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Epilepsia. 2018 Jun;59(6):1132-1137. doi: 10.1111/epi.14197. Epub 2018 May 17.

Cognitive safety of intracranial electrodes for epilepsy.

Author information

1
Department of Neurology & Neurological Sciences, Stanford University, Palo Alto, CA, USA.
2
Department of Neurosurgery, Stanford University, Palo Alto, CA, USA.
3
Department of Neurology, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA.

Abstract

Two recent articles in Epilepsia have raised concerns about adverse cognitive effects associated with intracranial electrode implantation. However, both studies have important limitations, and their results contrast with studies that report no adverse cognitive effects of intracranial electrodes for diagnosis or neurostimulation in epilepsy. Furthermore, no data are provided on the relative safety of depth electrodes implanted along the longitudinal axis of the hippocampus vs other electrode locations or types of electrodes. Instituting changes in the use of depth electrodes based solely on these 2 studies is not clinically indicated. Further research is needed.

KEYWORDS:

epilepsy surgery; intracranial electrodes; memory; neuropsychology

PMID:
29771452
DOI:
10.1111/epi.14197
[Indexed for MEDLINE]

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