Christopher Cambier
Postdoctoral Research Fellow, Chemistry
Professional Education
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Bachelor of Science, Calif Polytechnic State Univ, S.L.O. (2007)
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Doctor of Philosophy, University of Washington (2014)
All Publications
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Lysosomal Disorders Drive Susceptibility to Tuberculosis by Compromising Macrophage Migration
CELL
2016; 165 (1): 139-152
View details for DOI 10.1016/j.cell.2016.02.034
View details for Web of Science ID 000372785600016
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Host Evasion and Exploitation Schemes of Mycobacterium tuberculosis
CELL
2014; 159 (7): 1497-1509
Abstract
Tuberculosis, an ancient disease of mankind, remains one of the major infectious causes of human death. We examine newly discovered facets of tuberculosis pathogenesis and explore the evolution of its causative organism Mycobacterium tuberculosis from soil dweller to human pathogen. M. tuberculosis has coevolved with the human host to evade and exploit host macrophages and other immune cells in multiple ways. Though the host can often clear infection, the organism can cause transmissible disease in enough individuals to sustain itself. Tuberculosis is a near-perfect paradigm of a host-pathogen relationship, and that may be the challenge to the development of new therapies for its eradication.
View details for DOI 10.1016/j.cell.2014.11.024
View details for Web of Science ID 000347922500006
View details for PubMedID 25525872