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Skip Navigation LinksHome > Funding > NIH Categorical Spending

RCDC

Estimates of Funding for Various Research, Condition, and Disease Categories (RCDC)

Click here to view information on Disease Burden
Table Published: February 5, 2015

The table below displays the annual support level for various research, condition, and disease categories based on grants, contracts, and other funding mechanisms used across the National Institutes of Health (NIH).

At the request of Congress, the NIH embarked on a process to provide better consistency and transparency in the reporting of its funded research. This new process, implemented in 2008 through the Research, Condition, and Disease Categorization (RCDC) system, uses sophisticated text data mining (categorizing and clustering using words and multiword phrases) in conjunction with NIH-wide definitions used to match projects to categories. RCDC use of data mining improves consistency and eliminates the wide variability in defining the research categories reported. The definitions are a list of terms and concepts selected by NIH scientific experts to define a research category. The research category levels represent the NIH’s best estimates based on the category definitions. For a federal source of case-by-case burden data on a broad variety of diseases, conditions, and populations, please see the Centers for Disease Control and Prevention (CDC) FastStats site.

The NIH does not expressly budget by category. The annual estimates reflect amounts that change as a result of science, actual research projects funded, and the NIH budget. The research categories are not mutually exclusive. Individual research projects can be included in multiple categories so amounts depicted within each column of this table do not add up to 100 percent of NIH-funded research.

The table shows historical data for FY 2011 through FY 2014. The FY 2015-2016 estimates are based on RCDC actual data.

Total Number of Research/Disease Areas: 244

Click here for instructions on how to use the data table below.

