager, J. B. (2012). Invited commentary. Annals of thoracic surgery, 94(1), 240-?.
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Prophylaxis and Management of Atrial Fibrillation After General Thoracic Surgery
Merritt, R. E., & Shrager, J. B. (2012). Prophylaxis and Management of Atrial Fibrillation After General Thoracic Surgery. THORACIC SURGERY CLINICS, 22(1), 13-?.
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Invited commentary.
Shrager, J. B. (2011). Invited commentary. Annals of thoracic surgery, 92(6), 2005-2006.
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Morbidity and Mortality After Esophagectomy Following Neoadjuvant Chemoradiation
Merritt, R. E., Whyte, R. I., D'Arcy, N. T., Hoang, C. D., & Shrager, J. B. (2011). Morbidity and Mortality After Esophagectomy Following Neoadjuvant Chemoradiation. ANNALS OF THORACIC SURGERY, 92(6), 2034-2040.
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Benign emptying of the postpneumonectomy space.
Merritt, R. E., Reznik, S. I., DaSilva, M. C., Sugarbaker, D. J., Whyte, R. I., & Shrager, J. B. (2011). Benign emptying of the postpneumonectomy space. Annals of thoracic surgery, 92(3), 1076-1081.
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Intrinsic apoptosis in mechanically ventilated human diaphragm: linkage to a novel Fos/FoxO1/Stat3-Bim axis
Tang, H., Lee, M., Budak, M. T., Pietras, N., Hittinger, S., & Shrager, J. B. (2011). Intrinsic apoptosis in mechanically ventilated human diaphragm: linkage to a novel Fos/FoxO1/Stat3-Bim axis. FASEB JOURNAL, 25(9), 2921-2936.
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Tumor Volume as a Potential Imaging-Based Risk-Stratification Factor in Trimodality Therapy for Locally Advanced Non-small Cell Lung Cancer
Kozak, M. M., Murphy, J. D., Schipper, M. L., Donington, J. S., Zhou, L., & Loo, B. W. (2011). Tumor Volume as a Potential Imaging-Based Risk-Stratification Factor in Trimodality Therapy for Locally Advanced Non-small Cell Lung Cancer. JOURNAL OF THORACIC ONCOLOGY, 6(5), 920-926.
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Improved Survival after Pulmonary Metastasectomy for Soft Tissue Sarcoma
Predina, J. D., Puc, M. M., Bergey, M. R., Sonnad, S. S., Kucharczuk, J. C., & Shrager, J. B. (2011). Improved Survival after Pulmonary Metastasectomy for Soft Tissue Sarcoma. JOURNAL OF THORACIC ONCOLOGY, 6(5), 913-919.
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Invited commentary.
Shrager, J. B. (2010). Invited commentary. Annals of thoracic surgery, 90(6), 1785-?.
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Should buttresses and sealants be used to manage pulmonary parenchymal air leaks?
Singhal, S., & Shrager, J. B. (2010). Should buttresses and sealants be used to manage pulmonary parenchymal air leaks?. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 140(6), 1220-1225.
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Evidence-based suggestions for management of air leaks.
Merritt, R. E., Singhal, S., & Shrager, J. B. (2010). Evidence-based suggestions for management of air leaks. Thoracic surgery clinics, 20(3), 435-448.
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Extended Transcervical Thymectomy: The Ultimate Minimally Invasive Approach
Shrager, J. B. (2010). Extended Transcervical Thymectomy: The Ultimate Minimally Invasive Approach. ANNALS OF THORACIC SURGERY, 89(6), S2128-S2134.
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Mediastinoscopy: Still the Gold Standard
Shrager, J. B. (2010). Mediastinoscopy: Still the Gold Standard. ANNALS OF THORACIC SURGERY, 89(6), S2084-S2089.
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METABOLOMIC PROFILING OF LUNG ADENOCARCINOMA
Hoang, C. D., Wu, M., Xu, Y., Peltz, G., Merritt, R., & Shrager, J. (2010). METABOLOMIC PROFILING OF LUNG ADENOCARCINOMA. JOURNAL OF THORACIC ONCOLOGY, 5(5), S51-S52.
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MULTIPLE MICRORNA ARE DYSREGULATED IN MESOTHELIOMA
Hoang, C. D., Xu, Y., Zheng, M., Peltz, G., Shrager, J., & Kratzke, R. (2010). MULTIPLE MICRORNA ARE DYSREGULATED IN MESOTHELIOMA. JOURNAL OF THORACIC ONCOLOGY, 5(5), S105-S106.
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Adjuvant Cisplatin and Docetaxel for Non-small Cell Lung Cancer The Hospital of the University of Pennsylvania Experience
Weiss, J., Eaby, B., Stevenson, J., Kucharczuk, J., Cooper, J., & Evans, T. (2010). Adjuvant Cisplatin and Docetaxel for Non-small Cell Lung Cancer The Hospital of the University of Pennsylvania Experience. JOURNAL OF THORACIC ONCOLOGY, 5(5), 667-672.
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Management of Alveolar Air Leaks After Pulmonary Resection
Singhal, S., Ferraris, V. A., Bridges, C. R., Clough, E. R., Mitchell, J. D., & Shrager, J. B. (2010). Management of Alveolar Air Leaks After Pulmonary Resection. ANNALS OF THORACIC SURGERY, 89(4), 1327-1335.
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Early outcomes after bilateral thoracoscopy versus median sternotomy for lung volume reduction.
Puc, M. M., Sonnad, S. S., & Shrager, J. B. (2010). Early outcomes after bilateral thoracoscopy versus median sternotomy for lung volume reduction. Innovations (Philadelphia, Pa.), 5(2), 97-102.
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The Society of Thoracic Surgeons Practice Guideline Series: Guidelines for the Management of Barrett's Esophagus With High-Grade Dysplasia
Fernando, H. C., Murthy, S. C., Hofstetter, W., Shrager, J. B., Bridges, C., & Watson, T. J. (2009). The Society of Thoracic Surgeons Practice Guideline Series: Guidelines for the Management of Barrett's Esophagus With High-Grade Dysplasia. ANNALS OF THORACIC SURGERY, 87(6), 1993-2002.
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Intraoperative and postoperative management of air leaks in patients with emphysema.
Shrager, J. B., DeCamp, M. M., & Murthy, S. C. (2009). Intraoperative and postoperative management of air leaks in patients with emphysema. Thoracic surgery clinics, 19(2), 223-?.
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Thymoma
Shrager, J. B. (2009). Thymoma. ANNALS OF THORACIC SURGERY, 87(1), 339-341.
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Thoracoscopic total parietal pleurectomy for primary spontaneous pneumothorax
Nathan, D. P., Taylor, N. E., Low, D. W., Raymond, D., & Shrager, J. B. (2008). Thoracoscopic total parietal pleurectomy for primary spontaneous pneumothorax. ANNALS OF THORACIC SURGERY, 85(5), 1825-1827.
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Rapid disuse atrophy of diaphragm fibers in mechanically ventilated humans
Levine, S., Nguyen, T., Taylor, N., Friscia, M. E., Budak, M. T., & Shrager, J. B. (2008). Rapid disuse atrophy of diaphragm fibers in mechanically ventilated humans. NEW ENGLAND JOURNAL OF MEDICINE, 358(13), 1327-1335.
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Early changes of lung function and structure in an elastase model of emphysema - a hyperpolarized He-3 MRI study
Emami, K., Cadman, R. V., Woodburn, J. M., Fischer, M. C., Kadlecek, S. J., & Rizi, R. R. (2008). Early changes of lung function and structure in an elastase model of emphysema - a hyperpolarized He-3 MRI study. JOURNAL OF APPLIED PHYSIOLOGY, 104(3), 773-786.
