Required Pre-Clerkship Curriculum

BIOC 205: Molecular Foundations of Medicine

Topics include DNA structure, replication, repair, and recombination; gene expression, including mechanisms for regulating transcription and translation; chromosome structure and function; gene cloning, protein engineering, and genomics. Patient presentations and journal clubs illustrate how molecular biology affects the practice of medicine.

INDE 216: Cells to Tissues

Focuses on the cell biology and structural organization of human tissues as self-renewing systems. Topics include identification and differentiation of stem cells, regulation of the cell cycle and apoptosis in normal and cancerous cells, cell adhesion and polarity in epithelial tissues, intracellular transport, and cell migration. Histology laboratory sessions examine normal and abnormal samples of blood, epithelia, connective tissue, muscle, bone and cartilage. Patient presentations and small group discussions of current medical literature illustrate how cell biology influences medical practice.

SURG 203: Clinical Anatomy

Introduction to human structure and function presented from a clinical perspective. Includes clinical scenarios, frequently used medical imaging techniques, and interventional procedures to illustrate the underlying anatomy. Students participate in lectures and engage in dissection of the human body in the anatomy laboratory. Surgery 203 presents structures of the head, neck, thorax, abdomen, pelvis, back, upper and lower limbs.

SURG 201: Embryology

This course focuses on the structural development of the human body from embryo to fetus to early post-natal life. Topics include formation of the cardiovascular, respiratory, musculoskeletal, gastrointestinal, reproductive, and renal systems, as well as common clinical conditions that arise from abnormalities of development.

EMED 201: Basic Cardiac Life Support (BLS)

All medical students must be certified in Basic Cardiac Life Support before the end of the first (autumn) quarter. Students who provide documentation of certification received within six months prior to the date of matriculation will be exempted from the requirement. The course teaches one- and two-rescuer CPR, management of an obstructed airway, and CPR for infants and children. Upon completion of the course, students receive an American Heart Association certificate in BLS.

BIOC 200: Applied Biochemistry

Fundamental concepts of biochemistry as applied to clinical medicine. Topics include thermodynamics, enzyme kinetics, vitamins and cofactors, metabolism of carbohydrates, lipids, amino acids and nucleotides, and the integration of metabolic pathways. Clinical case studies discussed in small-group, problem-based learning sessions.

GENE 202: Human Genetics

Utilizes lectures and small group discussions to develop a working knowledge of human genetics as applicable to clinical medicine and research. Basic principles of inheritance, risk assessment, and population genetics, illustrated by using clinical examples drawn from diverse areas of medical genetics practice including prenatal, pediatric, adult and cancer genetics. Practical aspects of molecular and cytogenetic diagnostic methods emphasized. Existing and emerging treatment strategies for single gene disorders also covered. Prerequisites: basic genetics.

INDE 218: Histology

This course focuses on the microscopic structure of the major organ systems, including the cardiovascular, respiratory, gastrointestinal, endocrine, renal, and reproductive systems. Sessions examine the unique features of the cells and tissues that comprise the major organs, describe how they contribute to the organs’ functions, and explore how they form the foundation for many pathologic processes.

INDE 263: Microbiology and Infectious Diseases I

First course in a two-course series exploring microbiology, pathogenesis, and clinical issues associated with infectious diseases. Simulated patient cases serve as a springboard discussion on viral, bacterial, fungal, protozoal and helminthic pathogens. Online videos and self-assessments followed by interactive sessions and problem sets.

NBIO 206: The Nervous System

Structure and function of the nervous system, including neuroanatomy, neurophysiology, and systems neurobiology. Topics include the properties of neurons and the mechanisms and organization underlying higher functions. Framework for general work in neurology, neuropathology, clinical medicine, and for more advanced work in neurobiology. Lecture and lab components must be taken together.

IMM 205: Immunology in Health and Disease

Concepts and application of adaptive and innate immunology and the role of the immune system in human diseases. Case presentations of diseases including autoimmune diseases, infectious disease and vaccination, hematopoietic and solid organ transplantation, genetic and acquired immunodeficiencies, hypersensitivity reactions, and allergic diseases. Problem sets based on lectures and current clinical literature. Laboratory in acute and chronic inflammation.

DBIO 201: Cells and Signaling in Regenerative Medicine

Conserved molecular and cellular pathways regulate tissue and organ homeostasis. Errors in these pathways result in human diseases. Manipulation of key cells and signals is leading to new strategies for stimulating tissue formation and regeneration. Topics include: stem cells, molecules regulating stem cell proliferation and differentiation, signaling pathways, gene regulation, embryonic stem cells, programmed cell death, cell lineage, tissue regeneration, use of stem cells in transplantation. Organoids. Emphasis on links between stem cells, signals, and clinically significant topics including diabetes, bone loss, cancer, and aging.

INDE 265: Microbiology and Infectious Diseases II

This second course in a two-course series explores microbiology, pathogenesis, andclinical issues associated with infectious diseases. Patient cases provide the springboard for discussions on microbiomes, diarrhea, hepatitis, STIs, helminths, zoonoses, and systemic diseases. Online videos and self-assessments are followed by interactive sessions and problem sets.

Additional Resources

Other Schedules

Class Time Schedules  (for electives & lunchtime seminars)

Course Resources

School of Medicine Academic Calendar

School of Medicine Course Catalog - School of Medicine-only Courses

Explore Courses - University-wide Courses

Axess - Course Enrollment

Canvas - Course Administration

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