Publications

• HLA-DPB1 and HLA Class I Confer Risk of and Protection from Narcolepsy
  Ollila, H. M., Ravel, J.-M., Han, F., Faraco, J., Lin, L., & Mignot, E. (2015). HLA-DPB1 and HLA Class I Confer Risk of and Protection from Narcolepsy. AMERICAN JOURNAL OF HUMAN GENETICS, 96(1), 136-146.
• Design and Validation of a Periodic Leg Movement Detector
  Moore, H., Leary, E., Lee, S.-Y., Carrillo, O., Stubbs, R., & Mignot, E. (2014). Design and Validation of a Periodic Leg Movement Detector. PLOS ONE, 9(12).
• Narcolepsy and Predictors of Positive MSLTs in the Wisconsin Sleep Cohort
  Goldbart, A., Peppard, P., Finn, L., Ruoff, C. M., Barnet, J., & Mignot, E. (2014). Narcolepsy and Predictors of Positive MSLTs in the Wisconsin Sleep Cohort. SLEEP, 37(6), 1043-1051.
• Sleep-spindle detection: crowdsourcing and evaluating performance of experts, non-experts and automated methods Warby, S. C., Wendt, S. L., Welinder, P., Munk, E. Gs., Carrillo, O., & Mignot, E. (2014). Sleep-spindle detection: crowdsourcing and evaluating performance of experts, non-experts and automated methods. NATURE METHODS, 11(4), 385-?.
  
• Genome wide analysis of narcolepsy in China implicates novel immune loci and reveals changes in association prior to versus after the 2009 H1N1 influenza pandemic. Han, F., Faraco, J., Dong, X. S., Ollila, H. M., Lin, L., & Mignot, E. (2013). Genome wide analysis of narcolepsy in China implicates novel immune loci and reveals changes in association prior to versus after the 2009 H1N1 influenza pandemic. PLoS genetics, 9(10).
  
• Nocturnal rapid eye movement sleep latency for identifying patients with narcolepsy/hypocretin deficiency. Andlauer, O., Moore, H., Jouhier, L., Drake, C., Peppard, P. E., & Mignot, E. (2013). Nocturnal rapid eye movement sleep latency for identifying patients with narcolepsy/hypocretin deficiency. JAMA neurology, 70(7), 891-902.
  
• Decreased incidence of childhood narcolepsy 2 years after the 2009 H1N1 winter flu pandemic Han, F., Lin, L., Li, J., Dong, X. S., & Mignot, E. (2013). Decreased incidence of childhood narcolepsy 2 years after the 2009 H1N1 winter flu pandemic. ANNALS OF NEUROLOGY, 73(4), 560-560.
  
• ImmunoChip Study Implicates Antigen Presentation to T Cells in Narcolepsy Faraco, J., Lin, L., Kornum, B. R., Kenny, E. E., Trynka, G., & Mignot, E. (2013). ImmunoChip Study Implicates Antigen Presentation to T Cells in Narcolepsy. PLOS GENETICS, 9(2).
  
• ImmunoChip study implicates antigen presentation to T cells in narcolepsy. Faraco, J., Lin, L., Kornum, B. R., Kenny, E. E., Trynka, G., & Mignot, E. (2013). ImmunoChip study implicates antigen presentation to T cells in narcolepsy. PLoS genetics, 9(2).
  
• HLA-DQ association and allele competition in Chinese narcolepsy Han, F., Lin, L., Li, J., Dong, S. X., An, P., & Mignot, E. (2012). HLA-DQ association and allele competition in Chinese narcolepsy. TISSUE ANTIGENS, 80(4), 328-335.
  
• Predictors of Hypocretin (Orexin) Deficiency in Narcolepsy Without Cataplexy Andlauer, O., Moore, H., Hong, S.-C., Dauvilliers, Y., Kanbayashi, T., & Mignot, E. (2012). Predictors of Hypocretin (Orexin) Deficiency in Narcolepsy Without Cataplexy. SLEEP, 35(9), 1247-1255.
  
• Mutations in DNMT1 cause autosomal dominant cerebellar ataxia, deafness and narcolepsy Winkelmann, J., Lin, L., Schormair, B., Kornum, B. R., Faraco, J., & Mignot, E. (2012). Mutations in DNMT1 cause autosomal dominant cerebellar ataxia, deafness and narcolepsy. HUMAN MOLECULAR GENETICS, 21(10), 2205-2210.
  
• ALLIANCE SLEEP QUESTIONNAIRE (ASQ) FEASIBILITY PILOT STUDY Leary, E. B., GRIFFIN, K. S., Malunjkar, S., Qadri, S., Ruoff, C. M., & Mignot, E. (2012). ALLIANCE SLEEP QUESTIONNAIRE (ASQ) FEASIBILITY PILOT STUDY. SLEEP, 35, A432-A433.
  
• ALLIANCE SLEEP QUESTIONNAIRE (ASQ): A COLLABORATIVE ONLINE SLEEP ASSESSMENT QUESTIONNAIRE Leary, E. B., Barger, L., Hall-Porter, J. M., Maislin, G., Peppard, P. E., & Mignot, E. (2012). ALLIANCE SLEEP QUESTIONNAIRE (ASQ): A COLLABORATIVE ONLINE SLEEP ASSESSMENT QUESTIONNAIRE. SLEEP, 35, A432-A432.
  
• Narcolepsy Onset Is Seasonal and Increased following the 2009 H1N1 Pandemic in China Han, F., Lin, L., Warby, S. C., Faraco, J., Li, J., & Mignot, E. (2011). Narcolepsy Onset Is Seasonal and Increased following the 2009 H1N1 Pandemic in China. ANNALS OF NEUROLOGY, 70(3), 410-417.
  
• Genetics of Sleep and Sleep Disorders Sehgal, A., & Mignot, E. (2011). Genetics of Sleep and Sleep Disorders. CELL, 146(2), 194-207.
  
• Common variants in P2RY11 are associated with narcolepsy Kornum, B. R., Kawashima, M., Faraco, J., Lin, L., Rico, T. J., & Mignot, E. (2011). Common variants in P2RY11 are associated with narcolepsy. NATURE GENETICS, 43(1), 66-U90.
  
• Narcolepsy is strongly associated with the T-cell receptor alpha locus Hallmayer, J., Faraco, J., Lin, L., Hesselson, S., Winkelmann, J., & Mignot, E. (2009). Narcolepsy is strongly associated with the T-cell receptor alpha locus. NATURE GENETICS, 41(6), 708-711.
  
• IGFBP3 Colocalizes with and Regulates Hypocretin (Orexin) Honda, M., Eriksson, K. S., Zhang, S., Tanaka, S., Lin, L., & Mignot, E. (2009). IGFBP3 Colocalizes with and Regulates Hypocretin (Orexin). PLOS ONE, 4(1).
  
• Cataplexy features in childhood narcolepsy Serra, L., Montagna, P., Mignot, E., Lugaresi, E., & Plazzi, G. (2008). Cataplexy features in childhood narcolepsy. MOVEMENT DISORDERS, 23(6), 858-865.
  
• Why we sleep: The temporal organization of recovery Mignot, E. (2008). Why we sleep: The temporal organization of recovery. PLOS BIOLOGY, 6(4), 661-669.
  
• Kleine-Levin syndrome: A systematic study of 108 patients Arnulf, I., Lin, L., Gadoth, N., File, J., Lecendreux, M., & Mignot, E. (2008). Kleine-Levin syndrome: A systematic study of 108 patients. ANNALS OF NEUROLOGY, 63(4), 482-493.
  
• Correlates of sleep-onset REM periods during the Multiple Sleep Latency Test in community adults Mignot, E., Lin, g L., Finn, L., Lopes, C., Pluff, K., & Young, T. (2006). Correlates of sleep-onset REM periods during the Multiple Sleep Latency Test in community adults. BRAIN, 129, 1609-1623.
  
• Short sleep duration is associated with reduced leptin, elevated ghrelin, and increased body mass index Taheri, S., Lin, L., Austin, D., Young, T., & Mignot, E. (2004). Short sleep duration is associated with reduced leptin, elevated ghrelin, and increased body mass index. PLOS MEDICINE, 1(3), 210-217.
  
• The role of cerebrospinal fluid hypocretin measurement in the diagnosis of narcolepsy and other hypersomnias Mignot, E., Lammers, G. J., Ripley, B., Okun, M., Nevsimalova, S., & Nishino, S. (2002). The role of cerebrospinal fluid hypocretin measurement in the diagnosis of narcolepsy and other hypersomnias. ARCHIVES OF NEUROLOGY, 59(10), 1553-1562.
  
• Complex HLA-DR and -DQ interactions confer risk of narcolepsy-cataplexy in three ethnic groups Mignot, E., Lin, L., Rogers, W., Honda, Y., Qiu, X. H., & Risch, N. (2001). Complex HLA-DR and -DQ interactions confer risk of narcolepsy-cataplexy in three ethnic groups. AMERICAN JOURNAL OF HUMAN GENETICS, 68(3), 686-699.
  
• A mutation in a case of early onset narcolepsy and a generalized absence of hypocretin peptides in human narcoleptic brains Peyron, C., Faraco, J., Rogers, W., Ripley, B., Overeem, S., & Mignot, E. (2000). A mutation in a case of early onset narcolepsy and a generalized absence of hypocretin peptides in human narcoleptic brains. NATURE MEDICINE, 6(9), 991-997.
  
• The sleep disorder canine narcolepsy is caused by a mutation in the hypocretin (orexin) receptor 2 gene Lin, L., Faraco, J., Li, R., KADOTANI, H., Rogers, W., & Mignot, E. (1999). The sleep disorder canine narcolepsy is caused by a mutation in the hypocretin (orexin) receptor 2 gene. CELL, 98(3), 365-376.
  
• Validation of a cataplexy questionnaire in 983 sleep-disorders patients Anic-Labat, S., Guilleminault, C., Kraemer, H. C., Meehan, J., Arrigoni, J., & Mignot, E. (1999). Validation of a cataplexy questionnaire in 983 sleep-disorders patients. SLEEP, 22(1), 77-87.
  
• Pharmacological aspects of human and canine narcolepsy Nishino, S., & Mignot, E. (1997). Pharmacological aspects of human and canine narcolepsy. PROGRESS IN NEUROBIOLOGY, 52(1), 27-78.
  
• CANINE CATAPLEXY IS PREFERENTIALLY CONTROLLED BY ADRENERGIC-MECHANISMS - EVIDENCE USING MONOAMINE SELECTIVE UPTAKE INHIBITORS AND RELEASE ENHANCERS Mignot, E., RENAUD, A., Nishino, S., Arrigoni, J., Guilleminault, C., & Dement, W. C. (1993). CANINE CATAPLEXY IS PREFERENTIALLY CONTROLLED BY ADRENERGIC-MECHANISMS - EVIDENCE USING MONOAMINE SELECTIVE UPTAKE INHIBITORS AND RELEASE ENHANCERS. PSYCHOPHARMACOLOGY, 113(1), 76-82.
  
• HETEROZYGOSITY AT THE CANARC-1 LOCUS CAN CONFER SUSCEPTIBILITY FOR NARCOLEPSY - INDUCTION OF CATAPLEXY IN HETEROZYGOUS ASYMPTOMATIC DOGS AFTER ADMINISTRATION OF A COMBINATION OF DRUGS ACTING ON MONOAMINERGIC AND CHOLINERGIC SYSTEMS Mignot, E., Nishino, S., Sharp, L. H., Arrigoni, J., Siegel, J. M., & Dement, W. C. (1993). HETEROZYGOSITY AT THE CANARC-1 LOCUS CAN CONFER SUSCEPTIBILITY FOR NARCOLEPSY - INDUCTION OF CATAPLEXY IN HETEROZYGOUS ASYMPTOMATIC DOGS AFTER ADMINISTRATION OF A COMBINATION OF DRUGS ACTING ON MONOAMINERGIC AND CHOLINERGIC SYSTEMS. JOURNAL OF NEUROSCIENCE, 13(3), 1057-1064.
  
• Inter-expert and intra-expert reliability in sleep spindle scoring. Wendt, S. L., Welinder, P., Sorensen, H. Bd., Peppard, P. E., Jennum, P., & Warby, S. C. (2015). Inter-expert and intra-expert reliability in sleep spindle scoring. Clinical neurophysiology , 126(8), 1548-1556.
  
• Sleep spindle alterations in patients with Parkinson's disease Christensen, J. Ae., Nikolic, M., Warby, S. C., Koch, H., Zoetmulder, M., & Jennum, P. J. (2015). Sleep spindle alterations in patients with Parkinson's disease. FRONTIERS IN HUMAN NEUROSCIENCE, 9.
  
• HLA-DQ Allele Competition in Narcolepsy: A Comment on Tafti et al. DQB1 locus alone explains most of the risk and protection in narcolepsy with cataplexy in Europe Ollila, H. M., Fernandez-Vina, M., & Mignot, E. (2015). HLA-DQ Allele Competition in Narcolepsy: A Comment on Tafti et al. DQB1 locus alone explains most of the risk and protection in narcolepsy with cataplexy in Europe. SLEEP, 38(1), 147-151.
  
• HLA DQB1*06:02 Negative Narcolepsy with Hypocretin/Orexin Deficiency Han, F., Lin, L., Schormair, B., Pizza, F., Plazzi, G., & Mignot, E. (2014). HLA DQB1*06:02 Negative Narcolepsy with Hypocretin/Orexin Deficiency. SLEEP, 37(10), 1601-1608.
  
• Risk of Narcolepsy Associated with Inactivated Adjuvanted (AS03) A/H1N1 (2009) Pandemic Influenza Vaccine in Quebec Montplaisir, J., Petit, D., Quinn, M.-J., Ouakki, M., Deceuninck, G., & De Wals, P. (2014). Risk of Narcolepsy Associated with Inactivated Adjuvanted (AS03) A/H1N1 (2009) Pandemic Influenza Vaccine in Quebec. PLOS ONE, 9(9).
  
