School of Medicine
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Helen M. Blau
The Donald E. and Delia B. Baxter Foundation Professor and Director, Baxter Laboratory for Stem Cell Biology
Current Research and Scholarly Interests Prof. Helen Blau's research area is regenerative medicine with a focus on stem cells. Her research on nuclear reprogramming and demonstrating the plasticity of cell fate using cell fusion is well known and her laboratory has also pioneered the design of biomaterials to mimic the in vivo microenvironment and direct stem cell fate. Current findings are leading to more efficient iPS generation, cell based therapies by dedifferentiation a la newts, and discovery of novel molecules and therapies.
Chia Yu Alex Chang
Instructor, Microbiology & Immunology - Baxter Laboratory
Current Research and Scholarly Interests Duchenne muscular dystrophy (DMD) is an X-chromosome-linked genetic disease that is caused by a mutation in the dystrophin gene and affects 1 in every 3500 boys. DMD patients suffer progressive muscle wasting and eventual cardiorespiratory failure that results in an early death in the second or third decade of life. Although extensive research effort has been invested, lack of a good mouse model that mimics the cardiac failure hinders research. We have developed a novel mouse model that exhibit all the symptoms found in DMD patients and our research is aimed at understanding the cardiac failure in DMD for future therapeutic interventions. Our mouse model fully recapitulates the DMD symptoms because we also took into account of the size of human protection DNA on chromosomal ends (telomere) compared to mouse. We would like to study the cause of cardiac failure in our mouse model by 1) determine if telomere shortening is specific to cardiomyocytes, 2) evaluate the level of cellular damage caused by oxidative stress and 3) identify the source of oxidative stress. These experiments will help us to better understand cardiac failure in DMD patients and allow testing of therapeutic interventions.
Peter K. Jackson
Professor of Microbiology and Immunology (Baxter Labs)
Current Research and Scholarly Interests Cell cycle and cyclin control of DNA replication .
Life Science Research Professional 2, Microbiology and Immunology - Baxter Labs
Current Role at Stanford 1. Perform complex (lab and/or field) experiments for a major portion of the research project.
Maintain detailed records of experiments and outcomes
2. Interpret and analyze results, often where few guidelines exist. Based on prior results,
contribute to development of new research protocols and procedures or adaptation of existing
3. Make recommendations on plan design and/or research direction to principal investigator
4. Work with health and safety department to ensure lab complies with regulations and all
5. Participate in multidisciplinary teams across different faculties or schools
6. Oversee supply and equipment budget under supervision of principal investigator or business
7. Perform ongoing literature review to remain current with new procedures and related research;
present findings for lab work group
8. Contribute substantively to the preparation of papers for publication, especially in the results
9. May contribute to publication of findings and present ongoing work and findings to colleagues
at academic conferences
10. Supervise (either formally or informally) staff or students as needed, including oversight and
instruction on techniques, as well as consultation on project work. Serve as technical resource
for other research staff
11. Perform general lab maintenance as needed; maintain lab stock, manage chemical inventory
and safety records, and provide general lab support as needed. May assist with purchasing