iCAS - Imaging Collaterals in Acute Stroke
The overall goal of the imaging the Collaterals in Acute Stroke (iCAS) study is to identify and quantify cerebral blood flow (CBF) delivered via collateral routes using arterial spin labeling (ASL), a non-contrast MRI technique, and to determine its impact on ischemic lesion growth and patient outcome. NCT02225730
PI: Gregory Zaharchuk, MD
SHINE - Stroke Hyperglycemia Insulin Network Effort Trial
This is a Phase III multicenter, randomized and controlled clinical trial of 1400 patients within 12 hours of stroke symptom onset, with diabetes and glucose concentrations of over 110 mg/dL on initial evaluation to determine if treatment of hyperglycemic acute ischemic stroke patients with targeted glucose concentration (80mg/dL - 130 mg/dL) will be safe and result in improved 3 month outcome after stroke. Protocol ID: 23077, NCT01369069
PI: James Quinn, MD
Blood Transcriptome of Transient Ischemic Attack
This study will examine gene expression in the blood of patients with Transient Ischemic Attach (TIA) / minor strokes compared to various types of control subjects. The purpose of this study is to learn whether there are changes in molecules in blood called RNA change after TIA / minor stroke.
Protocol ID: 37711
PI: Paul George, MD, PhD
SALVO - Statins Augment Small Vessel Function and Improve Outcomes in Acute Ischemic Stroke
The purpose of this research study is to learn whether people who are taking a type of drug, called statins have different outcomes after they have a stroke than people who do not take statins. Statins are a type of medicine used to lower cholesterol and prevent heart disease or stroke.
Protocol ID: 39700
PI: Christina Mijalski-Cells, MD