• Retraction of the Research Article: "CD4+ T cell autoimmunity to hypocretin/orexin and cross-reactivity to a 2009 H1N1 influenza A epitope in narcolepsy". De la Herrán-Arita, A. K., Kornum, B. R., Mahlios, J., Jiang, W., Lin, L., & Mignot, E. (2014). Retraction of the Research Article: "CD4+ T cell autoimmunity to hypocretin/orexin and cross-reactivity to a 2009 H1N1 influenza A epitope in narcolepsy". Science translational medicine, 6(247), 247rt1-?.
  
• History of narcolepsy at Stanford University Mignot, E. Jm. (2014). History of narcolepsy at Stanford University. IMMUNOLOGIC RESEARCH, 58(2-3), 315-339.
  
• The structured Diagnostic Interview for Sleep Patterns and Disorders: rationale and initial evaluation Merikangas, K. R., Zhang, J., Emsellem, H., Swanson, S. A., Vgontzas, A., & Mignot, E. (2014). The structured Diagnostic Interview for Sleep Patterns and Disorders: rationale and initial evaluation. SLEEP MEDICINE, 15(5), 530-535.
  
• Periodic Leg Movements during Sleep Are Associated with Polymorphisms in BTBD9, TOX3/BC034767, MEIS1, MAP2K5/SKOR1, and PTPRD. Moore, H., Winkelmann, J., Lin, L., Finn, L., Peppard, P., & Mignot, E. (2014). Periodic Leg Movements during Sleep Are Associated with Polymorphisms in BTBD9, TOX3/BC034767, MEIS1, MAP2K5/SKOR1, and PTPRD. Sleep, 37(9).
  
• Dual Cases of Type 1 Narcolepsy with Schizophrenia and Other Psychotic Disorders Canellas, F., Lin, L., Rosa Julia, M., Clemente, A., Vives-Bauza, C., & Mignot, E. (2014). Dual Cases of Type 1 Narcolepsy with Schizophrenia and Other Psychotic Disorders. JOURNAL OF CLINICAL SLEEP MEDICINE, 10(9), 1011-1018.
  
• CD4(+) T Cell Autoimmunity to Hypocretin/Orexin and Cross-Reactivity to a 2009 H1N1 Influenza A Epitope in Narcolepsy De la Herran-Arita, A. K., Kornum, B. R., Mahlios, J., Jiang, W., Lin, L., & Mignot, E. (2013). CD4(+) T Cell Autoimmunity to Hypocretin/Orexin and Cross-Reactivity to a 2009 H1N1 Influenza A Epitope in Narcolepsy. SCIENCE TRANSLATIONAL MEDICINE, 5(216).
  
• Increase of Histaminergic Tuberomammillary Neurons in Narcolepsy Valko, P. O., Gavrilov, Y. V., Yamamoto, M., Reddy, H., Haybaeck, J., & Scammell, T. E. (2013). Increase of Histaminergic Tuberomammillary Neurons in Narcolepsy. ANNALS OF NEUROLOGY, 74(6), 794-804.
  
• The autoimmune basis of narcolepsy Mahlios, J., De la Herran-Arita, A. K., & Mignot, E. (2013). The autoimmune basis of narcolepsy. CURRENT OPINION IN NEUROBIOLOGY, 23(5), 767-773.
  
• A Novel de novo Exon 21 DNMT1 Mutation Causes Cerebellar Ataxia, Deafness, and Narcolepsy in a Brazilian Patient Pedroso, J. L., Povoas Barsottini, O. G., Lin, L., Melberg, A., Oliveira, A. Sb., & Mignot, E. (2013). A Novel de novo Exon 21 DNMT1 Mutation Causes Cerebellar Ataxia, Deafness, and Narcolepsy in a Brazilian Patient. SLEEP, 36(8), 1257-1259.
  
• Hypocretin (orexin) neuropeptide precursor gene, HCRT, polymorphisms in early-onset narcolepsy with cataplexy Dong, X. S., Ma, S. F., Cao, C. W., Li, J., An, P., & Han, F. (2013). Hypocretin (orexin) neuropeptide precursor gene, HCRT, polymorphisms in early-onset narcolepsy with cataplexy. SLEEP MEDICINE, 14(6), 482-487.
  
• Genetic association, seasonal infections and autoimmune basis of narcolepsy Singh, A. K., Mahlios, J., & Mignot, E. (2013). Genetic association, seasonal infections and autoimmune basis of narcolepsy. JOURNAL OF AUTOIMMUNITY, 43, 26-31.
  
• Genome-wide association study of HLA-DQB1*06:02 negative essential hypersomnia Khor, S.-S., Miyagawa, T., Toyoda, H., Yamasaki, M., Kawamura, Y., & Tokunaga, K. (2013). Genome-wide association study of HLA-DQB1*06:02 negative essential hypersomnia. PEERJ, 1.
  
• Physiology. The perfect hypnotic? Mignot, E. (2013). Physiology. The perfect hypnotic?. Science , 340(6128), 36-38.
  
• High Prevalence of Precocious Puberty and Obesity in Childhood Narcolepsy with Cataplexy Poli, F., Pizza, F., Mignot, E., Ferri, R., Pagotto, U., & Plazzi, G. (2013). High Prevalence of Precocious Puberty and Obesity in Childhood Narcolepsy with Cataplexy. SLEEP, 36(2), 175-181.
  
• Daytime continuous polysomnography predicts MSLT results in hypersomnias of central origin Pizza, F., Moghadam, K. K., Vandi, S., Detto, S., Poli, F., & Plazzi, G. (2013). Daytime continuous polysomnography predicts MSLT results in hypersomnias of central origin. JOURNAL OF SLEEP RESEARCH, 22(1), 32-40.
  
• Genome-wide association study of HLA-DQB1*06:02 negative essential hypersomnia. Khor, S.-S., Miyagawa, T., Toyoda, H., Yamasaki, M., Kawamura, Y., & Tokunaga, K. (2013). Genome-wide association study of HLA-DQB1*06:02 negative essential hypersomnia. PeerJ, 1.
  
• Association of Sleep Disordered Breathing and Cognitive Deficit in APOE e4 Carriers. Nikodemova, M., Finn, L., Mignot, E., Salzieder, N., & Peppard, P. E. (2013). Association of Sleep Disordered Breathing and Cognitive Deficit in APOE e4 Carriers. Sleep, 36(6), 873-880.
  
• Narcolepsy with cataplexy mimicry: the strange case of two sisters. Pizza, F., Vandi, S., Poli, F., Moghadam, K. K., Franceschini, C., & Plazzi, G. (2013). Narcolepsy with cataplexy mimicry: the strange case of two sisters. Journal of clinical sleep medicine , 9(6), 611-612.
  
• Treatment of Sleep Disorders Pelayo, R., & Mignot, E. (2012). Treatment of Sleep Disorders. NEUROTHERAPEUTICS, 9(4), 685-686.
  
• Diagnosis, disease course, and management of patients with Kleine-Levin syndrome Arnulf, I., Rico, T. J., & Mignot, E. (2012). Diagnosis, disease course, and management of patients with Kleine-Levin syndrome. LANCET NEUROLOGY, 11(10), 918-928.
  
• A Practical Guide to the Therapy of Narcolepsy and Hypersomnia Syndromes Mignot, E. Jm. (2012). A Practical Guide to the Therapy of Narcolepsy and Hypersomnia Syndromes. NEUROTHERAPEUTICS, 9(4), 739-752.
  
• Clinical phenotype of patients with narcolepsy with cataplexy, cerebellar ataxia, deafness and neuropathy associated to DNMT1 gene mutation Moghadam, K. K., Pizza, F., Poli, F., Franceschini, C., Tonon, C., & Plazzi, G. (2012). Clinical phenotype of patients with narcolepsy with cataplexy, cerebellar ataxia, deafness and neuropathy associated to DNMT1 gene mutation. JOURNAL OF SLEEP RESEARCH, 21, 311-311.
  
• EARLY IVIg TREATMENT HAS NO EFFECT ON POST-H1N1 NARCOLEPSY PHENOTYPE OR HYPOCRETIN DEFICIENCY Knudsen, S., Biering-Sorensen, B., Kornum, B. R., Petersen, E. R., Ibsen, J. D., & Jennum, P. J. (2012). EARLY IVIg TREATMENT HAS NO EFFECT ON POST-H1N1 NARCOLEPSY PHENOTYPE OR HYPOCRETIN DEFICIENCY. NEUROLOGY, 79(1), 102-103.
  
• Time-course of cerebrospinal fluid histamine in the wake-consolidated squirrel monkey Zeitzer, J. M., Kodama, T., Buckmaster, C. L., Honda, Y., Lyons, D. M., & Mignot, E. (2012). Time-course of cerebrospinal fluid histamine in the wake-consolidated squirrel monkey. JOURNAL OF SLEEP RESEARCH, 21(2), 189-194.
  
• DQB1*06:02 allele-specific expression varies by allelic dosage, not narcolepsy status Lachmi, K. W., Lin, L., Kornum, B. R., Rico, T., Lo, B., & Mignot, E. (2012). DQB1*06:02 allele-specific expression varies by allelic dosage, not narcolepsy status. HUMAN IMMUNOLOGY, 73(4), 405-410.
  
• TCRA, P2RY11, and CPT1B/CHKB associations in Chinese narcolepsy Han, F., Lin, L., Li, J., Aran, A., Dong, S. X., & Mignot, E. (2012). TCRA, P2RY11, and CPT1B/CHKB associations in Chinese narcolepsy. SLEEP MEDICINE, 13(3), 269-272.
  
• CSF Levels of Hypocretin-1 (Orexin-A) Peak during Early Infancy in Humans Aran, A., Shors, I., Lin, L., Mignot, E., & Schimmel, M. S. (2012). CSF Levels of Hypocretin-1 (Orexin-A) Peak during Early Infancy in Humans. SLEEP, 35(2), 187-191.
  
• LEG MOVEMENT DETECTION SOFTWARE AND PERIODIC LEG MOVEMENT INDEX CALCULATOR MOORE, H. E., Warby, S., Woodward, S. H., Peppard, P. E., Young, T., & Mignot, E. (2012). LEG MOVEMENT DETECTION SOFTWARE AND PERIODIC LEG MOVEMENT INDEX CALCULATOR. SLEEP, 35, A264-A264.
  
• MUTATIONS IN DNMT1 CAUSE AUTOSOMAL DOMINANT CEREBELLAR ATAXIA, DEAFNESS AND NARCOLEPSY Winkelmann, J., Lin, L., Schormair, B., Kornum, B. R., Faraco, J., & Mignot, E. (2012). MUTATIONS IN DNMT1 CAUSE AUTOSOMAL DOMINANT CEREBELLAR ATAXIA, DEAFNESS AND NARCOLEPSY. SLEEP, 35, A11-A11.
  
• Complex movement disorders at disease onset in childhood narcolepsy with cataplexy. Plazzi, G., Pizza, F., Palaia, V., Franceschini, C., Poli, F., & Bhatia, K. P. (2011). Complex movement disorders at disease onset in childhood narcolepsy with cataplexy. Brain , 134, 3480-3492.
  
• Narcolepsy with hypocretin/orexin deficiency, infections and autoimmunity of the brain Kornum, B. R., Faraco, J., & Mignot, E. (2011). Narcolepsy with hypocretin/orexin deficiency, infections and autoimmunity of the brain. CURRENT OPINION IN NEUROBIOLOGY, 21(6), 897-903.
  
• Complex movement disorders at disease onset in childhood narcolepsy with cataplexy Plazzi, G., Pizza, F., Palaia, V., Franceschini, C., Poli, F., & Bhatia, K. P. (2011). Complex movement disorders at disease onset in childhood narcolepsy with cataplexy. BRAIN, 134, 3477-3489.
  
• Narcolepsy with Cataplexy Associated with Nocturnal Compulsive Behaviors: A Case-Control Study Palaia, V., Poli, F., Pizza, F., Antelmi, E., Franceschini, C., & Plazzi, G. (2011). Narcolepsy with Cataplexy Associated with Nocturnal Compulsive Behaviors: A Case-Control Study. SLEEP, 34(10), 1365-U100.
  
• Post-Streptococcal Antibodies Are Associated with Metabolic Syndrome in a Population-Based Cohort Aran, A., Lin, L., Finn, L. A., Weiner, K., Peppard, P., & Mignot, E. (2011). Post-Streptococcal Antibodies Are Associated with Metabolic Syndrome in a Population-Based Cohort. PLOS ONE, 6(9).
  
• Genome-Wide Association Study Identifies Novel Restless Legs Syndrome Susceptibility Loci on 2p14 and 16q12.1 Winkelmann, J., Czamara, D., Schormair, B., Knauf, F., Schulte, E. C., & Meitinger, T. (2011). Genome-Wide Association Study Identifies Novel Restless Legs Syndrome Susceptibility Loci on 2p14 and 16q12.1. PLOS GENETICS, 7(7).
  
• Presentations of Primary Hypersomnia in Chinese Children Han, F., Lin, L., Li, J., Aran, A., Dong, S. X., & Mignot, E. (2011). Presentations of Primary Hypersomnia in Chinese Children. SLEEP, 34(5), 627-632A.
  
• beta 2 adrenergic receptor polymorphisms and nocturnal blood pressure dipping status in the Wisconsin Sleep Cohort Study Vardeny, O., Peppard, P. E., Finn, L. A., Faraco, J. H., Mignot, E., & Hla, K. M. (2011). beta 2 adrenergic receptor polymorphisms and nocturnal blood pressure dipping status in the Wisconsin Sleep Cohort Study. JOURNAL OF THE AMERICAN SOCIETY OF HYPERTENSION, 5(2), 114-122.
  
