CSB 199: Undergraduate Research
Students undertake investigations sponsored by individual faculty members. Prerequisite: consent of instructor.
Terms: Aut, Win, Spr, Sum
|
Units: 1-18
|
Repeatable for credit
|
Grading: Satisfactory/No Credit
Instructors:
Chen, J. (PI)
;
Cimprich, K. (PI)
;
Elias, J. (PI)
;
Ferrell, J. (PI)
...
more instructors for CSB 199 »
Instructors:
Chen, J. (PI)
;
Cimprich, K. (PI)
;
Elias, J. (PI)
;
Ferrell, J. (PI)
;
Jarosz, D. (PI)
;
Meyer, T. (PI)
;
Mochly-Rosen, D. (PI)
;
Teruel, M. (PI)
;
Wandless, T. (PI)
;
Wysocka, J. (PI)
CSB 210: Cell Signalling
The molecular mechanisms through which cells receive and respond to external signals. Emphasis is on principles of cell signaling, the systems-level properties of signal transduction modules, and experimental strategies through which cell signaling pathways are being studied. Prerequisite: working knowledge of biochemistry and genetics.
Terms: Win
|
Units: 4
|
Grading: Medical Option (Med-Ltr-CR/NC)
CSB 220: Chemistry of Biological Processes (BIOC 220)
The principles of organic and physical chemistry as applied to biomolecules. Goal is a working knowledge of chemical principles that underlie biological processes, and chemical tools used to study and manipulate biological systems. Prerequisites: organic chemistry and biochemistry, or consent of instructor.
Terms: not given this year
|
Units: 4
|
Grading: Medical Option (Med-Ltr-CR/NC)
CSB 230: Current Methods in Proteomics
Introduces students to the instrumentation, experimental strategies, and computational methods used for identification and quantification of protein concentrations and posttranslational modifications on a systems-wide level. Topics include mass spectrometry (instrumentation configurations; polypeptide ionization; sample preparation and fractionation techniques; mass spectra interpretation; relative and absolute protein quantitation; and proteome-scale dataset analysis), protein and antibody arrays, multiparameter flow cytometry with Bayesian analysis, ribosomal protein translation profiling, and GFP and fluorescence imaging based quantification of protein abundance and post-translational modifications.
Terms: alternate years, given next year
|
Units: 3
|
Grading: Medical Option (Med-Ltr-CR/NC)
CSB 240A: A Practical Approach to Drug Discovery and Development
Advancing a drug from discovery of a therapeutic target to human trials and commercialization. Topics include: high throughput assay development, compound screening, lead optimization, protecting intellectual property, toxicology testing, regulatory issues, assessment of clinical need, defining the market, conducting clinical trials, project management, and commercialization issues, including approach to licensing and raising capital. Maximum units are available by taking an additional contact hour.
Terms: Win
|
Units: 3-4
|
Grading: Medical Option (Med-Ltr-CR/NC)
Instructors:
Grimes, K. (PI)
;
Mochly-Rosen, D. (PI)
CSB 240B: A Practical Approach to Drug Discover and Development
(Continuation of 240A) Advancing a drug from discovery of a therapeutic target to human trials and commercialization. Topics include: high throughput assay development, compound screening, lead optimization, protecting intellectual property, toxicology testing, regulatory issues, assessment of clinical need, defining the market, conducting clinical trials, project management, and commercialization issues, including approach to licensing and raising capital. Maximum units are available by taking an additional contact hour. Prerequisite: 240A.
Terms: Spr
|
Units: 3-4
|
Grading: Medical Option (Med-Ltr-CR/NC)
Instructors:
Grimes, K. (PI)
;
Mochly-Rosen, D. (PI)
CSB 242: Drug Discovery and Development Seminar Series
The scientific principles and technologies involved in making the transition from a basic biological observation to the creation of a new drug emphasizing molecular and genetic issues. Prerequisite: biochemistry, chemistry, or bioengineering.
Terms: Win, Spr
|
Units: 1
|
Repeatable for credit
|
Grading: Medical Satisfactory/No Credit
Instructors:
Grimes, K. (PI)
;
Mochly-Rosen, D. (PI)
CSB 244: Drug Discovery and Development: A Case-based Approach
Introductory course covering the basics of drug discovery and development. Topics include target identification and validation; identification of small molecule compounds that modulate the target of interest; properties of a drug development candidate; drug formulation, absorption, and pharmacokinetics; preclinical safety studies; drug manufacturing and quality assurance; human testing for safety and efficacy; and regulatory issues. Chemical and Systems Biology students may not take this class for credit in addition to
CSB 240A.
Terms: alternate years, given next year
|
Units: 3
|
Grading: Medical Option (Med-Ltr-CR/NC)
CSB 250: The Biology of Chromatin Templated Processes
Topics include mechanisms of DNA replication; gene expressions regulation; DNA damage sensing and DNA repair; chromatin structure and function; and epigenetics and nuclear reprogramming. Prerequisite: working knowledge of molecular biology, biochemistry and genetics, or instructor consent.
Terms: Spr
|
Units: 3
|
Grading: Letter (ABCD/NP)
Instructors:
Cimprich, K. (PI)
;
Wysocka, J. (PI)
CSB 260: Concepts and Applications in Chemical Biology
Current topics include chemical genetics, activity-based probes, inducible protein degradation, DNA/RNA chemistry and molecular evolution, protein labeling, carbohydrate engineering, fluorescent proteins and sensors, optochemical/optogenetic methods, mass spectrometry, and genome-editing technologies.
Terms: alternate years, given next year
|
Units: 4
|
Grading: Letter or Credit/No Credit
Filter Results: