Format

Send to

Choose Destination
Clin Cancer Res. 2015 Aug 1;21(15):3393-401. doi: 10.1158/1078-0432.CCR-14-1191. Epub 2015 May 19.

Emerging Treatment Paradigms in Radiation Oncology.

Author information

1
Department of Radiation Oncology, Stanford University, Stanford, California. qle@stanford.edu.
2
Global Station for Quantum Medical Science and Engineering, Global Institution for Collaborative Research and Education, Hokkaido University, Sapporo, Japan.
3
Department of Radiation Oncology, Stanford University, Stanford, California.

Abstract

Rapid advancements in radiotherapy and molecularly targeted therapies have resulted in the development of potential paradigm-shifting use of radiotherapy in the treatment of cancer. In this review, we discuss some of the most promising therapeutic approaches in the field of radiation oncology. These strategies include the use of highly targeted stereotactic radiotherapy and particle therapy as well as combining radiotherapy with agents that modulate the DNA damage response, augment the immune response, or protect normal tissues.

PMID:
25991820
PMCID:
PMC4526434
DOI:
10.1158/1078-0432.CCR-14-1191
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for HighWire Icon for PubMed Central
Loading ...
Support Center