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Research/Disease Areas
(Dollars in millions and rounded)		FY 2011ActualFY 2012ActualFY 2013ActualFY 2014ActualFY 2015EstimatedFY 2016Estimated
Acute Respiratory Distress Syndrome $96 $98 $95 $85 $86 $88
Adolescent Sexual Activity $69 $76 $70 $68 $69 $70
Agent Orange & Dioxin $8 $8 $10 $8 $8 $8
Aging $2,572 $2,593 $2,429 $2,556 $2,548 $2,585
Alcoholism $452 $455 $437 $475 $476 $490
Allergic Rhinitis (Hay Fever) $7 $7 $9 $6 $6 $6
ALS $44 $44 $39 $48 $48 $50
Alzheimer's Disease $448 $503 $504 $562 $586 $638
American Indians / Alaska Natives $136 $170 $160 $166 $167 $172
Anorexia $11 $14 $11 $11 $11 $11
Anthrax $87 $84 $70 $67 $67 $67
Antimicrobial Resistance $369 $377 $325 $277 $361 $461
Aphasia $21 $24 $24 $24 $24 $25
Arctic $28 $23 $19 $16 $16 $16
Arthritis $231 $258 $231 $239 $240 $245
Assistive Technology $250 $237 $220 $228 $229 $234
Asthma $221 $229 $207 $241 $242 $246
Ataxia Telangiectasia $13 $11 $11 $8 $8 $8
Atherosclerosis $475 $477 $374 $375 $376 $385
Attention Deficit Disorder (ADD) $55 $60 $49 $44 $45 $46
Autism $169 $192 $186 $188 $189 $193
Autoimmune Disease $869 $867 $821 $822 $832 $845
Basic Behavioral and Social Science $1,173 $1,215 $1,172 $1,234 $1,242 $1,272
Batten Disease $4 $4 $5 $5 $5 $5
Behavioral and Social Science $3,573 $3,682 $3,535 $3,688 $3,711 $3,797
Biodefense 1/ $1,803 $1,791 $1,692 $1,746 $1,745 $1,848
Bioengineering $3,303 $3,498 $3,234 $3,329 $3,353 $3,432
Biotechnology $5,823 $6,089 $5,698 $5,889 $5,925 $6,046
Brain Cancer $280 $281 $280 $289 $290 $299
Brain Disorders $3,864 $3,968 $3,708 $3,894 $3,920 $4,014
Breast Cancer $715 $800 $657 $682 $685 $704
Burden of Illness $40 $84 $72 $73 $74 $76
Cancer $5,448 $5,621 $5,274 $5,392 $5,414 $5,568
Cardiovascular $2,049 $2,040 $1,964 $1,950 $1,957 $2,004
Cerebral Palsy $23 $42 $18 $21 $21 $21
Cervical Cancer $119 $112 $98 $116 $116 $119
Charcot-Marie-Tooth Disease $13 $13 $11 $14 $14 $14
Child Abuse and Neglect Research $30 $32 $30 $30 $30 $31
Childhood Leukemia $59 $77 $67 $105 $105 $108
Chronic Fatigue Syndrome (ME/CFS) $6 $5 $5 $5 $5 $6
Chronic Liver Disease and Cirrhosis $303 $288 $282 $293 $294 $300
Chronic Obstructive Pulmonary Disease $108 $101 $102 $107 $108 $110
Climate Change $6 $8 $8 $6 $6 $6
Climate-Related Exposures and Conditions 10/ $155 $157 $137 $131 $131 $134
Clinical Research $10,503 $10,951 $10,604 $11,087 $11,132 $11,376
Clinical Trials $3,093 $3,208 $3,155 $3,221 $3,233 $3,298
Colo-Rectal Cancer $313 $302 $281 $271 $272 $280
Comparative Effectiveness Research $517 $597 $559 $610 $612 $627
Complementary and Alternative Medicine $442 $493 $380 $367 $369 $378
Conditions Affecting the Embryonic and Fetal Periods 11/ $157 $165 $151 $175 $176 $180
Contraception/Reproduction $415 $448 $408 $394 $397 $405
Cooley's Anemia $20 $20 $15 $18 $18 $18
Cost Effectiveness Research $71 $78 $82 $70 $70 $71
Crohn's Disease $67 $76 $61 $65 $66 $67
Cystic Fibrosis $79 $86 $78 $77 $77 $79
Dementia $0 $0 $650 $704 $731 $789
Dental/Oral and Craniofacial Disease $501 $516 $480 $483 $484 $495
Depression $426 $429 $415 $396 $397 $404
Diabetes 2/ $1,076 $1,061 $1,007 $1,011 $1,020 $1,039
Diagnostic Radiology $1,071 $1,090 $1,079 $1,078 $1,085 $1,110
Diethylstilbestrol (DES) $3 $3 $1 $1 $1 $1
