Gene Ontology Consortium

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Gene Ontology: the framework for the model of biology. The GO defines concepts/classes used to describe gene function, and relationships between these concepts. It classifies functions along three aspects:

molecular function
molecular activities of gene products
cellular component
where gene products are active
biological process
pathways and larger processes made up of the activities of multiple gene products.



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GO annotations: the model of biology. Annotations are statements describing the functions of specific genes, using concepts in the Gene Ontology. The simplest and most common annotation links one gene to one function, e.g. FZD4 + Wnt signaling pathway. Each statement is based on a specified piece of evidence. more

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