A rush to judgment on Th17 JOURNAL OF EXPERIMENTAL MEDICINE Steinman, L. 2008; 205 (7): 1517-1522

Abstract

Some immunologists have characterized T helper (Th)17 T cells as the master mediators of tissue damage in a variety of pathological conditions. New data now demonstrate that Th1 and Th17 T cells are independently capable of inducing disease in two established models of autoimmunity. Thus, the role of Th17 cytokines as the central mediators of pathological tissue damage seems to require clarification.

View details for DOI 10.1084/jem.20072066

View details for Web of Science ID 000258527000002

View details for PubMedID 18591407