Muthukumar Ramanathan

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Muthukumar Ramanathan

My past research interest has been on understanding cytoskeletal dynamics and in particular the role of downstream effectors of small GTPases such as MRCK. MRCK has been shown to phosphorylate and activate myosin II with the aid of an adaptor protein and consequently cause actomyosin retrograde flow which results in cell movement. Working on an isoform of the adaptor protein LRAP35b, showed that LRAP35b complexs with MRCK and is involved in Mesencyhmal-Epithelial Transition.