• POST-STREPTOCOCCAL ANTIBODIES ARE ASSOCIATED WITH METABOLIC SYNDROME IN A POPULATION-BASED SAMPLE OF HEALTHY ADULTS Aran, A., Lin, L., Finn, L., Weiner, K., Peppard, P. E., & Mignot, E. (2011). POST-STREPTOCOCCAL ANTIBODIES ARE ASSOCIATED WITH METABOLIC SYNDROME IN A POPULATION-BASED SAMPLE OF HEALTHY ADULTS. SLEEP, 34, A222-A222.
  
• Transcriptional regulation of the hypocretin/orexin gene by NR6A1 Tanaka, S., Kodama, T., Nonaka, T., Toyoda, H., Arai, M., & Mignot, E. (2010). Transcriptional regulation of the hypocretin/orexin gene by NR6A1. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 403(2), 178-183.
  
• Clinical and Therapeutic Aspects of Childhood Narcolepsy-Cataplexy: A Retrospective Study of 51 Children Aran, A., Einen, M., Lin, L., Plazzi, G., Nishino, S., & Mignot, E. (2010). Clinical and Therapeutic Aspects of Childhood Narcolepsy-Cataplexy: A Retrospective Study of 51 Children. SLEEP, 33(11), 1457-1464.
  
• Post-H1N1 Narcolepsy-Cataplexy Dauvilliers, Y., Montplaisir, J., Cochen, V., Desautels, A., Einen, M., & Mignot, E. (2010). Post-H1N1 Narcolepsy-Cataplexy. SLEEP, 33(11), 1428-1430.
  
• DQB1*0602 predicts interindividual differences in physiologic sleep, sleepiness, and fatigue Goel, N., Banks, S., Mignot, E., & Dinges, D. F. (2010). DQB1*0602 predicts interindividual differences in physiologic sleep, sleepiness, and fatigue. NEUROLOGY, 75(17), 1509-1519.
  
• Circadian and Homeostatic Regulation of Structural Synaptic Plasticity in Hypocretin Neurons Appelbaum, L., Wang, G., Yokogawa, T., Skariah, G. M., Smith, S. J., & Mignot, E. (2010). Circadian and Homeostatic Regulation of Structural Synaptic Plasticity in Hypocretin Neurons. NEURON, 68(1), 87-98.
  
• Sleep Well and Stay Slim: Dream or Reality? Taheri, S., & Mignot, E. (2010). Sleep Well and Stay Slim: Dream or Reality?. ANNALS OF INTERNAL MEDICINE, 153(7), 475-?.
  
• Effects of sleep on the cardiovascular and thermoregulatory systems: a possible role for hypocretins Schwimmer, H., Stauss, H. M., Abboud, F., Nishino, S., Mignot, E., & Zeitzer, J. M. (2010). Effects of sleep on the cardiovascular and thermoregulatory systems: a possible role for hypocretins. JOURNAL OF APPLIED PHYSIOLOGY, 109(4), 1053-1063.
  
• Post-Streptococcal Auto-Antibodies Inhibit Protein Disulfide Isomerase and Are Associated with Insulin Resistance Aran, A., Weiner, K., Lin, L., Finn, L. A., Greco, M. A., & Mignot, E. (2010). Post-Streptococcal Auto-Antibodies Inhibit Protein Disulfide Isomerase and Are Associated with Insulin Resistance. PLOS ONE, 5(9).
  
• Anti-Tribbles Homo log 2 (TRIB2) Autoantibodies in Narcolepsy are Associated with Recent Onset of Cataplexy Kawashima, M., Lin, L., Tanaka, S., Jennum, P., Knudsen, S., & Mignot, E. (2010). Anti-Tribbles Homo log 2 (TRIB2) Autoantibodies in Narcolepsy are Associated with Recent Onset of Cataplexy. SLEEP, 33(7), 869-874.
  
• Narcolepsy with Cataplexy Associated with Holoprosencephaly Misdiagnosed as Epileptic Drop Attacks Plazzi, G., Tonon, C., Rubboli, G., Franceschini, C., Pizza, F., & Lodi, R. (2010). Narcolepsy with Cataplexy Associated with Holoprosencephaly Misdiagnosed as Epileptic Drop Attacks. MOVEMENT DISORDERS, 25(6), 788-790.
  
• Behavioural and neurophysiological correlates of human cataplexy: A video-polygraphic study Vetrugno, R., D'Angelo, R., Moghadam, K. K., Vandi, S., Franceschini, C., & Plazzi, G. (2010). Behavioural and neurophysiological correlates of human cataplexy: A video-polygraphic study. CLINICAL NEUROPHYSIOLOGY, 121(2), 153-162.
  
• Sodium oxybate is an effective and safe treatment for narcolepsy Lammers, G. J., Bassetti, C., Billiard, M., Black, J., Broughton, R., & Thorpy, M. (2010). Sodium oxybate is an effective and safe treatment for narcolepsy. SLEEP MEDICINE, 11(1), 105-106.
  
• Sleep-wake regulation and hypocretin-melatonin interaction in zebrafish Appelbaum, L., Wang, G. X., Maro, G. S., Mori, R., Tovin, A., & Mourrain, P. (2009). Sleep-wake regulation and hypocretin-melatonin interaction in zebrafish. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 106(51), 21942-21947.
  
• Characterization of Two Melanin-Concentrating Hormone Genes in Zebrafish Reveals Evolutionary and Physiological Links with the Mammalian MCH System Berman, J. R., Skariah, G., Maro, G. S., Mignot, E., & Mourrain, P. (2009). Characterization of Two Melanin-Concentrating Hormone Genes in Zebrafish Reveals Evolutionary and Physiological Links with the Mammalian MCH System. JOURNAL OF COMPARATIVE NEUROLOGY, 517(5), 695-710.
  
• T-box 3 is expressed in the adult mouse hypothalamus and medulla Eriksson, K. S., & Mignot, E. (2009). T-box 3 is expressed in the adult mouse hypothalamus and medulla. BRAIN RESEARCH, 1302, 233-239.
  
• Body Mass Index-Independent Metabolic Alterations in Narcolepsy with Cataplexy Poli, F., Plazzi, G., Di Dalmazi, G., Ribichini, D., Vicennati, V., & Pagotto, U. (2009). Body Mass Index-Independent Metabolic Alterations in Narcolepsy with Cataplexy. SLEEP, 32(11), 1491-1497.
  
• Modafinil and gamma-hydroxybutyrate have sleep state-specific pharmacological actions on hypocretin-1 physiology in a primate model of human sleep Zeitzer, J. M., Buckmaster, C. L., Landoltd, H.-P., Lyons, D. M., & Mignot, E. (2009). Modafinil and gamma-hydroxybutyrate have sleep state-specific pharmacological actions on hypocretin-1 physiology in a primate model of human sleep. BEHAVIOURAL PHARMACOLOGY, 20(7), 643-652.
  
• Distribution of neurochemical abnormalities in patients with narcolepsy with cataplexy: An in vivo brain proton MR spectroscopy study Tonon, C., Franceschini, C., Testa, C., Manners, D. N., Poli, F., & Plazzi, G. (2009). Distribution of neurochemical abnormalities in patients with narcolepsy with cataplexy: An in vivo brain proton MR spectroscopy study. BRAIN RESEARCH BULLETIN, 80(3), 147-150.
  
• Resting Our Cortices by Going DOWN to Sleep Mignot, E., & Huguenard, J. R. (2009). Resting Our Cortices by Going DOWN to Sleep. NEURON, 63(6), 719-721.
  
• Absence of ubiquitinated inclusions in hypocretin neurons of patients with narcolepsy Honda, M., Arai, T., Fukazawa, M., Honda, Y., Tsuchiya, K., & Mignot, E. (2009). Absence of ubiquitinated inclusions in hypocretin neurons of patients with narcolepsy. NEUROLOGY, 73(7), 511-517.
  
• Elevated Anti-Streptococcal Antibodies in Patients with Recent Narcolepsy Onset Aran, A., Lin, L., Nevsimalova, S., Plazzi, G., Hong, S. C., & Mignot, E. (2009). Elevated Anti-Streptococcal Antibodies in Patients with Recent Narcolepsy Onset. SLEEP, 32(8), 979-983.
  
• Decreased CSF Histamine in Narcolepsy With and Without Low CSF Hypocretin-1 in Comparison to Healthy Controls Nishino, S., Sakurai, E., Nevsimalova, S., Yoshida, Y., Watanabe, T., & Mignot, E. (2009). Decreased CSF Histamine in Narcolepsy With and Without Low CSF Hypocretin-1 in Comparison to Healthy Controls. SLEEP, 32(2), 175-180.
  
• HLA DQB1*0602 IS ASSOCIATED WITH SLEEP PERCEPTION IN OLDER INDIVIDUALS WITH INSOMNIA Zeitzer, J., Grove, M. E., Mignot, E., Yesavage, J. A., & Friedman, L. (2009). HLA DQB1*0602 IS ASSOCIATED WITH SLEEP PERCEPTION IN OLDER INDIVIDUALS WITH INSOMNIA. SLEEP, 32, A262-A262.
  
• Sympathetic and cardiovascular activity during cataplexy in narcolepsy. Donadio, V., Plazzi, G., Vandi, S., Franceschini, C., Karlsson, T., & Liguori, R. (2008). Sympathetic and cardiovascular activity during cataplexy in narcolepsy. Journal of sleep research, 17(4), 458-463.
  
• Variant between CPT1B and CHKB associated with susceptibility to narcolepsy Miyagawa, T., Kawashima, M., Nishida, N., Ohashi, J., Kimura, R., & Tokunaga, K. (2008). Variant between CPT1B and CHKB associated with susceptibility to narcolepsy. NATURE GENETICS, 40(11), 1324-1328.
  
• Intravenous high-dose immunoglobulin treatment in recent onset childhood narcolepsy with cataplexy Plazzi, G., Poli, F., Franceschini, C., Parmeggiani, A., Pirazzoli, P., & Montagna, P. (2008). Intravenous high-dose immunoglobulin treatment in recent onset childhood narcolepsy with cataplexy. JOURNAL OF NEUROLOGY, 255(10), 1549-1554.
  
• Hypocretin receptor expression in canine and murine narcolepsy models and in hypocretin-ligand deficient human narcolepsy Mishima, K., Fujiki, N., Yoshida, Y., Sakurai, T., Honda, M., & Nishino, S. (2008). Hypocretin receptor expression in canine and murine narcolepsy models and in hypocretin-ligand deficient human narcolepsy. SLEEP, 31(8), 1119-1126.
  
• CSF hypocretin-1 assessment in sleep and neurological disorders Bourgin, P., Zeitzer, J. M., & Mignot, E. (2008). CSF hypocretin-1 assessment in sleep and neurological disorders. LANCET NEUROLOGY, 7(7), 649-662.
  
• Anomalous Hypothalamic Responses to Humor in Cataplexy Reiss, A. L., Hoeft, F., Tenforde, A. S., Chen, W., Mobbs, D., & Mignot, E. J. (2008). Anomalous Hypothalamic Responses to Humor in Cataplexy. PLOS ONE, 3(5).
  
• Sleep and EEG features in genetic models of Down syndrome Colas, D., Valletta, J. S., Takimoto-Kimura, R., Nishino, S., Fujiki, N., & Mignot, E. (2008). Sleep and EEG features in genetic models of Down syndrome. NEUROBIOLOGY OF DISEASE, 30(1), 1-7.
  
• Excessive daytime sleepiness: Population and etiology versus nosology Mignot, E. (2008). Excessive daytime sleepiness: Population and etiology versus nosology. SLEEP MEDICINE REVIEWS, 12(2), 87-94.
  
• The type III neurofilament peripherin is expressed in the tuberomammillary neurons of the mouse Eriksson, K. S., Zhang, S., Lin, L., Lariviere, R. C., Julien, J.-P., & Mignot, E. (2008). The type III neurofilament peripherin is expressed in the tuberomammillary neurons of the mouse. BMC NEUROSCIENCE, 9.
  
• The hypocretin neurotransmission system in myotonic dystrophy type 1 Ciafaloni, E., Mignot, E., Sansone, V., Hilbert, J. E., Lin, L., & Thornton, C. A. (2008). The hypocretin neurotransmission system in myotonic dystrophy type 1. NEUROLOGY, 70(3), 226-230.
  
• Hypocretin neuron morphology and neurotransmitter identity in zebrafish Appelbaum, L., Wang, G., Marin, W., Mignot, E., & Mourrain, P. (2008). Hypocretin neuron morphology and neurotransmitter identity in zebrafish. SLEEP, 31, A5-A5.
  
• Insulin-like growth factor binding protein-3 reduces hypocretin/orexin transmission Zhang, S., Lin, L., Zhang, J., Tanaka, S., Honda, M., & Mignot, E. (2008). Insulin-like growth factor binding protein-3 reduces hypocretin/orexin transmission. SLEEP, 31, A16-A17.
  
• REM behavior disorder (RBD) can be one of the first symptoms of childhood narcolepsy Nevsimalova, S., Prihodova, I., Kemlink, D., Lin, L., & Mignot, E. (2007). REM behavior disorder (RBD) can be one of the first symptoms of childhood narcolepsy. SLEEP MEDICINE, 8(7-8), 784-786.
  
• Comparative expression of p2x receptors and ecto-nucleoside triphosphate diphosphohydrolase 3 in hypocretin and sensory neurons in zebrafish Appelbaum, L., Skariah, G., Mourrain, P., & Mignot, E. (2007). Comparative expression of p2x receptors and ecto-nucleoside triphosphate diphosphohydrolase 3 in hypocretin and sensory neurons in zebrafish. BRAIN RESEARCH, 1174, 66-75.
  
• Increasing length of wakefulness and modulation of hypocretin-1 in the wake-consolidated squirrel monkey Zeitzer, J. M., Buckmaster, C. L., Lyons, D. M., & Mignot, E. (2007). Increasing length of wakefulness and modulation of hypocretin-1 in the wake-consolidated squirrel monkey. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY, 293(4), R1736-R1742.
  