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Extended transcervical thymectomy in the treatment of myasthenia gravis
Khicha, S. G., Kaiser, L. R., & Shrager, J. B. (2008). Extended transcervical thymectomy in the treatment of myasthenia gravis. MYASTHENIA GRAVIS AND RELATED DISORDERS: 11TH INTERNATIONAL CONFERENCE, 1132, 336-343.
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Complications of video-assisted thoracoscopic lung biopsy in patients with interstitial lung disease
Kreider, M. E., Hansen-Flaschen, J., Ahmad, N. N., Rossman, M. D., Kaiser, L. R., & Shrager, J. B. (2007). Complications of video-assisted thoracoscopic lung biopsy in patients with interstitial lung disease. ANNALS OF THORACIC SURGERY, 83(3), 1140-1145.
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Cytokine response is lower after lung volume reduction through bilateral thoracoscopy versus sternotomy
Friscia, M. E., Zhu, J., Kolff, J. W., Chen, Z., Kaiser, L. R., & Shrager, J. B. (2007). Cytokine response is lower after lung volume reduction through bilateral thoracoscopy versus sternotomy. ANNALS OF THORACIC SURGERY, 83(1), 252-256.
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Parasternal intercostal muscle remodeling in severe chronic obstructive pulmonary disease
Levine, S., Nguyen, T., Friscia, M., Zhu, J., Szeto, W., & Shrager, J. B. (2006). Parasternal intercostal muscle remodeling in severe chronic obstructive pulmonary disease. JOURNAL OF APPLIED PHYSIOLOGY, 101(5), 1297-1302.
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Outcomes after 151 extended transcervical thymectomies for myasthenia gravis
Shrager, J. B., Nathan, D., Brinster, C. J., Yousuf, O., Spence, A., & Kaiser, L. R. (2006). Outcomes after 151 extended transcervical thymectomies for myasthenia gravis. ANNALS OF THORACIC SURGERY, 82(5), 1863-1869.
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Anterior surgical approaches to the thoracic outlet
Marshall, M. B., Kucharczuk, J. C., Shrager, J. B., & Kaiser, L. R. (2006). Anterior surgical approaches to the thoracic outlet. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 131(6), 1255-1260.
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Invited commentary.
Shrager, J. B. (2006). Invited commentary. Annals of thoracic surgery, 81(1), 334-?.
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Comparative study of subxiphoid versus video-thoracoscopic pericardial "'window"
O'Brien, P. Kh., Kucharczuk, J. C., Marshall, M. B., Friedberg, J. S., Chen, Z., & Shrager, J. B. (2005). Comparative study of subxiphoid versus video-thoracoscopic pericardial "'window". ANNALS OF THORACIC SURGERY, 80(6), 2013-2019.
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Pain and physical function are similar following axillary, muscle-sparing vs posterolateral thoracotomy
Ochroch, E. A., Gottschalk, A., Augoustides, J. G., Aukburg, S. J., Kaiser, L. R., & Shrager, J. B. (2005). Pain and physical function are similar following axillary, muscle-sparing vs posterolateral thoracotomy. CHEST, 128(4), 2664-2670.
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Effect of chronic obstructive pulmonary disease on calcium pump ATPase expression in human diaphragm
Nguyen, T., Rubinstein, N. A., Vijayasarathy, C., Rome, L. C., Kaiser, L. R., & Levine, S. (2005). Effect of chronic obstructive pulmonary disease on calcium pump ATPase expression in human diaphragm. JOURNAL OF APPLIED PHYSIOLOGY, 98(6), 2004-2010.
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Quantitative assessment of emphysema using hyperpolarized He-3 magnetic resonance imaging
Spector, Z. Z., Emami, K., Fischer, M. C., Zhu, J., Ishii, M., & Rizi, R. R. (2005). Quantitative assessment of emphysema using hyperpolarized He-3 magnetic resonance imaging. MAGNETIC RESONANCE IN MEDICINE, 53(6), 1341-1346.