Digestive Diseases $1,698 $1,719 $1,575 $1,607 $1,613 $1,646
Digestive Diseases - (Gallbladder) $4 $11 $10 $9 $9 $10
Digestive Diseases - (Peptic Ulcer) $18 $20 $19 $15 $15 $15
Down Syndrome $20 $20 $18 $18 $18 $19
Drug Abuse (NIDA Only) 3/ $1,051 $1,052 $993 $1,018 $1,016 $1,047
Duchenne/ Becker Muscular Dystrophy $32 $34 $33 $32 $32 $33
Dystonia $13 $14 $13 $12 $12 $13
Eating Disorders 4/ $27 $34 $31 $30 $30 $30
Emerging Infectious Diseases $2,190 $2,153 $1,804 $1,930 $1,933 $1,942
Emphysema $22 $20 $24 $27 $27 $27
Endometriosis $14 $9 $7 $7 $7 $7
Epilepsy $152 $156 $129 $154 $156 $161
Estrogen $227 $221 $218 $203 $204 $209
Eye Disease And Disorders Of Vision $831 $841 $774 $824 $826 $849
Facioscapulohumeral Muscular Dystrophy $6 $5 $5 $7 $7 $7
Fetal Alcohol Syndrome $36 $32 $33 $34 $34 $35
Fibroid Tumors (Uterine) $12 $14 $10 $9 $9 $9
Fibromyalgia $11 $13 $11 $10 $10 $11
Food Allergies $33 $31 $36 $35 $35 $35
Food Safety $287 $257 $229 $232 $232 $233
Fragile X Syndrome $29 $27 $30 $36 $37 $37
Frontotemporal Dementia (FTD) $23 $26 $32 $37 $37 $38
Gene Therapy $248 $256 $226 $253 $255 $260
Gene Therapy Clinical Trials $14 $15 $15 $26 $26 $27
Genetic Testing $270 $255 $272 $231 $231 $237
Genetics $7,223 $7,632 $7,144 $7,324 $7,364 $7,535
Global Warming Climate Change $5 $6 $6 $4 $4 $4
Headaches $21 $24 $25 $24 $24 $25
Health Disparities 5/ $2,718 $2,740 $2,722 $2,734 $2,736 $2,750
Health Services $1,172 $1,317 $1,262 $1,342 $1,347 $1,376
Heart Disease $1,236 $1,278 $1,230 $1,224 $1,228 $1,258
Heart Disease - Coronary Heart Disease $437 $468 $404 $421 $423 $433
Hematology $1,006 $1,091 $1,020 $1,189 $1,194 $1,225
Hepatitis $208 $210 $195 $251 $252 $256
Hepatitis - A $4 $2 $2 $3 $3 $3
Hepatitis - B $58 $51 $48 $48 $48 $49
Hepatitis - C $114 $112 $101 $111 $111 $112
HIV/AIDS 6/ $3,059 $3,074 $2,898 $2,978 $3,000 $3,100
Hodgkin's Disease $20 $21 $13 $14 $14 $14
Homelessness $9 $10 $11 $14 $14 $15
Homicide and Legal Interventions $1 $1 $0 $0 - -
HPV and/or Cervical Cancer Vaccines $24 $26 $25 $38 $38 $39
Human Fetal Tissue 7/ $66 $71 $67 $76 $76 $77
Human Genome $1,907 $2,271 $2,473 $2,701 $2,717 $2,785
Huntington's Disease $56 $65 $55 $50 $51 $53
Hydrocephalus + $7 $6 $5 $5 $6
Hyperbaric Oxygen $2 $2 $1 $2 $2 $2
Hypertension $240 $215 $222 $216 $217 $222
Immunization $1,756 $1,733 $1,656 $1,607 $1,610 $1,621
Infant Mortality/ (LBW) $286 $287 $253 $268 $269 $275
Infectious Diseases $3,883 $3,867 $4,887 $5,002 $5,015 $5,181
Infertility $74 $74 $78 $76 $77 $79
Inflammatory Bowel Disease $113 $121 $114 $125 $126 $128
Influenza $272 $251 $304 $262 $263 $284
Injury - Childhood Injuries $33 $37 $37 $35 $35 $36
Injury - Trauma - (Head and Spine) $166 $171 $183 $216 $218 $225
Injury - Traumatic brain injury $81 $79 $88 $87 $88 $91
Injury - Unintentional Childhood Injury $20 $22 $20 $22 $22 $22
Injury (total) Accidents/Adverse Effects $356 $366 $367 $404 $407 $418
Intellectual and Developmental Disabilities (IDD) 11/ $333 $355 $343 $356 $358 $365
Interstitial Cystitis $13 $10 $10 $9 $10 $10
Kidney Disease $557 $556 $551 $549 $551 $563
Lead Poisoning $10 $8 $8 $7 $7 $7
Lewy Body Dementia + + + $15 $15 $15
Liver Cancer $74 $73 $71 $74 $74 $76
Liver Disease $623 $632 $594 $605 $607 $619
Lung $1,278 $1,286 $1,230 $1,329 $1,335 $1,363
Lung Cancer $221 $233 $208 $254 $255 $263