• Characterization of sleep in zebrafish and insomnia in hypocretin receptor mutants Yokogawa, T., Marin, W., Faraco, J., Pezeron, G., Appelbaum, L., & Mignot, E. (2007). Characterization of sleep in zebrafish and insomnia in hypocretin receptor mutants. PLOS BIOLOGY, 5(10), 2379-2397.
  
• Depression: relationships to sleep paralysis and other sleep disturbances in a community sample Szklo-Coxe, M., Young, T., Finn, L., & Mignot, E. (2007). Depression: relationships to sleep paralysis and other sleep disturbances in a community sample. JOURNAL OF SLEEP RESEARCH, 16(3), 297-312.
  
• The development of hypocretin (orexin) deficiency in hypocretin/ataxin-3 transgenic rats Zhang, S., Lin, L., Kaur, S., Thankachan, S., Blanco-Centurion, C., & Shiromani, P. J. (2007). The development of hypocretin (orexin) deficiency in hypocretin/ataxin-3 transgenic rats. NEUROSCIENCE, 148(1), 34-43.
  
• A step forward for restless legs syndrome Mignot, E. (2007). A step forward for restless legs syndrome. NATURE GENETICS, 39(8), 938-939.
  
• Correlates of serum C-reactive protein (CRP) - No association with sleep duration or sleep disordered breathing Taheri, S., Austin, D., Lin, L., Nieto, F. J., Young, T., & Mignot, E. (2007). Correlates of serum C-reactive protein (CRP) - No association with sleep duration or sleep disordered breathing. SLEEP, 30(8), 991-996.
  
• Sleep/wake fragmentation disrupts metabolism in a mouse model of narcolepsy Zhang, S., Zeitzer, J. M., Sakurai, T., Nishino, S., & Mignot, E. (2007). Sleep/wake fragmentation disrupts metabolism in a mouse model of narcolepsy. JOURNAL OF PHYSIOLOGY-LONDON, 581(2), 649-663.
  
• Reduced expression of TACI, PENK and SOCS2 in Hcrtr-2 mutated narcoleptic dog brain Lindberg, J., Saetre, P., Nishino, S., Mignot, E., & Jazin, E. (2007). Reduced expression of TACI, PENK and SOCS2 in Hcrtr-2 mutated narcoleptic dog brain. BMC NEUROSCIENCE, 8.
  
• English translations of the first clinical reports on narcolepsy and cataplexy by Westphal and Gélineau in the late 19th century, with commentary. Schenck, C. H., Bassetti, C. L., Arnulf, I., & Mignot, E. (2007). English translations of the first clinical reports on narcolepsy and cataplexy by Westphal and Gélineau in the late 19th century, with commentary. Journal of clinical sleep medicine , 3(3), 301-311.
  
• Normal cerebrospinal fluid levels of hypocretin-1 (orexin A) in patients with fibromyalgia syndrome Taiwo, O. B., Russell, I. J., Mignot, E., Lin, L., Michalek, J. E., & Larson, A. A. (2007). Normal cerebrospinal fluid levels of hypocretin-1 (orexin A) in patients with fibromyalgia syndrome. SLEEP MEDICINE, 8(3), 260-265.
  
• Genomic and functional conservation of sedative-hypnotic targets in the zebrafish Renier, C., Faraco, J. H., Bourgin, P., Motley, T., Bonaventure, P., & Mignot, E. (2007). Genomic and functional conservation of sedative-hypnotic targets in the zebrafish. PHARMACOGENETICS AND GENOMICS, 17(4), 237-253.
  
• Analysis of extended HLA haplotypes in multiple sclerosis and narcolepsy families confirms a predisposing effect for the class I region in Tasmanian MS patients Rubio, J. P., Bahlo, M., Stankovich, J., Burfoot, R. K., Johnson, L. J., & Foote, S. J. (2007). Analysis of extended HLA haplotypes in multiple sclerosis and narcolepsy families confirms a predisposing effect for the class I region in Tasmanian MS patients. IMMUNOGENETICS, 59(3), 177-186.
  
• Narcolepsy with cataplexy Dauvilliers, Y., Amulf, I., & Mignot, E. (2007). Narcolepsy with cataplexy. LANCET, 369(9560), 499-511.
  
• A circadian sleep disorder reveals a complex clock Mignot, E., & Takahashi, J. S. (2007). A circadian sleep disorder reveals a complex clock. CELL, 128(1), 22-23.
  
• DQB1*0301 and DQB1*0601 modulate narcolepsy susceptibility in Koreans Hong, S.-C., Lin, L., Lo, B., Jeong, J.-H., Shin, Y.-K., & Mignot, E. (2007). DQB1*0301 and DQB1*0601 modulate narcolepsy susceptibility in Koreans. HUMAN IMMUNOLOGY, 68(1), 59-68.
  
• Identification of novel transcripts expressed in hypocretin-containing neurons Bourgin, P., Lin, L., Priest, M., Renier, C., Sakurai, T., & Mignot, E. (2007). Identification of novel transcripts expressed in hypocretin-containing neurons. SLEEP, 30, A223-A223.
  
• A study of the diagnostic utility of HLA typing, CSF hypocretin-1 measurements, and MSLT testing for the diagnosis of narcolepsy in 163 Korean patients with unexplained excessive daytime sleepiness Hong, S., Lin, L., Jeong, J., Shin, Y., Han, J., & Mignot, E. (2007). A study of the diagnostic utility of HLA typing, CSF hypocretin-1 measurements, and MSLT testing for the diagnosis of narcolepsy in 163 Korean patients with unexplained excessive daytime sleepiness. SLEEP, 30, A214-A214.
  
• Hypocretin-1 is inversely associated with wake fragmentation in Alzheimer's disease Zeitzer, J., Friedman, L., Lin, L., Mignot, E., Peskind, E., & Yesavage, J. (2007). Hypocretin-1 is inversely associated with wake fragmentation in Alzheimer's disease. SLEEP, 30, A302-A302.
  
• A novel candidate gene for narcolepsy colocalized in human and mouse hypocretin/orexin neurons Honda, M., Eriksson, K., Lin, L., Salehi, A., Tanaka, S., & Mignot, E. (2007). A novel candidate gene for narcolepsy colocalized in human and mouse hypocretin/orexin neurons. SLEEP, 30, A218-A218.
  
• Different periodicity and time structure of leg movements during sleep in narcolepsy/cataplexy and restless legs syndrome Ferri, R., Zucconi, M., Manconi, M., Bruni, O., Ferini-Strambi, L., & Plazzi, G. (2006). Different periodicity and time structure of leg movements during sleep in narcolepsy/cataplexy and restless legs syndrome. SLEEP, 29(12), 1587-1594.
  
• A study of the diagnostic utility of HLA typing, CSF hypocretin-1 measurements, and MSLT testing for the diagnosis of narcolepsy in 163 Korean patients with unexplained excessive daytime sleepiness Hong, S.-C., Lin, L., Jeong, J.-H., Shin, Y.-K., Han, J.-H., & Mignot, E. (2006). A study of the diagnostic utility of HLA typing, CSF hypocretin-1 measurements, and MSLT testing for the diagnosis of narcolepsy in 163 Korean patients with unexplained excessive daytime sleepiness. SLEEP, 29(11), 1429-1438.
  
• Regulation of hypocretin (orexin) expression in embryonic zebrafish Faraco, J. H., Appelbaum, L., Marin, W., Gaus, S. E., Mourrain, P., & Mignot, E. (2006). Regulation of hypocretin (orexin) expression in embryonic zebrafish. JOURNAL OF BIOLOGICAL CHEMISTRY, 281(40), 29753-29761.
  
• CSF versus serum leptin in narcolepsy: Is there an effect of hypocretin deficiency? Arnulf, I., Lin, L., Zhang, J., Russell, I. J., Ripley, B., & Mignot, E. (2006). CSF versus serum leptin in narcolepsy: Is there an effect of hypocretin deficiency?. SLEEP, 29(8), 1017-1024.
  
• The neurobiology of hypocretins (orexins), narcolepsy and related therapeutic interventions Zeitzer, J. M., Nishin, S., & Mignot, E. (2006). The neurobiology of hypocretins (orexins), narcolepsy and related therapeutic interventions. TRENDS IN PHARMACOLOGICAL SCIENCES, 27(7), 368-374.
  
• Narcolepsy-cataplexy associated with precocious puberty Plazzi, G., Parmeggiani, A., Mignot, E., Lin, L., Scano, M. C., & Cicognani, A. (2006). Narcolepsy-cataplexy associated with precocious puberty. NEUROLOGY, 66(10), 1577-1579.
  
• Gene expression profiling in postmortem posterior hypothalamic tissue reveals narcolepsy specific genes Honda, M., Eriksson, K., Salehi, A., Hesla, P., Maehlen, J., & Mignot, E. (2006). Gene expression profiling in postmortem posterior hypothalamic tissue reveals narcolepsy specific genes. SLEEP, 29, A219-A219.
  
• HLA-DQB1*0602 and hypocretin in Korean narcoleptics with cataplexy Hong, S., Jeong, J., Han, J., Lee, S., & Mignot, E. (2006). HLA-DQB1*0602 and hypocretin in Korean narcoleptics with cataplexy. SLEEP, 29, A221-A221.
  
• CSF hypocretin levels are normal in Huntington's disease patients Gaus, S. E., Lin, L., & Mignot, E. (2005). CSF hypocretin levels are normal in Huntington's disease patients. SLEEP, 28(12), 1607-1608.
  
• Kleine-Levin syndrome: a systematic review of 186 cases in the literature Arnulf, I., Zeitzer, J. M., File, J., Farber, N., & Mignot, E. (2005). Kleine-Levin syndrome: a systematic review of 186 cases in the literature. BRAIN, 128, 2763-2776.
  
• Concomitant loss of dynorphin, NARP, and orexin in narcolepsy Crocker, A., Espana, R. A., Papadopoulou, M., SAPER, C. B., Faraco, J., & Scammell, T. E. (2005). Concomitant loss of dynorphin, NARP, and orexin in narcolepsy. NEUROLOGY, 65(8), 1184-1188.
  
• A link between short sleep and obesity: Building the evidence for causation Cizza, G., Skarulis, M., & Mignot, E. (2005). A link between short sleep and obesity: Building the evidence for causation. SLEEP, 28(10), 1217-1220.
  
• Late-onset narcolepsy presenting as rapidly progressing muscle weakness: Response to plasmapheresis Chen, W., Black, J., Call, P., & Mignot, E. (2005). Late-onset narcolepsy presenting as rapidly progressing muscle weakness: Response to plasmapheresis. ANNALS OF NEUROLOGY, 58(3), 489-490.
  
• Hypocretin-1 (orexin A) deficiency in acute traumatic brain injury Baumann, C. R., Stocker, R., Imhof, H. G., Trentz, O., Hersberger, M., & Bassetti, C. L. (2005). Hypocretin-1 (orexin A) deficiency in acute traumatic brain injury. NEUROLOGY, 65(1), 147-149.
  
• Polymorphisms within the canine MLPH gene are associated with dilute coat color in dogs Philipp, U., Hamann, H., Mecklenburg, L., Nishino, S., Mignot, E., & Leeb, T. (2005). Polymorphisms within the canine MLPH gene are associated with dilute coat color in dogs. BMC GENETICS, 6.
  
• Emerging therapies in narcolepsy-cataplexy Mignot, E., & Nishino, S. (2005). Emerging therapies in narcolepsy-cataplexy. SLEEP, 28(6), 754-763.
  
• History of the development of sleep medicine in the United States. Shepard, J. W., Buysse, D. J., Chesson, A. L., Dement, W. C., Goldberg, R., & White, D. P. (2005). History of the development of sleep medicine in the United States. Journal of clinical sleep medicine , 1(1), 61-82.
  
• HLA expression in narcoleptic hypothalamus Honda, M., Salehi, A., Hesla, P., Maehlen, J., Gaus, S., & Mignot, E. (2005). HLA expression in narcoleptic hypothalamus. SLEEP, 28, A220-A220.
  
• Hypocretin deficiency in Prader-Willi syndrome Nevsimalova, S., Vankova, J., Stepanova, I., Seemanova, E., Mignot, E., & Nishino, S. (2005). Hypocretin deficiency in Prader-Willi syndrome. EUROPEAN JOURNAL OF NEUROLOGY, 12(1), 70-72.
  
• Cataplexy and frequency of HLA-DQB1*0602 in Korean narcoleptics Hong, S., Jeong, J., Han, J., Lee, S., & Mignot, E. (2005). Cataplexy and frequency of HLA-DQB1*0602 in Korean narcoleptics. SLEEP, 28, A218-A218.
  
• Angiotensin-converting enzyme, sleep-disordered breathing, and hypertension Lin, L., Finn, L., Zhang, J., Young, T., & Mignot, E. (2004). Angiotensin-converting enzyme, sleep-disordered breathing, and hypertension. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 170(12), 1349-1353.
  
• Sodium oxybate for excessive daytime sleepiness in narcolepsy-cataplexy Arnulf, I., & Mignot, E. (2004). Sodium oxybate for excessive daytime sleepiness in narcolepsy-cataplexy. SLEEP, 27(7), 1242-1243.
  
• APOE epsilon 4 is associated with obstructive sleep apnea/hypopnea - The Sleep Heart Health Study Gottlieb, D. J., DeStefano, A. L., Foley, D. J., Mignot, E., Redline, S., & Young, T. (2004). APOE epsilon 4 is associated with obstructive sleep apnea/hypopnea - The Sleep Heart Health Study. NEUROLOGY, 63(4), 664-668.
  
• The diurnal rhythm of hypocretin in young and old F344 rats Desarnaud, F., Murillo-Rodriguez, E., Lin, L., Xu, M., Gerashchenko, D., & Shiromani, P. J. (2004). The diurnal rhythm of hypocretin in young and old F344 rats. SLEEP, 27(5), 851-856.
  