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Which patients with stage III non-small cell lung cancer should undergo surgical resection?
Patel, V., & Shrager, J. B. (2005). Which patients with stage III non-small cell lung cancer should undergo surgical resection?. ONCOLOGIST, 10(5), 335-344.
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Catamenial pneumothorax: optimal hormonal and surgical management
Marshall, M. B., Ahmed, Z., Kucharczuk, J. C., Kaiser, L. R., & Shrager, J. B. (2005). Catamenial pneumothorax: optimal hormonal and surgical management. EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY, 27(4), 662-666.
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Hyperpolarized helium-3 MR imaging of pulmonary function
Ishii, M., Fischer, M. C., Emami, K., Alavi, A., Spector, Z. Z., & Rizi, R. R. (2005). Hyperpolarized helium-3 MR imaging of pulmonary function. RADIOLOGIC CLINICS OF NORTH AMERICA, 43(1), 235-?.
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A small animal model of regional alveolar ventilation using (HPHe)-He-3 MRI
Spector, Z. Z., Emami, K., Fischer, M. C., Zhu, J., Ishii, M., & Rizi, R. R. (2004). A small animal model of regional alveolar ventilation using (HPHe)-He-3 MRI. ACADEMIC RADIOLOGY, 11(10), 1171-1179.
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Lung cancer in transplant recipients - A single-institution experience
Ahmed, Z., Marshall, M. B., Kucharczuk, J. C., Kaiser, L. R., & Shrager, J. B. (2004). Lung cancer in transplant recipients - A single-institution experience. ARCHIVES OF SURGERY, 139(8), 902-906.
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Myosin gene mutation correlates with anatomical changes in the human lineage
Stedman, H. H., Kozyak, B. W., Nelson, A., Thesier, D. M., Su, L. T., & Mitchell, M. A. (2004). Myosin gene mutation correlates with anatomical changes in the human lineage. NATURE, 428(6981), 415-418.
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Two commonly used neoadjuvant chemoradiotherapy regimens for locally advanced stage III non-small cell lung carcinoma: Long-term results and associations with pathologic response
Machtay, M., Lee, J. H., Stevenson, J. P., Shrager, J. B., Algazy, K. M., & Kaiser, L. R. (2004). Two commonly used neoadjuvant chemoradiotherapy regimens for locally advanced stage III non-small cell lung carcinoma: Long-term results and associations with pathologic response. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 127(1), 108-113.
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Comparison of stages I-II thymoma treated by complete resection with or without adjuvant radiation
Singhal, S., Shrager, J. B., Rosenthal, D. I., LiVolsi, V. A., & Kaiser, L. R. (2003). Comparison of stages I-II thymoma treated by complete resection with or without adjuvant radiation. ANNALS OF THORACIC SURGERY, 76(5), 1635-1641.
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Human diaphragm remodeling associated with chronic obstructive pulmonary disease - Clinical implications
Levine, S., Nguyen, T., Kaiser, L. R., Rubinstein, N. A., Maislin, G., & Shrager, J. B. (2003). Human diaphragm remodeling associated with chronic obstructive pulmonary disease - Clinical implications. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 168(6), 706-713.
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Tracheal trauma.
Shrager, J. B. (2003). Tracheal trauma. Chest surgery clinics of North America, 13(2), 291-304.
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Omentum is highly effective in the management of complex cardiothoracic surgical problems
Shrager, J. B., Wain, J. C., Wright, C. D., Donahue, D. M., Vlahakes, G. J., & Mathisen, D. J. (2003). Omentum is highly effective in the management of complex cardiothoracic surgical problems. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 125(3), 526-532.