Lupus $106 $108 $92 $99 $99 $100
Lyme Disease $28 $25 $20 $23 $23 $23
Lymphoma $199 $213 $233 $251 $252 $259
Macular Degeneration $105 $101 $98 $82 $82 $83
Malaria $145 $152 $147 $169 $169 $173
Malaria Vaccine $39 $40 $34 $36 $36 $36
Mental Health $2,275 $2,287 $2,174 $2,213 $2,234 $2,299
Methamphetamine $70 $69 $68 $63 $63 $65
Migraines $16 $18 $19 $20 $20 $21
Mind and Body $533 $533 $210 $211 $212 $216
Minority Health 5/ $2,504 $2,487 $2,428 $2,514 $2,515 $2,528
Mucopolysaccharidoses (MPS) $10 $10 $8 $6 $7 $7
Multiple Sclerosis $122 $115 $112 $102 $103 $105
Muscular Dystrophy $75 $75 $76 $78 $79 $81
Myasthenia Gravis $9 $7 $7 $8 $8 $8
Myotonic Dystrophy $9 $10 $10 $9 $9 $9
Nanotechnology 8/ $409 $456 $430 $409 $411 $421
Networking and Information Technology R&D 8/ $551 $532 $521 $612 $613 $628
Neuroblastoma $25 $34 $33 $37 $37 $39
Neurodegenerative $1,622 $1,671 $1,619 $1,743 $1,752 $1,788
Neurofibromatosis $23 $18 $17 $21 $21 $22
Neuropathy $146 $145 $151 $156 $157 $161
Neurosciences $5,548 $5,618 $5,340 $5,580 $5,634 $5,791
Nutrition $1,411 $1,692 $1,524 $1,555 $1,566 $1,600
Obesity $830 $836 $812 $857 $857 $878
Organ Transplantation $164 $150 $140 $142 $143 $144
Orphan Drug $749 $809 $764 $809 $813 $830
Osteogenesis Imperfecta $9 $9 $8 $11 $11 $12
Osteoporosis $179 $181 $164 $141 $142 $144
Otitis Media $15 $17 $14 $16 $16 $16
Ovarian Cancer $138 $147 $133 $131 $131 $135
Paget's Disease $1 $1 $0 $0 - -
Pain Conditions - Chronic $386 $396 $402 $402 $404 $414
Pain Research $0 $479 $475 $499 $501 $514
Pancreatic Cancer $112 $127 $125 $123 $123 $127
Parkinson's Disease $151 $154 $135 $139 $140 $144
Patient Safety $839 $845 $858 $1,008 $1,012 $1,035
Pediatric $3,277 $3,612 $3,266 $3,486 $3,523 $3,598
Pediatric AIDS 6/ $228 $219 $188 $166 $163 $168
Pediatric Cancer + + + $276 $277 $285
Pediatric Research Initiative $362 $379 $258 $343 $346 $353
Pelvic Inflammatory Disease $4 $3 $3 $2 $2 $2
Perinatal - Birth - Preterm (LBW) $214 $217 $198 $206 $207 $211
Perinatal - Neonatal Respiratory Distress Syndrome $37 $38 $33 $52 $53 $54
Perinatal Period - Conditions Originating in Perinatal Period $498 $538 $486 $534 $536 $549
Physical Rehabilitation + + + $113 $113 $116
Pick's Disease $3 $2 $3 $4 $4 $4
Pneumonia $117 $115 $113 $107 $107 $108
Pneumonia & Influenza $382 $358 $407 $362 $363 $384
Polycystic Kidney Disease $42 $42 $40 $36 $36 $37
Post-Traumatic Stress Disorder (PTSD) $0 $0 $77 $79 $79 $81
Prescription Drug Abuse $28 $33 $33 $40 $40 $41
Prevention $5,929 $5,924 $6,686 $6,858 $6,882 $7,005
Prostate Cancer $284 $257 $286 $254 $255 $262
Psoriasis $10 $10 $12 $13 $13 $13
Rare Diseases $3,527 $3,623 $3,456 $3,639 $3,654 $3,733
Regenerative Medicine $824 $877 $831 $836 $843 $862
Rehabilitation $459 $449 $446 $494 $496 $508
Rett Syndrome $12 $13 $13 $12 $12 $12
Reye's Syndrome $0 $0 $0 $0 - -
Rural Health $211 $231 $187 $197 $198 $203
Schizophrenia $264 $268 $232 $253 $255 $259
Scleroderma $25 $24 $21 $24 $24 $25
Screening And Brief Intervention For Substance Abuse $30 $31 $25 $30 $30 $31
Septicemia $91 $96 $88 $100 $100 $102
Serious Mental Illness + + + $407 $409 $415
Sexually Transmitted Diseases/Herpes $259 $275 $242 $263 $263 $267
Sickle Cell Disease $65 $65 $70 $75 $75 $77
Sleep Research $232 $238 $229 $233 $233 $239
Small Pox $41 $40 $30 $24 $24 $24