• The effect of hypocretin replacement therapy in a 3-year-old Weimaraner with narcolepsy Schatzberg, S. J., Cutter-Schatzberg, K., Nydam, D., Barrett, J., Penn, R., & Mignot, E. (2004). The effect of hypocretin replacement therapy in a 3-year-old Weimaraner with narcolepsy. JOURNAL OF VETERINARY INTERNAL MEDICINE, 18(4), 586-588.
  
• Lesions of the suprachiasmatic nucleus eliminate the daily rhythm of hypocretin-1 release Zhang, S. W., Zeitzer, J. M., Yoshida, Y., Wisor, J. P., Nishino, S., & Mignot, E. (2004). Lesions of the suprachiasmatic nucleus eliminate the daily rhythm of hypocretin-1 release. SLEEP, 27(4), 619-627.
  
• Locomotor-dependent and -independent components to hypocretin-1 (orexinA) regulation in sleep-wake consolidating monkeys Zeitzer, J. M., Buckmaster, C. L., Lyons, D. M., & Mignot, E. (2004). Locomotor-dependent and -independent components to hypocretin-1 (orexinA) regulation in sleep-wake consolidating monkeys. JOURNAL OF PHYSIOLOGY-LONDON, 557(3), 1045-1053.
  
• Sleep, sleep disorders and hypocretin (orexin) Mignot, E. (2004). Sleep, sleep disorders and hypocretin (orexin). SLEEP MEDICINE, 5, S2-S8.
  
• The roles of midbrain and diencephalic dopamine cell groups in the regulation of cataplexy in narcoleptic Dobermans Okura, M., Fujiki, N., Kita, L., Honda, K., Yoshida, Y., & Nishino, S. (2004). The roles of midbrain and diencephalic dopamine cell groups in the regulation of cataplexy in narcoleptic Dobermans. NEUROBIOLOGY OF DISEASE, 16(1), 274-282.
  
• Undetectable CSF hypocretin-1 in "Hashimoto's encephalopathy" associated with coma Castillo, P. R., Mignot, E., Woodruff, B. K., & Boeve, B. F. (2004). Undetectable CSF hypocretin-1 in "Hashimoto's encephalopathy" associated with coma. NEUROLOGY, 62(10), 1909-1909.
  
• Hypocretin-1 CSF levels in anti-Ma2 associated encephalitis Overeem, S., Dalmau, J., Bataller, L., Nishino, S., Mignot, E., & Lammers, G. J. (2004). Hypocretin-1 CSF levels in anti-Ma2 associated encephalitis. NEUROLOGY, 62(1), 138-140.
  
• Increased hypocretin-1 levels in cerebrospinal fluid after REM sleep deprivation Pedrazzoli, M., D'Almeida, V., Martins, P. Jf., Machado, R. B., Ling, L., & Mignot, E. (2004). Increased hypocretin-1 levels in cerebrospinal fluid after REM sleep deprivation. BRAIN RESEARCH, 995(1), 1-6.
  
• Mapping multiple sclerosis susceptibility to the HLA-DR locus in African Americans Oksenberg, J. R., Barcellos, L. F., Cree, B. Ac., Baranzini, S. E., Bugawan, T. L., & Hauser, S. L. (2004). Mapping multiple sclerosis susceptibility to the HLA-DR locus in African Americans. AMERICAN JOURNAL OF HUMAN GENETICS, 74(1), 160-167.
  
• Clinical features and frequency of HLA-DQB1*0602 in Korean narcolepsy patients Hong, S., Jeong, J., Han, J., Lee, S., & Mignot, E. (2004). Clinical features and frequency of HLA-DQB1*0602 in Korean narcolepsy patients. SLEEP, 27, 242-242.
  
• Genes transcripts relating to the immune response are up-regulated in narcoleptic postmortem hypothalamus using microarray Honda, M., Salehi, A., Hesla, P., Maehlen, J., Gaus, S., & Mignot, E. (2004). Genes transcripts relating to the immune response are up-regulated in narcoleptic postmortem hypothalamus using microarray. SLEEP, 27, 250-251.
  
• Diurnal variations of CSF hypocretin (HCRT) and changes in gene expression as detected by microarrays in young and old rats Desarnaud, F., Murillo-Rodriguez, E., Xu, M., Gerashenko, D., Lu, J., & Shiromani, P. (2004). Diurnal variations of CSF hypocretin (HCRT) and changes in gene expression as detected by microarrays in young and old rats. SLEEP, 27, 382-382.
  
• Normal CSF hypocretin-1 (orexin A) levels in dementia with Lewy bodies associated with excessive daytime sleepiness Baumann, C. R., Dauvilliers, Y., Mignot, E., & Bassetti, C. L. (2004). Normal CSF hypocretin-1 (orexin A) levels in dementia with Lewy bodies associated with excessive daytime sleepiness. EUROPEAN NEUROLOGY, 52(2), 73-76.
  
• Effects of IV and ICV hypocretin-1 (Orexin A) in hypocretin receptor-2 gene mutated narcoleptic dogs and IV hypocretin-1 replacement therapy in a hypocretin-ligand-deficient narcoleptic dog Fujiki, N., Yoshida, Y., Ripley, B., Mignot, E., & Nishino, S. (2003). Effects of IV and ICV hypocretin-1 (Orexin A) in hypocretin receptor-2 gene mutated narcoleptic dogs and IV hypocretin-1 replacement therapy in a hypocretin-ligand-deficient narcoleptic dog. SLEEP, 26(8), 953-959.
  
• Normal hypocretin-1 levels in the cerebrospinal fluid of patients with fatal familial insomnia Martinez-Rodriguez, J. E., Sanchez-Valle, R., Saiz, A., Lin, L., Iranzo, A., & Santamaria, J. (2003). Normal hypocretin-1 levels in the cerebrospinal fluid of patients with fatal familial insomnia. SLEEP, 26(8), 1068-1068.
  
• Relationship between CSF hypocretin levels and hypocretin neuronal loss Gerashchenko, D., Munillo-Rodriguez, E., Lin, L., Xu, M., Hallett, L., & Shiromani, P. J. (2003). Relationship between CSF hypocretin levels and hypocretin neuronal loss. EXPERIMENTAL NEUROLOGY, 184(2), 1010-1016.
  
• CSF hypocretin-1 levels in restless legs syndrome Stiasny-Kolster, K., Mignot, E., Ling, L., Moller, J. C., Cassel, W., & Oertel, W. H. (2003). CSF hypocretin-1 levels in restless legs syndrome. NEUROLOGY, 61(10), 1426-1429.
  
• Report of a case of immunosuppression with prednisone in an 8-year-old boy with an acute onset of hypocretin-deficiency narcolepsy Hecht, M., Lin, L., Kushida, C. A., Umetsu, D. T., Taheri, S., & Mignot, E. (2003). Report of a case of immunosuppression with prednisone in an 8-year-old boy with an acute onset of hypocretin-deficiency narcolepsy. SLEEP, 26(7), 809-810.
  
• Narcolepsy: involvement of imprinted, differentially-methylated promotor haplotypes of vesicular monoamine transporter 2 (VMAT2). Drgon, T., Takahashi, M., Walther, D., Lin, Z., Lin, L., & Uhl, G. R. (2003). Narcolepsy: involvement of imprinted, differentially-methylated promotor haplotypes of vesicular monoamine transporter 2 (VMAT2). AMERICAN JOURNAL OF HUMAN GENETICS, 73(5), 332-332.
  
• CSF hypocretin levels in Guillain-Barre syndrome and other inflammatory neuropathies Nishino, S., Kanbayashi, T., Fujiki, N., Uchino, M., Ripley, B., & Mignot, E. (2003). CSF hypocretin levels in Guillain-Barre syndrome and other inflammatory neuropathies. NEUROLOGY, 61(6), 823-825.
  
• On the value of measuring CSF hypocretin-1 in diagnosing narcolepsy Mignot, E., Chen, W., & Black, J. (2003). On the value of measuring CSF hypocretin-1 in diagnosing narcolepsy. SLEEP, 26(6), 646-649.
  
• Diurnal variation of cerebrospinal fluid hypocretin-1 (orexin-A) levels in control and depressed subjects Salomon, R. M., Ripley, B., Kennedy, J. S., Johnson, B., Schmidt, D., & Mignot, E. (2003). Diurnal variation of cerebrospinal fluid hypocretin-1 (orexin-A) levels in control and depressed subjects. BIOLOGICAL PSYCHIATRY, 54(2), 96-104.
  
• Sleep disturbances and hypocretin deficiency in Niemann-Pick disease type C Vankova, J., Stepanova, I., Jech, R., Elleder, M., Ling, L., & Nevsimalova, S. (2003). Sleep disturbances and hypocretin deficiency in Niemann-Pick disease type C. SLEEP, 26(4), 427-430.
  
• Investigation of the autoimmune basis of narcolepsy using western blot analysis of lateral hypothalamus protein extract with serum and cerebrospinal fluid (CSF) Taheri, S., Krempetz, M., Jackson, M., Paterno, J., & Mignot, E. (2003). Investigation of the autoimmune basis of narcolepsy using western blot analysis of lateral hypothalamus protein extract with serum and cerebrospinal fluid (CSF). SLEEP, 26, A285-A285.
  
• CSF hypocretin levels in Korean narcoleptic patients Hong, S., Jeong, J. H., Han, J. H., Lee, S. P., & Mignot, E. (2003). CSF hypocretin levels in Korean narcoleptic patients. SLEEP, 26, A284-A284.
  
• Circadian and homeostatic regulation of hypocretin in a primate model: Implications for the consolidation of wakefulness Zeitzer, J. M., Buckmaster, C. L., Parker, K. J., Hauck, C. M., Lyons, D. M., & Mignot, E. (2003). Circadian and homeostatic regulation of hypocretin in a primate model: Implications for the consolidation of wakefulness. JOURNAL OF NEUROSCIENCE, 23(8), 3555-3560.
  
• Voxel-based morphometry in hypocretin-deficient narcolepsy Overeem, S., Steens, S. Ca., Good, C. D., Ferrari, M. D., Mignot, E., & Lammers, G. J. (2003). Voxel-based morphometry in hypocretin-deficient narcolepsy. SLEEP, 26(1), 44-46.
  
• Sleeping with the hypothalamus: emerging therapeutic targets for sleep disorders Mignot, E., Taheri, S., & Nishino, S. (2002). Sleeping with the hypothalamus: emerging therapeutic targets for sleep disorders. NATURE NEUROSCIENCE, 5, 1071-1075.
  
• Future of genetics of mood disorders research. Merikangas, K. R., Chakravarti, A., Moldin, S. O., Araj, H., Blangero, J. C., & Takahashi, J. S. (2002). Future of genetics of mood disorders research. Biological psychiatry, 52(6), 457-477.
  
• Increased CSF hypocretin-1 (orexin-A) in restless legs syndrome Allen, R. P., Mignot, E., Ripley, B., Nishino, S., & Earley, C. J. (2002). Increased CSF hypocretin-1 (orexin-A) in restless legs syndrome. NEUROLOGY, 59(4), 639-641.
  
• HLA and hypocretin studies in Korean patients with narcolepsy Hong, S. C., Leen-Kim, Park, S. A., Han, J. H., Lee, S. P., & Mignot, E. (2002). HLA and hypocretin studies in Korean patients with narcolepsy. SLEEP, 25(4), 440-444.
  
• Hypocretin stimulates [(35)]GTP gamma S binding in Hcrtr 2-transfected cell lines and in brain homogenate Shiba, T., Ozu, M., Yoshida, Y., Mignot, E., & Nishino, S. (2002). Hypocretin stimulates [(35)]GTP gamma S binding in Hcrtr 2-transfected cell lines and in brain homogenate. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 294(3), 615-620.
  
• CSF hypocretin-1 levels in schizophrenics and controls: relationship to sleep architecture Nishino, S., Ripley, B., Mignot, E., Benson, K. L., & Zarcone, V. P. (2002). CSF hypocretin-1 levels in schizophrenics and controls: relationship to sleep architecture. PSYCHIATRY RESEARCH, 110(1), 1-7.
  
• Diurnal variation of CSF hypocretin-1 (orexin A) levels in control and depressed subjects Salomon, R. M., Ripley, B., Kennedy, J. S., Schmidt, D., Zeitzer, J., & Mignot, E. (2002). Diurnal variation of CSF hypocretin-1 (orexin A) levels in control and depressed subjects. SLEEP, 25, A12-A13.
  
• Stimulant medication usage in a large cohort of narcoleptic subjects Okun, M. L., Lopez, A., Colrain, I., Ginney, C., Brooks, S., & Black, J. (2002). Stimulant medication usage in a large cohort of narcoleptic subjects. SLEEP, 25, A474-A474.
  
• Clinical aspects of narcolepsy-cataplexy across ethnic groups Okun, M. L., Lin, L., Pelin, Z., Hong, S. C., & Mignot, E. (2002). Clinical aspects of narcolepsy-cataplexy across ethnic groups. SLEEP, 25(1), 27-35.
  
• The role of hypocretins (orexins) in sleep regulation and narcolepsy Taheri, S., Zeitzer, J. M., & Mignot, E. (2002). The role of hypocretins (orexins) in sleep regulation and narcolepsy. ANNUAL REVIEW OF NEUROSCIENCE, 25, 283-313.
  
• CSF hypocretin/orexin levels in narcolepsy and other neurological conditions Ripley, B., Overeem, S., Fujiki, N., Nevsimalova, S., Uchino, M., & Nishino, S. (2001). CSF hypocretin/orexin levels in narcolepsy and other neurological conditions. NEUROLOGY, 57(12), 2253-2258.
  