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Myosin heavy chain and physiological adaptation of the rat diaphragm in elastase-induced emphysema
Kim, D. K., Zhu, J. L., Kozyak, B. W., Burkman, J. M., Rubinstein, N. A., & Shrager, J. B. (2003). Myosin heavy chain and physiological adaptation of the rat diaphragm in elastase-induced emphysema. RESPIRATORY RESEARCH, 4(1).
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Inspiratory loading does not accelerate dystrophy in mdx mouse diaphragm: implications for regenerative therapy
Krupnick, A. S., Zhu, J. L., Nguyen, T., Kreisel, D., Balsara, K. R., & Shrager, J. B. (2003). Inspiratory loading does not accelerate dystrophy in mdx mouse diaphragm: implications for regenerative therapy. JOURNAL OF APPLIED PHYSIOLOGY, 94(2), 411-419.
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Mediastinal talcoma masquerading as thymoma
Ahmed, Z., & Shrager, J. B. (2003). Mediastinal talcoma masquerading as thymoma. ANNALS OF THORACIC SURGERY, 75(2), 568-569.
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Evaluating respiratory muscle adaptations - A new approach
LEVINE, S., Nguyen, T., Kaiser, L. R., & Shrager, J. B. (2002). Evaluating respiratory muscle adaptations - A new approach. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 166(11), 1418-1419.
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Benign expectoration of a surgical clip through a pneumonectomy stump
Ahmed, Z., Kaiser, L. R., & Shrager, J. B. (2002). Benign expectoration of a surgical clip through a pneumonectomy stump. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 124(5), 1025-1026.
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Transcervical thymectomy for myasthenia gravis achieves results comparable to thymectomy by sternotomy
Shrager, J. B., Deeb, M. E., Mick, R., Brinster, C. J., Childers, H. E., & Kaiser, L. R. (2002). Transcervical thymectomy for myasthenia gravis achieves results comparable to thymectomy by sternotomy. ANNALS OF THORACIC SURGERY, 74(2), 320-326.
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Pathological response to preoperative chemoradiation worsens with anemia in non-small cell lung cancer patients
Robnett, T. J., Machtay, M., Hahn, S. M., Shrager, J. B., Freidberg, J. S., & Kaiser, L. R. (2002). Pathological response to preoperative chemoradiation worsens with anemia in non-small cell lung cancer patients. CANCER JOURNAL, 8(3), 263-267.
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Evolutionary implications of three novel members of the human sarcomeric myosin heavy chain gene family
Desjardins, P. R., Burkman, J. M., Shrager, J. B., Allmond, L. A., & Stedman, H. H. (2002). Evolutionary implications of three novel members of the human sarcomeric myosin heavy chain gene family. MOLECULAR BIOLOGY AND EVOLUTION, 19(4), 375-393.
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Suction vs water seal after pulmonary resection - A randomized prospective study
Marshall, M. B., Deeb, M. E., Bleier, J. Is., Kucharczuk, J. C., Friedberg, J. S., & Shrager, J. B. (2002). Suction vs water seal after pulmonary resection - A randomized prospective study. CHEST, 121(3), 831-835.
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Current presentation and optimal surgical management of sternoclavicular joint infections
Song, H. K., Guy, T. S., Kaiser, L. R., & Shrager, J. B. (2002). Current presentation and optimal surgical management of sternoclavicular joint infections. ANNALS OF THORACIC SURGERY, 73(2), 427-431.
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Sarcomeres are added in series to emphysematous rat diaphragm after lung volume reduction surgery
Shrager, J. B., Kim, D. K., Hashmi, Y. J., Stedman, H. H., Zhu, J. L., & LEVINE, S. (2002). Sarcomeres are added in series to emphysematous rat diaphragm after lung volume reduction surgery. CHEST, 121(1), 210-215.
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Osteogenic sarcoma presenting with lung metastasis
Staddon, A. P., Lackman, R., Robinson, K., Shrager, J. B., & Warhol, M. (2002). Osteogenic sarcoma presenting with lung metastasis. ONCOLOGIST, 7(2), 144-153.
