Resources for Stanford clinical and translational researchers.
Spectrum awards pilot grants to 32 projects
Thirty-two teams from Stanford have received a total of $1,125,733 in research funding through the Spectrum pilot grant program. Seven of these projects were co-funded by Stanford Health Care and the Office of the Dean, as part of the new Stanford Health Care Innovation Challenge. Grants were awarded in five areas: medical technologies, therapeutics, population health, community engagement, and predictives and diagnostic medicine. A list of projects and awardees is posted here.
Call for proposals:
Spectrum KL2/TL1 training awards

Applications for the Spectrum KL2 and TL1 clinical-research mentored career development training awards are due on March 1, 2015. Both programs provide promising scholars with financial support, training and mentoring to help them initiate research that accelerates the translation of medical discoveries into better health. Junior faculty and senior fellows are encouraged to apply
Biodesign textbook and video library available
The second edition of “Biodesign: The Process of Innovating Medical Technologies” is now available, along with a library of nearly 300 videos, publicly accessible, that reinforce key concepts in the biodesign innovation process, from need finding to regulatory approval.


Stanford team designs process for reducing stroke disability and costs
A new stroke care delivery model, developed by researchers at the Stanford Clinical Excellence Research Center (CERC) and partially funded by Spectrum, offers evidence-based strategies that enable clinics and hospitals to improve stroke patient outcomes while at the same time lowering costs related to their care. These combined strategies for prevention, acute treatment and post-stroke care could lower U.S. health-care costs by as much as $1.6 billion per year.
Retinal-scan analysis can predict advance of macular degeneration
A Spectrum-funded team has found a new way to forecast which patients with age-related macular degeneration are likely to suffer from the most debilitating form of the disease. Simply by analyzing imaging data that is already commonly collected in eye doctors’ offices, ophthalmologists could make smarter decisions about when to schedule an individual patient’s next office visit, in order to optimize the chances of detecting progression before it causes blindness.
Biodesign device alleviates dry eye 
A search for medical needs in eye clinics led Stanford Biodesign fellows to develop an implantable neurostimulator that painlessly increases natural tear production for this painful condition that affects more than 20 million Americans. It is now in clinical trials. Early support for this project came from Biodesign and Spectrum.
Human Immune Monitoring Center featured in chronic fatigue study article
The Stanford Initiative on Infection-Associated Chronic Diseases is a research project using cutting-edge technologies to identify the biomarkers and root causes of chronic fatigue syndrome. Working at the Human Immune Monitoring Center, a Spectrum-supported resource, team members are searching 600 blood samples for infectious microbes, inflammation-related molecules and genetic flaws. This study was featured in a Stanford Medicine magazine cover story.


Spectrum director named chair-elect of AAAS medical sciences
Harry Greenberg, professor of medicine and of microbiology and immunology, was voted chair-elect of the American Association of the Advancement of Science Section on Medical Sciences. He directs Spectrum and is the medical school’s senior associate dean for research. Dr. Greenberg was recently interviewed by Medical College of Wisconsin on the role of the CTSA-supported institutions in accelerating better health here.
Webb promoted to assistant dean
Chris Webb, PhD, Spectrum’
s executive director, was promoted to assistant dean of clinical and translational research at the school of medicine. Webb’s management of the most recent $50 million proposal for a new Clinical and Translational Science Award from the National Institutes of Health resulted in a perfect score for Stanford — giving the proposal top ranking among the 30 applications from leading universities and other academic medical centers across the country.

Altman to lead Spectrum diagnostics accelerator
Russ Altman, MD, PhD, professor of bioengineering, of genetics and of biomedical informatics research, will replace Atul Butte, MD, PhD, as the faculty director of SPADA, the Stanford Predictives and Diagnostics Accelerator. SPADA assists interdisciplinary innovators in research, development and deployment of technologies that improve human health through disease prediction and/or diagnosis.


Stanford cancer trials mobile app available
The Stanford Cancer Institute (SCI) has just released a Stanford cancer clinical trials search tool that runs on mobile devices. This "SCI Trials” app is available as a free download from the iTunes and Google Play websites.
New Stanford Population Health Sciences website launched
Visit this website for news on training, events and funding opportunities for members of Stanford’s Population Health Sciences community. You can also follow and share population science news on the group's new Twitter account, @StanPopHealth.

Guidance on reporting the data and results of clinical trials

In a recent JAMA viewpoint, NIH leaders Kathy Hudson, PhD, and Francis Collins, MD, PhD, discuss the proposed rule to require public sharing of summary data from certain clinical trials of FDA-regulated drugs and devices. In addition, the Institute of Medicine just published a major report on sharing clinical trial data. Steven Goodman, MD, MHS, PhD, who was on the report committee, discusses issues to consider in an editorial in Annals of Internal Medicine.

Request for info on NLM guidelines for sharing study data
The National Library of Medicine has posted an RFI for public input on principles and policies that govern the sharing of data from clinical trials, addressing areas such as biomedical informatics and electronic health records. Steven Goodman, MD, MHS, PhD, and Russ Altman, MD, PhD, who have been appointed to an advisory committee to the NIH director on these policies, strongly encourage Stanford faculty to provide input. Feedback will be accepted through March 13, 2015.


SEPI: Expert Tips for Expediting Clinical Trial Contracts and Budgets
Feb. 25, 12:00 – 1:00pm, Alway Bldg, Rm M114 or streaming
In this session, a Clinical Trial Research Process Manager (budgeting expert) and a Clinical Trials Contract Officer will review the major steps in getting a study budget and contract completed. 

SEPI: Study Participant Recruitment Tools and Strategies
Mar. 25, 12:00 – 1:00pm, Li Ka Shing Center, Rm LK130 
Population Health Sciences’ Distinguished Lecture Series
"Individualized and Population Health: Two Sides of the Same Coin"

Mar. 27, 12:30 – 1:45pm, Li Ka Shing Center, Rm LK120
Scott Zeger, professor of biostatistics from Johns Hopkins University, will address some of the major quantitative approaches to using population data to improve health care decisions about the individual.

Intensive Course in Clinical Research (ICCR): Study design and performance
Sept. 14-18, 2014, Stanford campus
Join the Spectrum team for five packed days of professional development in research study design. This intensive immersion experience in clinical research is intended for new investigators at the junior faculty, resident or fellow level. To learn more, visit this webpage.

CME Online: Statistics for Medical Professionals
This self-paced, online course provides medical professionals with a foundational understanding of probability and statistics, and shows participants how to analyze and avoid common statistical pitfalls with research data. It is taught by award-winning instructor Kristin Sainani, PhD, a clinical assistant professor of health research and policy.
Workshops, seminars, and training
The Spectrum education calendar lists many educational activities related to clinical and translational medicine held each month.
Don’t forget to cite the grant
Projects that are supported by Spectrum’s Clinical and Translational Science Award (CTSA) — through funding, consulting, CTRU use or other services — are required to use this acknowledgement wording for publications, news releases, websites and other communications:
“This work was supported by the Stanford Clinical and Translational Science Award (CTSA) to Spectrum (UL1 TR001085). The CTSA program is led by the National Center for Advancing Translational Sciences (NCATS) at the National Institutes of Health (NIH). The content is solely the responsibility of the authors and does not necessarily represent the official views of the NIH.”
Questions about clinical and translational research at Stanford?
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Image credits: mariusFM77/iStock (lightbulb); Kris Newby (scholars photo); Cambridge University Press (Biodesign cover); Steve Fisch (CT scanner); Wikipedia (retinal photo); Oculeve (dry-eye implant); Timothy Archibald (Mark Davis photo).

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