• Polymorphisms in the vicinity of the hypocretin/orexin are not associated with human narcolepsy Hungs, M., Lin, L., Okun, M., & Mignot, E. (2001). Polymorphisms in the vicinity of the hypocretin/orexin are not associated with human narcolepsy. NEUROLOGY, 57(10), 1893-1895.
  
• Decreased brain histamine content in hypocretin/orexin receptor-2 mutated narcoleptics dogs Nishino, S., Fujiki, N., Ripley, B., SAKURAI, E., Kato, M., & Yanai, K. (2001). Decreased brain histamine content in hypocretin/orexin receptor-2 mutated narcoleptics dogs. NEUROSCIENCE LETTERS, 313(3), 125-128.
  
• A commentary on the neurobiology of the hypocretin/orexin system Mignot, E. (2001). A commentary on the neurobiology of the hypocretin/orexin system. NEUROPSYCHOPHARMACOLOGY, 25, S5-S13.
  
• Fluctuation of extracellular hypocretin-1 (orexin A) levels in the rat in relation to the light-dark cycle and sleep-wake activities Yoshida, Y., Fujiki, N., Nakajima, T., Ripley, B., Matsumura, H., & Nishino, S. (2001). Fluctuation of extracellular hypocretin-1 (orexin A) levels in the rat in relation to the light-dark cycle and sleep-wake activities. EUROPEAN JOURNAL OF NEUROSCIENCE, 14(7), 1075-1081.
  
• Narcolepsy and the HLA region Lin, L., Hungs, M., & Mignot, E. (2001). Narcolepsy and the HLA region. JOURNAL OF NEUROIMMUNOLOGY, 117(1-2), 9-20.
  
• Narcolepsy and low CSF orexin (hypocretin) concentration after a diencephalic stroke Scammell, T. E., Nishino, S., Mignot, E., & SAPER, C. B. (2001). Narcolepsy and low CSF orexin (hypocretin) concentration after a diencephalic stroke. NEUROLOGY, 56(12), 1751-1753.
  
• Association between apolipoprotein E epsilon 4 and sleep-disordered breathing in adults KADOTANI, H., Kadotani, T., Young, T., Peppard, P. E., Finn, L., & Mignot, E. (2001). Association between apolipoprotein E epsilon 4 and sleep-disordered breathing in adults. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 285(22), 2888-2890.
  
• Hypocretin levels in sporadic and familial cases of canine narcolepsy Ripley, B., Fujiki, N., Okura, M., Mignot, E., & Nishino, S. (2001). Hypocretin levels in sporadic and familial cases of canine narcolepsy. NEUROBIOLOGY OF DISEASE, 8(3), 525-534.
  
• Narcoleptic canines display periodic leg movements during sleep Okura, M., Fujiki, N., Ripley, B., Takahashi, S., Amitai, N., & Nishino, S. (2001). Narcoleptic canines display periodic leg movements during sleep. PSYCHIATRY AND CLINICAL NEUROSCIENCES, 55(3), 243-244.
  
• Hypocretin/orexin, sleep and narcolepsy Hungs, M., & Mignot, E. (2001). Hypocretin/orexin, sleep and narcolepsy. BIOESSAYS, 23(5), 397-408.
  
• Physical and radiation hybrid mapping of canine chromosome 12, in a region corresponding to human chromosome 6p12-q12 Li, R., Faraco, J. H., Lin, L., Lin, X. Y., Hinton, L., & Mignot, E. (2001). Physical and radiation hybrid mapping of canine chromosome 12, in a region corresponding to human chromosome 6p12-q12. GENOMICS, 73(3), 299-315.
  
• Changes in CSF hypocretin-1 (orexin A) levels in rats across 24 hours and in response to food deprivation Fujiki, N., Yoshida, Y., Ripley, B., Honda, K., Mignot, E., & Nishino, S. (2001). Changes in CSF hypocretin-1 (orexin A) levels in rats across 24 hours and in response to food deprivation. NEUROREPORT, 12(5), 993-997.
  
• Diagnostic value of low CSF hypocretin/orexin levels in human narcolepsy Nishino, S., Ripley, B., Overeem, S., Nevsimalova, S., Lammers, G. J., & Mignot, E. (2001). Diagnostic value of low CSF hypocretin/orexin levels in human narcolepsy. SLEEP, 24, A95-A96.
  
• The comparability of the Stanford Sleep Inventory and the Sleep-EVAL system in narcolepsy diagnosis Okun, M. L., Ohayon, M. M., & Mignot, E. (2001). The comparability of the Stanford Sleep Inventory and the Sleep-EVAL system in narcolepsy diagnosis. SLEEP, 24, A328-A329.
  
• The narcolepsy diagnosis: Comparison between the Sleep-EVAL system and clinicians Black, J., Ohayon, M., Okun, M., Guilleminault, C., Mignot, E., & Zarcone, V. (2001). The narcolepsy diagnosis: Comparison between the Sleep-EVAL system and clinicians. SLEEP, 24, A328-A328.
  
• A hundred years of narcolepsy research Mignot, E. (2001). A hundred years of narcolepsy research. ARCHIVES ITALIENNES DE BIOLOGIE, 139(3), 207-220.
  
• Identification and functional analysis of mutations in the Hypocretin (Orexin) genes of narcoleptic canines Hungs, M., Fan, J., Lin, L., Lin, X. Y., Maki, R. A., & Mignot, E. (2001). Identification and functional analysis of mutations in the Hypocretin (Orexin) genes of narcoleptic canines. GENOME RESEARCH, 11(4), 531-539.
  
• Narcolepsy: Clinical features, new pathophysiologic insights, and future perspectives Overeem, S., Mignot, E., van Dijk, J. G., & Lammers, G. J. (2001). Narcolepsy: Clinical features, new pathophysiologic insights, and future perspectives. JOURNAL OF CLINICAL NEUROPHYSIOLOGY, 18(2), 78-105.
  
• Dopaminergic role in stimulant-induced wakefulness Wisor, J. P., Nishino, S., Sora, I., Uhl, G. H., Mignot, E., & Edgar, D. M. (2001). Dopaminergic role in stimulant-induced wakefulness. JOURNAL OF NEUROSCIENCE, 21(5), 1787-1794.
  
• The role of histamine in a hypocretin (orexin)-deficient sleep disorder, narcolepsy Nishino, S., Honda, K., Fujiki, N., Wurts, S. W., SAKURAI, E., & Yanai, K. (2001). The role of histamine in a hypocretin (orexin)-deficient sleep disorder, narcolepsy. HISTAMINE RESEARCH IN THE NEW MILLENNIUM, 1224, 247-251.
  
• Is narcolepsy a REM sleep disorder? Analysis of sleep abnormalities in narcoleptic Dobermans Nishino, S., Riehl, J., Hong, J., Kwan, M., REID, M., & Mignot, E. (2000). Is narcolepsy a REM sleep disorder? Analysis of sleep abnormalities in narcoleptic Dobermans. NEUROSCIENCE RESEARCH, 38(4), 437-446.
  
• Sulpiride, a D2/D3 blocker, reduces cataplexy but not REM sleep in canine narcolepsy Okura, M., Riehl, J., Mignot, E., & Nishino, S. (2000). Sulpiride, a D2/D3 blocker, reduces cataplexy but not REM sleep in canine narcolepsy. NEUROPSYCHOPHARMACOLOGY, 23(5), 528-538.
  
• DLA-DQB1 alleles and bone marrow transplantation experiments in narcoleptic dogs Wagner, J. L., STORB, R., Storer, B., & Mignot, E. (2000). DLA-DQB1 alleles and bone marrow transplantation experiments in narcoleptic dogs. TISSUE ANTIGENS, 56(3), 223-231.
  
• Chronic oral administration of CG-3703, a thyrotropin releasing hormone analog, increases wake and decreases cataplexy in canine narcolepsy Riehl, J., Honda, K., Kwan, M., Hong, J., Mignot, E., & Nishino, S. (2000). Chronic oral administration of CG-3703, a thyrotropin releasing hormone analog, increases wake and decreases cataplexy in canine narcolepsy. NEUROPSYCHOPHARMACOLOGY, 23(1), 34-45.
  
• Narcolepsy: genetic predisposition and neuropharmacological mechanisms Nishino, S., Okura, M., & Mignot, E. (2000). Narcolepsy: genetic predisposition and neuropharmacological mechanisms. SLEEP MEDICINE REVIEWS, 4(1), 57-99.
  
• Clinical and polysomnographic features in DQB1*0602 positive and negative narcolepsy patients: results from the modafinil clinical trial Hong, S. C., Hayduk, R., Lim, J., & Mignot, E. (2000). Clinical and polysomnographic features in DQB1*0602 positive and negative narcolepsy patients: results from the modafinil clinical trial. SLEEP MEDICINE, 1(1), 33-39.
  
• A polymorphism in the human timeless gene is not associated with diurnal preferences in normal adults. Pedrazzoli, M., Ling, L., Finn, L., Kubin, L., Young, T., & Mignot, E. (2000). A polymorphism in the human timeless gene is not associated with diurnal preferences in normal adults. Sleep research online : SRO, 3(2), 73-76.
  
• Perspectives in narcolepsy and hypocretin (orexin) research. Mignot, E. (2000). Perspectives in narcolepsy and hypocretin (orexin) research. Sleep medicine, 1(2), 87-90.
  
• Implication of dopaminergic mechanisms in the wake-promoting effects of amphetamine: A study of D- and L-derivatives in canine narcolepsy Kanbayashi, T., Honda, K., Kodama, T., Mignot, E., & Nishino, S. (2000). Implication of dopaminergic mechanisms in the wake-promoting effects of amphetamine: A study of D- and L-derivatives in canine narcolepsy. NEUROSCIENCE, 99(4), 651-659.
  
• Hypocretin (orexin) deficiency in human narcolepsy Nishino, S., Ripley, B., Overeem, S., Lammers, G. J., & Mignot, E. (2000). Hypocretin (orexin) deficiency in human narcolepsy. LANCET, 355(9197), 39-40.
  
• [Hypocretin (orexin) deficiency in narcolepsy-cataplexy]. Nevsímalová, S., Vanková, J., Sonka, K., Faraco, J., Rogers, W., & Mignot, E. (2000). [Hypocretin (orexin) deficiency in narcolepsy-cataplexy]. Sborník lékar?ský, 101(4), 381-386.
  
• Narcolepsy: genetic predisposition and neuropharmacological mechanisms. REVIEW ARTICLE. Nishino, S., Okura, M., & Mignot, E. (2000). Narcolepsy: genetic predisposition and neuropharmacological mechanisms. REVIEW ARTICLE. Sleep medicine reviews, 4(1), 57-99.
  
• Dopamine D3 agonists into the substantia nigra aggravate cataplexy but do not modify sleep (vol 10, pg 3111, 1999) Honda, K., Riehl, J., Mignot, E., & Nishino, S. (1999). Dopamine D3 agonists into the substantia nigra aggravate cataplexy but do not modify sleep (vol 10, pg 3111, 1999). NEUROREPORT, 10(17), 3717-3724.
  
• Dopamine D-3 agonists into the substratia nigra aggravates cataplexy but does not modify sleep Honda, K., Riehl, J., Mignot, E., & Nishino, S. (1999). Dopamine D-3 agonists into the substratia nigra aggravates cataplexy but does not modify sleep. NEUROREPORT, 10(14), 3111-3118.
  
• A human period gene (HPER1) polymorphism is not associated with diurnal preference in normal adults Katzenberg, D., Young, T., Lin, L., Finn, L., & Mignot, E. (1999). A human period gene (HPER1) polymorphism is not associated with diurnal preference in normal adults. PSYCHIATRIC GENETICS, 9(2), 107-109.
  
• Construction and characterization of an eightfold redundant dog genomic bacterial artificial chromosome library Li, R., Mignot, E., Faraco, J., KADOTANI, H., Cantanese, J., & de Jong, P. J. (1999). Construction and characterization of an eightfold redundant dog genomic bacterial artificial chromosome library. GENOMICS, 58(1), 9-17.
  
• Nocturnal sleep and daytime sleepiness in normal subjects with HLA-DQB1*0602 Mignot, E., Young, T., Lin, L., & Finn, L. (1999). Nocturnal sleep and daytime sleepiness in normal subjects with HLA-DQB1*0602. SLEEP, 22(3), 347-352.
  
• Locus coeruleus neurons: Cessation of activity during cataplexy Wu, M. F., Gulyani, S. A., Yau, E., Mignot, E., Phan, B., & Siegel, J. M. (1999). Locus coeruleus neurons: Cessation of activity during cataplexy. NEUROSCIENCE, 91(4), 1389-1399.
  
• Genetic studies in narcolepsy, a disorder affecting REM sleep Faraco, J., Lin, X., Li, R., Hinton, L., Lin, L., & Mignot, E. (1999). Genetic studies in narcolepsy, a disorder affecting REM sleep. JOURNAL OF HEREDITY, 90(1), 129-132.
  
• Neuronal degeneration in canine narcolepsy Siegel, J. M., Nienhuis, R., Gulyani, S., Ouyang, S., Wu, M. F., & Cornford, M. (1999). Neuronal degeneration in canine narcolepsy. JOURNAL OF NEUROSCIENCE, 19(1), 248-257.
  
• Neuronal activity in the cholinoceptive basal forebrain of freely moving narcoleptic dobermans Nishino, S., Honda, K., Riehl, J., Okura, M., & Mignot, E. (1998). Neuronal activity in the cholinoceptive basal forebrain of freely moving narcoleptic dobermans. NEUROREPORT, 9(16), 3653-3661.
  
• A CLOCK polymorphism associated with human diurnal preference Katzenberg, D., Young, T., Finn, L., Lin, L., King, D. P., & Mignot, E. (1998). A CLOCK polymorphism associated with human diurnal preference. SLEEP, 21(6), 569-576.
  
• Development of cataplexy in genetically narcoleptic Dobermans Riehl, J., Nishino, S., Cederberg, R., Dement, W. C., & Mignot, E. (1998). Development of cataplexy in genetically narcoleptic Dobermans. EXPERIMENTAL NEUROLOGY, 152(2), 292-302.
  