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Risk of death from intercurrent disease is not excessively increased by modern postoperative radiotherapy for high-risk resected non-small-cell lung carcinoma
Machtay, M., Lee, J. H., Shrager, J. B., Kaiser, L. R., & Glatstein, E. (2001). Risk of death from intercurrent disease is not excessively increased by modern postoperative radiotherapy for high-risk resected non-small-cell lung carcinoma. JOURNAL OF CLINICAL ONCOLOGY, 19(19), 3912-3917.
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Successful-experience with simultaneous lung volume reduction and cardiac procedures
Shrager, J. B., Kozyak, B. W., Roberts, J. R., Bavaria, J. E., Friedberg, J. S., & Rosengard, B. R. (2001). Successful-experience with simultaneous lung volume reduction and cardiac procedures. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 122(1), 196-197.
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Expanded indications for transcervical thymectomy in the management of anterior mediastinal masses
Deeb, M. E., Brinster, C. J., Kucharzuk, J., Shrager, J. B., & Kaiser, L. R. (2001). Expanded indications for transcervical thymectomy in the management of anterior mediastinal masses. ANNALS OF THORACIC SURGERY, 72(1), 208-211.
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Bronchial anastomotic stricture caused by ossification of an intercostal muscle flap
Deeb, M. E., Sterman, D. H., Shrager, J. B., & Kaiser, L. R. (2001). Bronchial anastomotic stricture caused by ossification of an intercostal muscle flap. ANNALS OF THORACIC SURGERY, 71(5), 1700-1702.
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Lung volume reduction surgery restores the normal diaphragmatic length-tension relationship in emphysematous rats
Shrager, J. B., Kim, D. K., Hashmi, Y. J., Lankford, E. B., Wahl, P., & Kaiser, L. R. (2001). Lung volume reduction surgery restores the normal diaphragmatic length-tension relationship in emphysematous rats. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 121(2), 217-224.
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Lobectomy with tangential pulmonary artery resection without regard to pulmonary function
Shrager, J. B., Lambright, E. S., McGrath, C. M., Wahl, P. M., Deeb, M. E., & Kaiser, L. R. (2000). Lobectomy with tangential pulmonary artery resection without regard to pulmonary function. ANNALS OF THORACIC SURGERY, 70(1), 234-239.
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Human skeletal myosin heavy chain genes are tightly linked in the order embryonic-IIa-IId/x-IIb-perinatal-extraocular
Shrager, J. B., Desjardins, P. R., Burkman, J. M., Konig, S. K., Stewart, D. R., & Stedman, H. H. (2000). Human skeletal myosin heavy chain genes are tightly linked in the order embryonic-IIa-IId/x-IIb-perinatal-extraocular. JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY, 21(4), 345-355.
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Lung volume reduction surgery.
Shrager, J. B., Kaiser, L. R., & Edelman, J. D. (2000). Lung volume reduction surgery. Current problems in surgery, 37(4), 253-317.
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Lymphangioleiomyomatosis: The surgeon's role in diagnosis
Deeb, M., Shrager, J. B., Edelman, J. D., & Kaiser, L. (2000). Lymphangioleiomyomatosis: The surgeon's role in diagnosis. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 119(3), 622-623.
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Thoracoscopic lung biopsy - Five commonly asked questions about video-assisted thoracic surgery
Shrager, J. B., & Kaiser, L. R. (1999). Thoracoscopic lung biopsy - Five commonly asked questions about video-assisted thoracic surgery. POSTGRADUATE MEDICINE, 106(4), 139-?.
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Bronchopulmonary carcinoid tumors associated with Cushing's syndrome: A more aggressive variant of typical carcinoid
Shrager, J. B., Wright, C. D., Wain, J. C., Torchiana, D. F., Grillo, H. C., & Mathisen, D. J. (1997). Bronchopulmonary carcinoid tumors associated with Cushing's syndrome: A more aggressive variant of typical carcinoid. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 114(3), 367-375.
