Department of Embryology | Understanding Fundamental Developmental Mechanisms at The Cellular and Molecular Level

Sisterly sacrifice among ovarian germ cells key to egg development

Baltimore, MD—New work from Carnegie’s Allan Spradling and Lei Lei demonstrates that mammalian egg cells gain crucial cellular components at an early stage from their undifferentiated sister cells, called germ cells. This mechanism had previously only been documented in...

Matt Sieber Honored with First Carnegie “Postdoctoral Innovation and Excellence” Award

Washington, D.C.—Matthew Sieber, a postdoctoral fellow at the Department of Embryology, has been honored for his extraordinary accomplishments, through a new program that recognizes exceptional Carnegie postdoctoral scholars who have demonstrated both scientific...

To burn sugar or not to burn sugar: How eggs store fuel for embryo development

Baltimore, MD— Reproduction is highly dependent on diet and the ability to use nutrients to grow and generate energy. This is clearly seen in women, who must provide all the nutritional building blocks required to support a growing embryo. As a result, metabolic diseases...

‘Ghost Fibers’ Left Behind by Injured Muscle Cells Guide Stem Cells Into Position for Regeneration

San Diego, CA— Ghosts are not your typical cell biology research subjects. But scientists at the Carnegie Institution for Science and the National Institute of Child Health and Human Development (NICHD) who developed a technique to observe muscle stem/progenitor cells...

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