• Microsatellite single nucleotide polymorphisms in the HLA-DQ region Lin, L., Jin, L., Lin, X., Voros, A., Underhill, P., & Mignot, E. (1998). Microsatellite single nucleotide polymorphisms in the HLA-DQ region. TISSUE ANTIGENS, 52(1), 9-18.
  
• Cerebrospinal fluid prostaglandins and corticotropin releasing factor in schizophrenics and controls: relationship to sleep architecture Nishino, S., Mignot, E., Benson, K. L., & Zarcone, V. P. (1998). Cerebrospinal fluid prostaglandins and corticotropin releasing factor in schizophrenics and controls: relationship to sleep architecture. PSYCHIATRY RESEARCH, 78(3), 141-150.
  
• Neuropharmacological characterization of basal forebrain cholinergic stimulated cataplexy in narcoleptic canines Reid, M. S., Nishino, S., Tafti, M., Siegel, J. M., Dement, W. C., & Mignot, E. (1998). Neuropharmacological characterization of basal forebrain cholinergic stimulated cataplexy in narcoleptic canines. EXPERIMENTAL NEUROLOGY, 151(1), 89-104.
  
• Reduction of REM sleep latency associated with HLA-DQB1*0602 in normal adults Mignot, E., Young, T., Lin, L., Finn, L., & Palta, M. (1998). Reduction of REM sleep latency associated with HLA-DQB1*0602 in normal adults. LANCET, 351(9104), 727-727.
  
• Neurobiology of narcolepsy Nishino, S., & Mignot, E. (1998). Neurobiology of narcolepsy. NEUROSCIENTIST, 4(2), 133-143.
  
• Genetic and familial aspects of narcolepsy Mignot, E. (1998). Genetic and familial aspects of narcolepsy. NEUROLOGY, 50(2), S16-S22.
  
• Breeding history of the Stanford colony of narcoleptic dogs Cederberg, R., Nishino, S., Dement, W. C., & Mignot, E. (1998). Breeding history of the Stanford colony of narcoleptic dogs. VETERINARY RECORD, 142(2), 31-36.
  
• HLA-DQB1*0602 homozygosity increases relative risk for narcolepsy but not disease severity in two ethnic groups Pelin, Z., Guilleminault, C., Risch, N., GRUMET, F. C., & Mignot, E. (1998). HLA-DQB1*0602 homozygosity increases relative risk for narcolepsy but not disease severity in two ethnic groups. TISSUE ANTIGENS, 51(1), 96-100.
  
• Characterization of 12 microsatellite loci of the human MHC in a panel of reference cell lines Martin, M. P., Harding, A., Chadwick, R., Kronick, M., Cullen, M., & Carrington, M. (1998). Characterization of 12 microsatellite loci of the human MHC in a panel of reference cell lines. IMMUNOGENETICS, 47(2), 131-138.
  
• The role of genetic factors in the development of narcolepsy and hypersomnia in childhood Nevsimalova, S., & Mignot, E. (1998). The role of genetic factors in the development of narcolepsy and hypersomnia in childhood. 9TH EUROPEAN CONGRESS OF CLINICAL NEUROPHYSIOLOGY, 63-68.
  
• DQ microsatellite association studies in three ethnic groups Lin, L., Jin, L., Kimura, A., Carrington, M., & Mignot, E. (1997). DQ microsatellite association studies in three ethnic groups. TISSUE ANTIGENS, 50(5), 507-520.
  
• HLA class II haplotype and sequence analysis support a role for DQ in narcolepsy Ellis, M. C., Hetisimer, A. H., Ruddy, D. A., Hansen, S. L., Kronmal, G. S., & Mignot, E. (1997). HLA class II haplotype and sequence analysis support a role for DQ in narcolepsy. IMMUNOGENETICS, 46(5), 410-417.
  
• Effects of thyrotropin-releasing hormone and its analogs on daytime sleepiness and cataplexy in canine narcolepsy Nishino, S., Arrigoni, J., Shelton, J., Kanbayashi, T., Dement, W. C., & Mignot, E. (1997). Effects of thyrotropin-releasing hormone and its analogs on daytime sleepiness and cataplexy in canine narcolepsy. JOURNAL OF NEUROSCIENCE, 17(16), 6401-6408.
  
• Genetics of narcolepsy and other sleep disorders Mignot, E. (1997). Genetics of narcolepsy and other sleep disorders. AMERICAN JOURNAL OF HUMAN GENETICS, 60(6), 1289-1302.
  
• HLA DR15 (DR2) and DQB1*0602 typing studies in 188 narcoleptic patients with cataplexy Rogers, A. E., Meehan, J., Guilleminault, C., GRUMET, F. C., & Mignot, E. (1997). HLA DR15 (DR2) and DQB1*0602 typing studies in 188 narcoleptic patients with cataplexy. NEUROLOGY, 48(6), 1550-1556.
  
• Extensive HLA class II studies in 58 non-DRB1*15 (DR2) narcoleptic patients with cataplexy Mignot, E., Kimura, A., Lattermann, A., Lin, X., Yasunaga, S., & Underhill, P. (1997). Extensive HLA class II studies in 58 non-DRB1*15 (DR2) narcoleptic patients with cataplexy. TISSUE ANTIGENS, 49(4), 329-341.
  
• Mesopontine organization of cholinergic and catecholaminergic cell groups in the normal and narcoleptic dog Tafti, M., Nishino, S., Liao, W., Dement, W. C., & Mignot, E. (1997). Mesopontine organization of cholinergic and catecholaminergic cell groups in the normal and narcoleptic dog. JOURNAL OF COMPARATIVE NEUROLOGY, 379(2), 185-197.
  
• HLA DQB1*0602 is associated with cataplexy in 509 narcoleptic patients Mignot, E., Hayduk, R., Black, J., GRUMET, F. C., & Guilleminault, C. (1997). HLA DQB1*0602 is associated with cataplexy in 509 narcoleptic patients. SLEEP, 20(11), 1012-1020.
  
• The natural history of a microsatellite located in the HLA DQ region Mignot, E., Macaubas, C., Jin, L., Hallmayer, J., Kimura, A., & GRUMET, F. C. (1997). The natural history of a microsatellite located in the HLA DQ region. HLA - GENETIC DIVERSITY OF HLA FUNCTIONAL AND MEDICAL IMPLICATION, PROCEEDINGS OF THE TWELFTH INTERNATIONAL HISTOCOMPATIBILITY WORKSHOP AND CONFERENCE (12TH IHWC), VOL II: CONFERENCE, 121-124.
  
• HLA class II studies in non DRB1*1501 patients with narcolepsy-cataplexy Mignot, E., Kimura, A., Lattermann, A., GRUMET, F. C., Mayer, G., & Mueller-Eckhardt, G. (1997). HLA class II studies in non DRB1*1501 patients with narcolepsy-cataplexy. HLA - GENETIC DIVERSITY OF HLA FUNCTIONAL AND MEDICAL IMPLICATION, PROCEEDINGS OF THE TWELFTH INTERNATIONAL HISTOCOMPATIBILITY WORKSHOP AND CONFERENCE (12TH IHWC), VOL I: WORKSHOP, 436-441.
  
• Familial aspects of narcolepsy-cataplexy in the Czech Republic Nevsimalova, S., Mignot, E., Sonka, K., & Arrigoni, J. L. (1997). Familial aspects of narcolepsy-cataplexy in the Czech Republic. SLEEP, 20(11), 1021-1026.
  
• Mutation rate varies among alleles at a microsatellite locus: Phylogenetic evidence Jin, L., Macaubas, C., Hallmayer, J., Kimura, A., & Mignot, E. (1996). Mutation rate varies among alleles at a microsatellite locus: Phylogenetic evidence. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 93(26), 15285-15288.
  
• Local administration of dopaminergic drugs into the ventral tegmental area modulates cataplexy in the narcoleptic canine Reid, M. S., Tafti, M., Nishino, S., Sampathkumaran, R., Siegel, J. M., & Mignot, E. (1996). Local administration of dopaminergic drugs into the ventral tegmental area modulates cataplexy in the narcoleptic canine. BRAIN RESEARCH, 733(1), 83-100.
  
• Thalidomide, a hypnotic with immune modulating properties, increases cataplexy in canine narcolepsy Kanbayashi, T., Nishino, S., Tafti, M., Hishikawa, Y., Dement, W. C., & Mignot, E. (1996). Thalidomide, a hypnotic with immune modulating properties, increases cataplexy in canine narcolepsy. NEUROREPORT, 7(12), 1881-1886.
  
• Major histocompatibility class II molecules in the CNS: Increased microglial expression at the onset of narcolepsy in a canine model Tafti, M., Nishino, S., Aldrich, M. S., Liao, W. N., Dement, W. C., & Mignot, E. (1996). Major histocompatibility class II molecules in the CNS: Increased microglial expression at the onset of narcolepsy in a canine model. JOURNAL OF NEUROSCIENCE, 16(15), 4588-4595.
  
• IgH (mu-switch and gamma-1) region restriction fragment length polymorphism in human narcolepsy Singh, S. M., George, C. Fp., OTT, R. N., Rattazzi, C., Guilleminault, C., & Mignot, E. (1996). IgH (mu-switch and gamma-1) region restriction fragment length polymorphism in human narcolepsy. JOURNAL OF CLINICAL IMMUNOLOGY, 16(4), 208-215.
  
• The natural history of a microsatellite located in the HLA DQ region Mignot, E., Macaubas, C., Jin, L., Hallmayer, J., Kimura, A., & GRUMET, F. C. (1996). The natural history of a microsatellite located in the HLA DQ region. HUMAN IMMUNOLOGY, 47(1-2), O09-O09.
  
• Thalidomide, immune modulation and narcolepsy Kanbayashi, T., Nishino, S., Tafti, M., Hishikawa, Y., Dement, W. C., & Mignot, E. (1996). Thalidomide, immune modulation and narcolepsy. SLEEP, 19(2), 116-116.
  
• Some genetic aspects of narcolepsy Nevsimalova, S., Mignot, E., Sonka, K., & Arrigoni, J. L. (1996). Some genetic aspects of narcolepsy. CESKA A SLOVENSKA NEUROLOGIE A NEUROCHIRURGIE, 59(4), 210-215.
  
• Comparative effects of modafinil and amphetamine on daytime sleepiness and cataplexy of narcoleptic dogs Shelton, J., Nishino, S., Vaught, J., Dement, W. C., & Mignot, E. (1995). Comparative effects of modafinil and amphetamine on daytime sleepiness and cataplexy of narcoleptic dogs. SLEEP, 18(10), 817-826.
  
• DQCAR MICROSATELLITE POLYMORPHISMS IN 3 SELECTED HLA CLASS II-ASSOCIATED DISEASES Mignot, E., Kimura, A., Abbal, M., Thorsby, E., Lin, X., & GRUMET, F. C. (1995). DQCAR MICROSATELLITE POLYMORPHISMS IN 3 SELECTED HLA CLASS II-ASSOCIATED DISEASES. TISSUE ANTIGENS, 46(4), 299-304.
  
• TRACKING THE EVOLUTION OF A MICROSATELLITE LOCUS LOCATED IN THE HLA-DQA1/DQB1 CLASS-II REGION Macaubas, C., Jin, L., Hallmayer, J., Kimura, A., & Mignot, E. (1995). TRACKING THE EVOLUTION OF A MICROSATELLITE LOCUS LOCATED IN THE HLA-DQA1/DQB1 CLASS-II REGION. AMERICAN JOURNAL OF HUMAN GENETICS, 57(4), 953-953.
  
• MUSCLE ATONIA IS TRIGGERED BY CHOLINERGIC STIMULATION OF THE BASAL FOREBRAIN - IMPLICATION FOR THE PATHOPHYSIOLOGY OF CANINE NARCOLEPSY Nishino, S., Tafti, M., Reid, M. S., Shelton, J., Siegel, J. M., & Mignot, E. (1995). MUSCLE ATONIA IS TRIGGERED BY CHOLINERGIC STIMULATION OF THE BASAL FOREBRAIN - IMPLICATION FOR THE PATHOPHYSIOLOGY OF CANINE NARCOLEPSY. JOURNAL OF NEUROSCIENCE, 15(7), 4806-4814.
  
• EXTENSIVE POLYMORPHISM OF A (CA)(N) MICROSATELLITE LOCATED IN THE HLA-DQA1/DQB1 CLASS-II REGION Macaubas, C., Hallmayer, J., Kalil, J., Kimura, A., Yasunaga, S., & Mignot, E. (1995). EXTENSIVE POLYMORPHISM OF A (CA)(N) MICROSATELLITE LOCATED IN THE HLA-DQA1/DQB1 CLASS-II REGION. HUMAN IMMUNOLOGY, 42(3), 209-220.
  
• EFFECT OF 5-HT1A RECEPTOR AGONISTS AND ANTAGONISTS ON CANINE CATAPLEXY Nishino, S., Shelton, J., RENAUD, A., Dement, W. C., & Mignot, E. (1995). EFFECT OF 5-HT1A RECEPTOR AGONISTS AND ANTAGONISTS ON CANINE CATAPLEXY. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 272(3), 1170-1175.
  
• A NEW DRB1(ASTERISK)1202 ALLELE (DRB1(ASTERISK)12022) FOUND IN ASSOCIATION WITH DQA1(ASTERISK)0102 AND DQB1(ASTERISK)0602 IN 2 BLACK NARCOLEPTIC SUBJECTS Behar, E., Lin, X. Y., GRUMET, F. C., & Mignot, E. (1995). A NEW DRB1(ASTERISK)1202 ALLELE (DRB1(ASTERISK)12022) FOUND IN ASSOCIATION WITH DQA1(ASTERISK)0102 AND DQB1(ASTERISK)0602 IN 2 BLACK NARCOLEPTIC SUBJECTS. IMMUNOGENETICS, 41(1), 52-52.
  