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Treatment of refractory, nonmalignant hydrothorax with a pleurovenous shunt
Park, S. Z., Shrager, J. B., Allen, M. S., & Nagorney, D. M. (1997). Treatment of refractory, nonmalignant hydrothorax with a pleurovenous shunt. ANNALS OF THORACIC SURGERY, 63(6), 1777-1779.
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VIDEO-ASSISTED THORACIC-SURGERY - THE CURRENT STATE-OF-THE-ART
Kaiser, L. R., & Shrager, J. B. (1995). VIDEO-ASSISTED THORACIC-SURGERY - THE CURRENT STATE-OF-THE-ART. AMERICAN JOURNAL OF ROENTGENOLOGY, 165(5), 1111-1117.
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VILLOUS ADENOMA OF THE MAIN PANCREATIC DUCT - A CLUE TO THE PATHOGENESIS OF PANCREATIC MALIGNANCY
Shrager, J. B., GREELISH, J., VANARSDALE, C., Furth, E., & Daly, J. M. (1994). VILLOUS ADENOMA OF THE MAIN PANCREATIC DUCT - A CLUE TO THE PATHOGENESIS OF PANCREATIC MALIGNANCY. SURGICAL ONCOLOGY-OXFORD, 3(4), 203-210.
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THE VINEBERG PROCEDURE - THE IMMEDIATE FORERUNNER OF CORONARY-ARTERY BYPASS-GRAFTING
Shrager, J. B. (1994). THE VINEBERG PROCEDURE - THE IMMEDIATE FORERUNNER OF CORONARY-ARTERY BYPASS-GRAFTING. ANNALS OF THORACIC SURGERY, 57(5), 1354-1364.
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ADAPTATIONS IN MYOSIN HEAVY-CHAIN EXPRESSION AND CONTRACTILE FUNCTION IN DYSTROPHIC MOUSE DIAPHRAGM
Petrof, B. J., Stedman, H. H., Shrager, J. B., Eby, J., Sweeney, H. L., & Kelly, A. M. (1993). ADAPTATIONS IN MYOSIN HEAVY-CHAIN EXPRESSION AND CONTRACTILE FUNCTION IN DYSTROPHIC MOUSE DIAPHRAGM. AMERICAN JOURNAL OF PHYSIOLOGY, 265(3), C834-C841.
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DYSTROPHIN PROTECTS THE SARCOLEMMA FROM STRESSES DEVELOPED DURING MUSCLE-CONTRACTION
Petrof, B. J., Shrager, J. B., Stedman, H. H., Kelly, A. M., & Sweeney, H. L. (1993). DYSTROPHIN PROTECTS THE SARCOLEMMA FROM STRESSES DEVELOPED DURING MUSCLE-CONTRACTION. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 90(8), 3710-3714.
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A PCR-BASED ASSAY FOR THE WILD-TYPE DYSTROPHIN GENE TRANSFERRED INTO THE MDX MOUSE
Shrager, J. B., Naji, A., Kelly, A. M., & Stedman, H. H. (1992). A PCR-BASED ASSAY FOR THE WILD-TYPE DYSTROPHIN GENE TRANSFERRED INTO THE MDX MOUSE. MUSCLE & NERVE, 15(10), 1133-1137.
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3 WOMEN AT JOHNS-HOPKINS - PRIVATE PERSPECTIVES ON MEDICAL COEDUCATION IN THE 1890S
Shrager, J. B. (1991). 3 WOMEN AT JOHNS-HOPKINS - PRIVATE PERSPECTIVES ON MEDICAL COEDUCATION IN THE 1890S. ANNALS OF INTERNAL MEDICINE, 115(7), 564-569.
