Personalization in practice

See allHide authors and affiliations

Science  16 Oct 2015:
Vol. 350, Issue 6258, pp. 282-283
DOI: 10.1126/science.aad5204

You are currently viewing the summary.

View Full Text

Log in to view the full text

Log in through your institution

Log in through your institution


Last month, an advisory committee released recommendations for recruiting at least 1 million individuals to participate in the U.S. National Institutes of Health's Precision Medicine Initiative. This bold approach to disease treatment and prevention seeks to account for an individual's genes, environment, and lifestyle to improve health outcomes. The ability to collect, integrate, analyze, and model relevant data streams is central to this effort. Moving beyond “just” massive data collection will require structured convergence among various disciplines. So, how should data be gathered? Here, computational modeling can be a useful guide. Modeling at the molecular, cellular, tissue, and organismal level will be essential to identify the molecular interactions that underlie progressive diseases and to generate a comprehensive and dynamic picture of the individual.