• NARCOLEPSY AND IMMUNITY Mignot, E., Tafti, M., Dement, W. C., & GRUMET, F. C. (1995). NARCOLEPSY AND IMMUNITY. ADVANCES IN NEUROIMMUNOLOGY, 5(1), 23-37.
  
• CONTROVERSIES IN THE DIAGNOSIS OF NARCOLEPSY Guilleminault, C., Mignot, E., & Partinen, M. (1994). CONTROVERSIES IN THE DIAGNOSIS OF NARCOLEPSY. SLEEP, 17(8), S1-S6.
  
• NEUROPHARMACOLOGY AND NEUROCHEMISTRY OF CANINE NARCOLEPSY Nishino, S., Reid, M. S., Dement, W. C., & Mignot, E. (1994). NEUROPHARMACOLOGY AND NEUROCHEMISTRY OF CANINE NARCOLEPSY. SLEEP, 17(8), S84-S92.
  
• AN IMMUNOGLOBULIN SWITCHLIKE SEQUENCE IS LINKED WITH CANINE NARCOLEPSY Mignot, E., Bell, R. A., Rattazzi, C., LOVETT, M., GRUMET, F. C., & Dement, W. C. (1994). AN IMMUNOGLOBULIN SWITCHLIKE SEQUENCE IS LINKED WITH CANINE NARCOLEPSY. SLEEP, 17(8), S68-S76.
  
• DQB1-ASTERISK-0602 AND DQA1-ASTERISK-0102 (DQ1) ARE BETTER MARKERS THAN DR2 FOR NARCOLEPSY IN CAUCASIAN AND BLACK-AMERICANS Mignot, E., Lin, X., Arrigoni, J., Macaubas, C., Olive, F., & GRUMET, F. C. (1994). DQB1-ASTERISK-0602 AND DQA1-ASTERISK-0102 (DQ1) ARE BETTER MARKERS THAN DR2 FOR NARCOLEPSY IN CAUCASIAN AND BLACK-AMERICANS. SLEEP, 17(8), S60-S67.
  
• CHOLINERGIC REGULATION OF CATAPLEXY IN CANINE NARCOLEPSY IN THE PONTINE RETICULAR-FORMATION IS MEDIATED BY M2 MUSCARINIC RECEPTORS Reid, M. S., Tafti, M., Nishino, S., Siegel, J. M., Dement, W. C., & Mignot, E. (1994). CHOLINERGIC REGULATION OF CATAPLEXY IN CANINE NARCOLEPSY IN THE PONTINE RETICULAR-FORMATION IS MEDIATED BY M2 MUSCARINIC RECEPTORS. SLEEP, 17(5), 424-435.
  
• MODAFINIL BINDS TO THE DOPAMINE UPTAKE CARRIER SITE WITH LOW-AFFINITY Mignot, E., Nishino, S., Guilleminault, C., & Dement, W. C. (1994). MODAFINIL BINDS TO THE DOPAMINE UPTAKE CARRIER SITE WITH LOW-AFFINITY. SLEEP, 17(5), 436-437.
  
• CHOLINERGIC MECHANISMS IN CANINE NARCOLEPSY .1. MODULATION OF CATAPLEXY VIA LOCAL-DRUG ADMINISTRATION INTO THE PONTINE RETICULAR-FORMATION Reid, M. S., Tafti, M., GEARY, J. N., Nishino, S., Siegel, J. M., & Mignot, E. (1994). CHOLINERGIC MECHANISMS IN CANINE NARCOLEPSY .1. MODULATION OF CATAPLEXY VIA LOCAL-DRUG ADMINISTRATION INTO THE PONTINE RETICULAR-FORMATION. NEUROSCIENCE, 59(3), 511-522.
  
• STABILITY OF CATAPLEXY OVER SEVERAL MONTHS - INFORMATION FOR THE DESIGN OF THERAPEUTIC TRIALS Gelb, M., Guilleminault, C., Kraemer, H., Lin, S., Moon, S., & Mignot, E. (1994). STABILITY OF CATAPLEXY OVER SEVERAL MONTHS - INFORMATION FOR THE DESIGN OF THERAPEUTIC TRIALS. SLEEP, 17(3), 265-273.
  
• CHOLINERGIC MECHANISMS IN CANINE NARCOLEPSY .2. ACETYLCHOLINE-RELEASE IN THE PONTINE RETICULAR-FORMATION IS ENHANCED DURING CATAPLEXY Reid, M. S., Siegel, J. M., Dement, W. C., & Mignot, E. (1994). CHOLINERGIC MECHANISMS IN CANINE NARCOLEPSY .2. ACETYLCHOLINE-RELEASE IN THE PONTINE RETICULAR-FORMATION IS ENHANCED DURING CATAPLEXY. NEUROSCIENCE, 59(3), 523-530.
  
• DESMETHYL METABOLITES OF SEROTONERGIC UPTAKE INHIBITORS ARE MORE POTENT FOR SUPPRESSING CANINE CATAPLEXY THAN THEIR PARENT COMPOUNDS Nishino, S., Arrigoni, J., Shelton, J., Dement, W. C., & Mignot, E. (1993). DESMETHYL METABOLITES OF SEROTONERGIC UPTAKE INHIBITORS ARE MORE POTENT FOR SUPPRESSING CANINE CATAPLEXY THAN THEIR PARENT COMPOUNDS. SLEEP, 16(8), 706-712.
  
• FURTHER CHARACTERIZATION OF THE ALPHA-1 RECEPTOR SUBTYPE INVOLVED IN THE CONTROL OF CATAPLEXY IN CANINE NARCOLEPSY Nishino, S., Fruhstorfer, B., Arrigoni, J., Guilleminault, C., Dement, W. C., & Mignot, E. (1993). FURTHER CHARACTERIZATION OF THE ALPHA-1 RECEPTOR SUBTYPE INVOLVED IN THE CONTROL OF CATAPLEXY IN CANINE NARCOLEPSY. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 264(3), 1079-1084.
  
• PHARMACOLOGICAL CONTROL OF NARCOLEPSY AND REM-SLEEP Mignot, E., & Guilleminault, C. (1993). PHARMACOLOGICAL CONTROL OF NARCOLEPSY AND REM-SLEEP. ENDOCRINE AND NUTRITIONAL CONTROL OF BASIC BIOLOGICAL FUNCTIONS, 7, 307-314.
  
• DQB1-0602 (DQW1) IS NOT PRESENT IN MOST NONDR2 CAUCASIAN NARCOLEPTICS Mignot, E., Lin, X., Kalil, J., George, C., Singh, S., & GRUMET, F. C. (1992). DQB1-0602 (DQW1) IS NOT PRESENT IN MOST NONDR2 CAUCASIAN NARCOLEPTICS. SLEEP, 15(5), 415-422.
  
• MONOAMINERGIC UPTAKE IN SYNAPTOSOMES PREPARED FROM FROZEN BRAIN-TISSUE SAMPLES OF NORMAL AND NARCOLEPTIC CANINES VALTIER, D., Dement, W. C., & Mignot, E. (1992). MONOAMINERGIC UPTAKE IN SYNAPTOSOMES PREPARED FROM FROZEN BRAIN-TISSUE SAMPLES OF NORMAL AND NARCOLEPTIC CANINES. BRAIN RESEARCH, 588(1), 115-119.
  
• ACTIVITY OF MEDIAL MESOPONTINE UNITS DURING CATAPLEXY AND SLEEP-WAKING STATES IN THE NARCOLEPTIC DOG Siegel, J. M., Nienhuis, R., Fahringer, H. M., Chiu, C., Dement, W. C., & Lufkin, R. (1992). ACTIVITY OF MEDIAL MESOPONTINE UNITS DURING CATAPLEXY AND SLEEP-WAKING STATES IN THE NARCOLEPTIC DOG. JOURNAL OF NEUROSCIENCE, 12(5), 1640-1646.
  
• STRATEGIES FOR THE DEVELOPMENT OF NEW TREATMENTS IN SLEEP DISORDER MEDICINE Mignot, E., Edgar, D. M., Miller, J. D., Prosser, R. A., VANGELDER, R. N., & Dement, W. C. (1992). STRATEGIES FOR THE DEVELOPMENT OF NEW TREATMENTS IN SLEEP DISORDER MEDICINE. TARGET RECEPTORS FOR ANXIOLYTICS AND HYPNOTICS : FROM MOLECULAR PHARMACOLOGY TO THERAPEUTICS, 3, 129-150.
  
• DOPAMINE-D2 MECHANISMS IN CANINE NARCOLEPSY Nishino, S., Arrigoni, J., VALTIER, D., Miller, J. D., Guilleminault, C., & Mignot, E. (1991). DOPAMINE-D2 MECHANISMS IN CANINE NARCOLEPSY. JOURNAL OF NEUROSCIENCE, 11(9), 2666-2671.
  
• NEURONAL-ACTIVITY IN NARCOLEPSY - IDENTIFICATION OF CATAPLEXY-RELATED CELLS IN THE MEDIAL MEDULLA Siegel, J. M., Nienhuis, R., Fahringer, H. M., Paul, R., Shiromani, P., & Chiu, C. (1991). NEURONAL-ACTIVITY IN NARCOLEPSY - IDENTIFICATION OF CATAPLEXY-RELATED CELLS IN THE MEDIAL MEDULLA. SCIENCE, 252(5010), 1315-1318.
  
• GENETIC-LINKAGE OF AUTOSOMAL RECESSIVE CANINE NARCOLEPSY WITH A MU-IMMUNOGLOBULIN HEAVY-CHAIN SWITCH-LIKE SEGMENT Mignot, E., Wang, C., Rattazzi, C., Gaiser, C., LOVETT, M., & GRUMET, F. C. (1991). GENETIC-LINKAGE OF AUTOSOMAL RECESSIVE CANINE NARCOLEPSY WITH A MU-IMMUNOGLOBULIN HEAVY-CHAIN SWITCH-LIKE SEGMENT. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 88(8), 3475-3478.
  
• RADIOLIGAND BINDING TO ADENOSINE RECEPTORS AND ADENOSINE UPTAKE SITES IN DIFFERENT BRAIN-REGIONS OF NORMAL AND NARCOLEPTIC DOGS Hawkins, M., OCONNOR, S., Radulovacki, M., Bowersox, S., Mignot, E., & Dement, W. (1991). RADIOLIGAND BINDING TO ADENOSINE RECEPTORS AND ADENOSINE UPTAKE SITES IN DIFFERENT BRAIN-REGIONS OF NORMAL AND NARCOLEPTIC DOGS. PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR, 38(1), 1-6.
  
• EFFECTS OF CENTRAL ALPHA-2 ADRENERGIC COMPOUNDS ON CANINE NARCOLEPSY, A DISORDER OF RAPID EYE-MOVEMENT SLEEP Nishino, S., Haak, L., Shepherd, H., Guilleminault, C., Sakai, T., & Mignot, E. (1990). EFFECTS OF CENTRAL ALPHA-2 ADRENERGIC COMPOUNDS ON CANINE NARCOLEPSY, A DISORDER OF RAPID EYE-MOVEMENT SLEEP. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 253(3), 1145-1152.
  
• RECEPTOLOGY IN NARCOLEPSY Mignot, E., & Guilleminault, C. (1990). RECEPTOLOGY IN NARCOLEPSY. NEUROLOGY IN EUROPE 1, 521-530.
  
• EFFECTS OF INTRAVENOUS ADMINISTRATION OF PROSTAGLANDINS ON CANINE NARCOLEPSY Nishino, S., Mignot, E., Fruhstorfer, B., Kilduff, T. S., Ueno, R., & Dement, W. C. (1990). EFFECTS OF INTRAVENOUS ADMINISTRATION OF PROSTAGLANDINS ON CANINE NARCOLEPSY. ENDOGENOUS SLEEP FACTORS, 77-83.
  
• NORADRENERGIC AND CHOLINERGIC CONTROL OF CATAPLEXY - PHARMACOLOGICAL EVIDENCE Mignot, E., Nishino, S., Guilleminault, C., & Dement, W. C. (1990). NORADRENERGIC AND CHOLINERGIC CONTROL OF CATAPLEXY - PHARMACOLOGICAL EVIDENCE. ENDOGENOUS SLEEP FACTORS, 203-215.
  
• FAMILIAL PATTERNS OF NARCOLEPSY Guilleminault, C., Mignot, E., & GRUMET, F. C. (1989). FAMILIAL PATTERNS OF NARCOLEPSY. LANCET, 2(8676), 1376-1379.
  
• EVIDENCE FOR MULTIPLE [H-3] PRAZOSIN BINDING-SITES IN CANINE BRAIN MEMBRANES Mignot, E., Bowersox, S. S., Maddaluno, J., Dement, W., & CIARANELLO, R. (1989). EVIDENCE FOR MULTIPLE [H-3] PRAZOSIN BINDING-SITES IN CANINE BRAIN MEMBRANES. BRAIN RESEARCH, 486(1), 56-66.
  
• PROSTAGLANDIN-E2 AND ITS METHYL-ESTER REDUCE CATAPLEXY IN CANINE NARCOLEPSY Nishino, S., Mignot, E., Fruhstorfer, B., Dement, W. C., & Hayaishi, O. (1989). PROSTAGLANDIN-E2 AND ITS METHYL-ESTER REDUCE CATAPLEXY IN CANINE NARCOLEPSY. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 86(7), 2483-2487.
  
• ROLE OF CENTRAL ALPHA-1 ADRENOCEPTORS IN CANINE NARCOLEPSY Mignot, E., Guilleminault, C., Bowersox, S., Rappaport, A., & Dement, W. C. (1988). ROLE OF CENTRAL ALPHA-1 ADRENOCEPTORS IN CANINE NARCOLEPSY. JOURNAL OF CLINICAL INVESTIGATION, 82(3), 885-894.