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THE MDX MOUSE DIAPHRAGM REPRODUCES THE DEGENERATIVE CHANGES OF DUCHENNE MUSCULAR-DYSTROPHY
Stedman, H. H., Sweeney, H. L., Shrager, J. B., Maguire, H. C., Panettieri, R. A., & Kelly, A. M. (1991). THE MDX MOUSE DIAPHRAGM REPRODUCES THE DEGENERATIVE CHANGES OF DUCHENNE MUSCULAR-DYSTROPHY. NATURE, 352(6335), 536-539.
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Patient Comments
Patients comments are gathered from our Patient Satisfaction Survey and displayed in their entirety. Patients are de-identified for confidentiality and patient privacy.
SHC Patient, Sep 2015
Everyone is very conscientious! Actual time seeing doctor felt rushed.
SHC Patient, Jul 2015
Excellent.
SHC Patient, Jun 2015
I was weak from surgery & needed more specific advise about how to heal more quickly & did not get that. However. Dr. Shrager did a great job with surgery & referred me to Dr. Heather Walker.
SHC Patient, May 2015
Wanted more info about 2 spots on my lung -> New or old & seen before now?
SHC Patient, May 2015
Dr. Shrager, is an excellent thoracic surgeon. May God keep blessing him in his noble work!
SHC Patient, May 2015
I would definitely recommend it!
SHC Patient, Mar 2015
Excellent.
SHC Patient, Feb 2015
Dr. Shrager an excellent surgeon - brisk and to the point.
SHC Patient, Jan 2015
The entire experience was VERY positive.
SHC Patient, Dec 2014
Excellent.
SHC Patient, Dec 2014
Dr. Shrager is an excellent doctor!
SHC Patient, Oct 2014
The best provider. He is #1.
SHC Patient, Sep 2014
I could have been more aware of what I needed to know. My first surgery hospital stay in 50+ years I was not knowledgeable of hospital protocol.
SHC Patient, Sep 2014
Dr. Shrager & staff offer superior care and I feel very fortunate to have had him as my surgeon. Everything about his clinic is top-notch and he really cares about his patients but also provides the best care possible.
SHC Patient, Jul 2014
Limited experience with ACC cancer. Some of his comments went against what I know of the disease.
SHC Patient, May 2014
Dr. Shrager is an excellent doctor and I feel very fortunate to be his patient.
SHC Patient, May 2014
Staff was outstanding and very helpful as well as available.
SHC Patient, May 2014
Excellent - professional - gave me confidence that I was in the best hands.
SHC Patient, Mar 2014
The intern was so informative and Dr. Shrager told me more than I have been able to understand and answered questions - than I have in the last several months of my dr. in home town.
SHC Patient, Dec 2013
Excellent doctor in MANY ways!! I did feel slightly rushed in my last visit though.
SHC Patient, Sep 2015
Everyone is very conscientious! Actual time seeing doctor felt rushed.
SHC Patient, Jul 2015
Excellent.
SHC Patient, Jun 2015
I was weak from surgery & needed more specific advise about how to heal more quickly & did not get that. However. Dr. Shrager did a great job with surgery & referred me to Dr. Heather Walker.
SHC Patient, May 2015
Wanted more info about 2 spots on my lung -> New or old & seen before now?
SHC Patient, May 2015
Dr. Shrager, is an excellent thoracic surgeon. May God keep blessing him in his noble work!
SHC Patient, May 2015
I would definitely recommend it!
SHC Patient, Mar 2015
Excellent.
SHC Patient, Feb 2015
Dr. Shrager an excellent surgeon - brisk and to the point.
SHC Patient, Jan 2015
The entire experience was VERY positive.
SHC Patient, Dec 2014
Excellent.
SHC Patient, Dec 2014
Dr. Shrager is an excellent doctor!
SHC Patient, Oct 2014
The best provider. He is #1.
View All 20 Patient Comments »