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Christopher Lock
Multiple sclerosis specialist
Clinical Associate Professor, Neurology & Neurological Sciences
Practice Areas
Professional Education
- Fellowship: Stanford University School of Medicine (2000) CA
- Board Certification: Neurology, American Board of Psychiatry and Neurology (1999)
- Residency: Stanford University School of Medicine (1997) CA
- Internship: Stanford University School of Medicine (1994) CA
- Medical Education: Westminster Medical School (1980) England
Publications
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Janus-like opposing roles of CD47 in autoimmune brain inflammation in humans and mice
Han, M. H., Lundgren, D. H., Jaiswal, S., Chao, M., Graham, K. L., & Steinman, L. (2012). Janus-like opposing roles of CD47 in autoimmune brain inflammation in humans and mice. JOURNAL OF EXPERIMENTAL MEDICINE, 209(7), 1325-1334. -
Inhibitory role for GABA in autoimmune inflammation
Bhat, R., Axtell, R., Mitra, A., Miranda, M., Lock, C., & Steinman, L. (2010). Inhibitory role for GABA in autoimmune inflammation. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 107(6), 2580-2585. -
Gene-microarray analysis of multiple sclerosis lesions yields new targets validated in autoimmune encephalomyelitis
Lock, C., Hermans, G., Pedotti, R., Brendolan, A., Schadt, E., & Steinman, L. (2002). Gene-microarray analysis of multiple sclerosis lesions yields new targets validated in autoimmune encephalomyelitis. NATURE MEDICINE, 8(5), 500-508. -
The influence of the proinflammatory cytokine, osteopontin, on autoimmune demyelinating disease
Chabas, D., Baranzini, S. E., Mitchell, D., Bernard, C. Ca., Rittling, S. R., & Steinman, L. (2001). The influence of the proinflammatory cytokine, osteopontin, on autoimmune demyelinating disease. SCIENCE, 294(5547), 1731-1735.
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The role of TNF alpha and lymphotoxin in demyelinating disease
Lock, C., Oksenberg, J., & Steinman, L. (1999). The role of TNF alpha and lymphotoxin in demyelinating disease. ANNALS OF THE RHEUMATIC DISEASES, 58, 121-128.
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The role of TNFalpha and lymphotoxin in demyelinating disease.
Lock, C., Oksenberg, J., & Steinman, L. (1999). The role of TNFalpha and lymphotoxin in demyelinating disease. Annals of the rheumatic diseases, 58, I121-8.
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EXPRESSION OF HLA-DR4 AND HUMAN CD4 TRANSGENES IN MICE DETERMINES THE VARIABLE REGION BETA-CHAIN T-CELL REPERTOIRE AND MEDIATES AN HLA-DR-RESTRICTED IMMUNE-RESPONSE
Fugger, L., Michie, S. A., Rulifson, I., Lock, C. B., & McDevitt, G. S. (1994). EXPRESSION OF HLA-DR4 AND HUMAN CD4 TRANSGENES IN MICE DETERMINES THE VARIABLE REGION BETA-CHAIN T-CELL REPERTOIRE AND MEDIATES AN HLA-DR-RESTRICTED IMMUNE-RESPONSE. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 91(13), 6151-6155.
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MINIMUM STRUCTURAL REQUIREMENTS FOR PEPTIDE PRESENTATION BY MAJOR HISTOCOMPATIBILITY COMPLEX CLASS-II MOLECULES - IMPLICATIONS IN INDUCTION OF AUTOIMMUNITY
Gautam, A. M., Lock, C. B., Smilek, D. E., Pearson, C. I., Steinman, L., & McDevitt, H. O. (1994). MINIMUM STRUCTURAL REQUIREMENTS FOR PEPTIDE PRESENTATION BY MAJOR HISTOCOMPATIBILITY COMPLEX CLASS-II MOLECULES - IMPLICATIONS IN INDUCTION OF AUTOIMMUNITY. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 91(2), 767-771.
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ANTIGEN RECOGNITION AND PEPTIDE-MEDIATED IMMUNOTHERAPY IN AUTOIMMUNE-DISEASE
Smilek, D. E., Lock, C. B., & McDevitt, H. O. (1990). ANTIGEN RECOGNITION AND PEPTIDE-MEDIATED IMMUNOTHERAPY IN AUTOIMMUNE-DISEASE. IMMUNOLOGICAL REVIEWS, 118, 37-71.
Patient Comments
Patients comments are gathered from our Patient Satisfaction Survey and displayed in their entirety. Patients are de-identified for confidentiality and patient privacy.