Smoking and Health $360 $353 $321 $320 $321 $330
Spina Bifida $11 $12 $10 $10 $10 $10
Spinal Cord Injury $78 $79 $94 $80 $81 $83
Spinal Muscular Atrophy $19 $15 $13 $16 $16 $16
Stem Cell Research $1,179 $1,374 $1,273 $1,391 $1,402 $1,436
Stem Cell Research - Embryonic - Human $123 $146 $146 $166 $168 $172
Stem Cell Research - Embryonic - Non-Human $165 $164 $154 $150 $152 $155
Stem Cell Research - Nonembryonic - Human $395 $504 $431 $443 $445 $457
Stem Cell Research - Nonembryonic - Non-Human $620 $653 $613 $627 $631 $646
Stem Cell Research - Umbilical Cord Blood/ Placenta $41 $47 $40 $34 $34 $35
Stem Cell Research - Umbilical Cord Blood/ Placenta - Human $36 $43 $35 $28 $28 $29
Stem Cell Research - Umbilical Cord Blood/ Placenta - Non-Human $10 $8 $7 $7 $7 $7
Stroke $317 $310 $282 $300 $302 $311
Substance Abuse 9/ $1,623 $1,634 $1,525 $1,564 $1,564 $1,611
Substance Abuse Prevention $44 $41 $65 $69 $69 $71
Sudden Infant Death Syndrome $23 $24 $20 $20 $21 $21
Suicide $49 $44 $37 $39 $39 $40
Suicide Prevention $25 $22 $21 $22 $22 $22
Teenage Pregnancy $19 $18 $17 $16 $16 $16
Temporomandibular Muscle/Joint Disorder (TMJD) $18 $21 $19 $18 $18 $18
Tobacco $362 $355 $322 $321 $322 $331
Topical Microbicides $104 $99 $93 $103 $103 $104
Tourette Syndrome $5 $6 $4 $4 $4 $4
Transmissible Spongiform Encephalopathy (TSE) $46 $39 $35 $33 $33 $34
Transplantation $592 $552 $538 $561 $565 $575
Tuberculosis $209 $218 $240 $279 $279 $285
Tuberculosis Vaccine $17 $21 $26 $31 $31 $31
Tuberous Sclerosis $20 $23 $20 $24 $24 $25
Underage Drinking $77 $80 $75 $83 $83 $85
Underage Drinking – Prevention & Treatment (NIAAA Only) 12/ $57 $62 $62 $59 $60 $61
Urologic Diseases $542 $496 $497 $494 $496 $509
Usher Syndrome + + + $19 $19 $19
Uterine Cancer $40 $42 $39 $57 $57 $59
Vaccine Related $1,717 $1,691 $1,608 $1,573 $1,576 $1,587
Vaccine related (AIDS) 6/ $550 $557 $518 $533 $537 $568
Valley Fever + + + $3 $4 $4
Vascular Cognitive Impairment/Dementia + + + $45 $45 $46
Vector-Borne Diseases $466 $441 $437 $487 $487 $492
Violence Against Women $34 $36 $31 $35 $36 $36
Violence Research $156 $154 $137 $130 $130 $134
Vulvodynia $2 $4 $4 $3 $3 $3
West Nile Virus $65 $29 $40 $48 $48 $48
Women's Health 5/ $3,891 $3,833 $3,745 $3,935 $3,936 $3,946
Youth Violence $87 $77 $70 $59 $59 $60
Youth Violence Prevention $26 $27 $26 $16 $16 $17
[*] The minimum reporting threshold for a specific disease/condition is $500,000. Reporting of $0 does not indicate that no research is being conducted.
[+] Indicates a new category. Funding support data not available prior to the initial year reported.
1/ Reporting for this category does not follow the standard RCDC process. The total amount reported is consistent with reporting requirements for this category to the U.S. Office of Management & Budget (OMB). The project listing does not include non-project or other support costs associated with the annual total for this category. Additional information on this category is available at http://www.niaid.nih.gov/topics/biodefenserelated/pages/default.aspx.
2/ Includes research funded from the Type 1 diabetes appropriation. These are project listings only.
