Tools for capturing the functional state of a cell or collection of cells have advanced rapidly in the last decade. Prominent among these are a variety of DNA microarray technologies. We intend to provide a facility whereby Stanford medical and other researchers have easy access to the most advanced functional genomic technologies at nominal cost.
Researchers will be able to access the facility at a number of levels. At the highest service level, clinical researchers can submit tissue and have results on the relative expression or protein level functional state of the sample returned to them. If more control is desired, the researcher can join in the process at any number of points, all the way down to collaborating with the facility on protocol and instrumentation development.
Description of Services
The Stanford Functional Genomics Facility (SFGF) provides microarrays and microarray services to researchers within the Stanford community and beyond. The facility also provides 24/7 access to instruments, equipment, and software utilized within the microarray field. We support all arrays based on a microscope slide format including Agilent, Illumina, Nimblegen, and arrays produced by SFGF. Besides printing cDNA and oligonucliotide microarrays, the facility can also print arrays of your material in a high throughput fashion, including proteins, peptides, antibodies, cell lysates, siRNAs, etc.
Selected References
The essential genome of a bacterium. Christen B, Abeliuk E, Collier JM, Kalogeraki VS, Passarelli B, Coller JA, Fero MJ, McAdams HH, Shapiro L. Mol Syst Biol. 2011 Aug 30;7:528. PubMedID: 21878915.
Single-molecule sequencing of an individual human genome. Pushkarev D, Neff NF, Quake SR. Nat. Biotechnol. 2009 Sep;27(9):847-50. Epub 2009 Aug 10. PubMedID: 19668243.
Direct lineage conversion of terminally differentiated hepatocytes to functional neurons. Marro S, Pang ZP, Yang N, Tsai MC, Qu K, Chang HY, Südhof TC, Wernig M. Cell Stem Cell. 2011 Oct 4;9(4):374-82. PubMedID: 21962918.
