Courses - Research Training in Pediatric Nonmalignant Hematology and Stem Cell Biology


Pathology 290

Pediatric Nonmalignant Hematology and Stem Cell Biology

This course covers a broad range of topics in both basic and translational aspects of nonmalignant hematology and stem cell biology. Pediatric hematologic disorders provide an important paradigm to study other developmental systems. Subjects covered include hematopoiesis, basic stem cell biology, endothelial cell development, alternative models to study nonmalignant hematology and stem cell biology (zebrafish and drosophila), defects in white cell function, basic research in stem cell transplantation, state of the art methods in nonmalignant hematology and stem cell biology (genomics, proteomics, and gene therapy), and bioinformatics.

There will be two lectures each week for the winter quarter. Twenty different faculty members who are experts in their field will give lectures. There is a final take-home exam that will be graded.


  • January 6 to March 12, 2015
  • Tuesday and Thursdays from 4-5pm
  • Lorry Lokey Stem Cell Research Building, Room G1000
  • *except for March 5, 2015 at Li Ka Shing Center Room 209




Tuesday, January 6, 2015

Kathleen Sakamoto, MD, PhD

Introduction to the course and hematopoiesis

Thursday, January 8, 2015

Judith Shizuru, MD, PhD

Biology of stem cell transplantation

Tuesday, January 13, 2015

Helen Blau, PhD

Basic research on stem cell biology

Thursday, January 15, 2015

Christopher Contag, PhD

Imaging and models to study hematology

Tuesday, January 20, 2015

Dean Felsher, MD, PhD

Mouse models of hematologic diseases

Thursday, January 22, 2015

Anupama Narla, MD

Bone marrow failure and ribosome defects

Tuesday, January 27, 2015

Marcus Breese, PhD

Bioinformatics and research

Thursday, January 29, 2015

Kara Davis, DO


Tuesday, February 3, 2015

Michael Jeng, MD

Nonmalignant hematology: histiocytosis

Thursday, February 5, 2015

Stanley Schrier, MD

Clinical overview of disease of red blood cells

Tuesday, February 10, 2015

Steven Artandi, MD, PhD

Dyskeratosis congenita and telomeres

Thursday, February 12, 2015



Tuesday, February 17, 2015

Mark Kay, MD, PhD

Gene therapy

Thursday, February 19, 2015

James Chen, PhD

Zebrafish as models of hematology and stem cells

Tuesday, February 24, 2015

Calvin Kuo, MD, PhD

Endothelial cell development

Thursday, February 26, 2015

Maria Grazia Roncarolo, MD

Cellular therapies for stem cell transplantation

Tuesday, March 3, 2015

Kenneth Weinberg, MD

Stem cell engraftment and immune reconstitution

Thursday, March 5, 2015


Erinn Rankin, PhD

Bone marrow microenvironment

Tuesday, March 10, 2015

Matthew Porteus, MD, PhD

Gene therapy and engineered nucleases

Thursday, March 12, 2015

Joseph Lipsick, MD, PhD; Kathleen Sakamoto, MD, PhD

Drosophila and models to study hematology and stem cells; Final Exam handed out