3/ Reporting for this category does not follow the standard RCDC process. Spending for this category is reported consistent with U.S. Office of National Drug Control Policy (ONDCP) requirements. This category includes only projects funded by NIDA. More information on this area is available at http://www.drugabuse.gov/drugs-abuse. FY 2014 actual and FY 2015 estimate reported in RePORT can differ from levels identified in the FY 2016 Drug Control budget submission for those fiscal years where comparable adjustments have been applied.
4/ Reported total for this category encompasses research for anorexia, bulimia nervosa, binge eating disorders, and eating disorders not otherwise specified.
5/ Reporting for this category does not follow the standard RCDC process. This category assigns project funding according to populations tracked by gender or ethnicity. The databases used to track gender/ethnicity are complex are not currently compatible with the RCDC system.
6/ The total for AIDS research includes both extramural and intramural research (including research management and support, Management Fund, and Service & Supply Fund), buildings and facilities, research training, and program evaluation, as well as research on the many HIV-associated co-infections and co-morbidities, including TB, hepatitis C, and HIV-associated cancers. It also includes all of the basic science underlying this research. Other RCDC categories are not reported this way; thus the total for AIDS-related research is not comparable to spending reported for other RCDC diseases. More information on this area is available at http://www.oar.nih.gov/hivaids/.
7/ Reporting for this category does not follow the standard RCDC process. This category uses a non-standard approach involving subject matter expert reviews of manually collected project listings.
8/ The data provided reflects funding amounts reported by the NIH RCDC process for this category. Actual and estimate levels presented on this site supersede estimates detailed in OMB MAX DE application tables that may have been based on preliminary funding support information.
9/ Reporting for this category does not follow the standard RCDC process. This category includes all spending reported under the Drug Abuse category as well as projects categorized under the broader area of Substance Abuse. These are project listings only. More information on this area is available at http://www.drugabuse.gov/drugs-abuse.
10/ Prior to FY 2011, this category's title was "Health Effects of Climate Change". The title was revised to more accurately reflect the content of the research conducted and facilitate reporting spending data in response to requests tracking climate change adaptation.
11/ Name revised in FY 2013 to reflect current scientific terminology.
12/ Reporting for this category does not follow the standard RCDC process. Spending for this category is reported consistent with U.S. Office of National Drug Control Policy (ONDCP) requirements. This category includes only projects funded or administered by NIAAA. This category represents a subset of spending reported under the RCDC Underage Drinking category and involves manual review of the project listing by subject matter experts. More information on this area is available at http://www.niaaa.nih.gov/research/major-initiatives/underage-drinking-research-initiative.

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