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Laparotomy vs. Drainage for Infants With Necrotizing Enterocolitis
This trial will compare the effectiveness of two surgical procedures -laparotomy versus
drainage - commonly used to treat necrotizing enterocolitis (NEC) or isolated intestinal
perforations (IP) in extremely low birth weight infants (≤1,000 g). Infants diagnosed with
NEC or IP requiring surgical intervention, will be recruited. Subjects will be randomized to
receive either a laparotomy or peritoneal drainage. Primary outcome is impairment-free
survival at 18-22 months corrected age.
Principal Investigator
- Krisa Van Meurs
Stanford Investigator(s)
- David K. Stevenson, M.D.
- Susan R. Hintz, M.D., M.S. Epi.
- Karl Sylvester