About
Dr. Stephen Quake's interests lie at the nexus of physics, biology, and biotechnology. His research is concerned with developing new approaches to biological measurement and applying these approaches to problems of both fundamental and medical interest. Areas of interest include genomic diagnostics, systems biology, microbial ecology, and single cell genomics.
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Featured publication
This report published in Cell Reports in July 2016 reveals the diversity of striatal cells using single-cell RNA sequencing. It presents the continuous expression gradients within neuronal subtypes and astrocytes that may be fundamental to transcriptional diversity within these cells. These findings open up the possibility that functional diversity within a compelx tissue arises from a small number of discrete cell types, which can exist in a continuous spectrum of functional states.
QnAs with Stephen Quake
The National Academy of Sciences bestowed the 2016 Raymond and Beverly Sackler Prize in Convergence Research on Dr. Stephen Quake. PNAS spoke to Dr. Quake to mark the occasion.
“It’s been rewarding to see how one can apply simple ideas about measurement from physics to a range of biological problems,” said Dr. Quake.
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