NIH Director's Transformative Research Award

Funding opportunities for exceptionally innovative and unconventional research projects

NIH Director's Transformative Research Award

Part of the High-Risk, High-Reward Research program, the award supports individuals or teams proposing transformative projects that are inherently risky and untested but have the potential to create or overturn fundamental paradigms and may require very large budgets.

  • Open to all career stages
  • Open to individuals or teams
  • No preliminary data required
  • Flexible budgets
  • Effort commensurate to project needs



Application Information

Funding Opportunities
FY 2020

Closed September 20, 2019

               NIH Director's Transformative Research Award FAQs

Q&A Webinar Video

Watch the live webinar held on July 24, 2019, featuring short presentations from NIH program and review staff and answering submitted questions from the public.

Download the July 24, 2019 Q&A webinar material

Transformative Research Award Informational Video (April 2019)

Learn more about the eligibility requirements, award cycle, application process, review process, and award requirements for the NIH Director's Transformative Research Award in this short 2-minute video.

Join our Listserv or contact us at

This page last reviewed on January 8, 2020