Contents
01 December 2017
Vol 358, Issue 6367
Vol 358, Issue 6367
Contents
This Week in Science
Editorial
Editors' Choice
Products & Materials
- New Products
A weekly roundup of information on newly offered instrumentation, apparatus, and laboratory materials of potential interest to researchers.
In Brief
In Depth
- Boston University geologist fights for his job
Marchant appeals finding that he sexually harassed grad student in Antarctica 18 years ago
- Political chill reverses thaw in U.S.-Cuban science
Blows to research collaborations are collateral damage of the Trump administration's moves to cool relations
- Poachers threaten Balkans' underground biodiversity
Scientists sound the alarm after finding hundreds of illegal traps in caves in three countries
- Relativity survives drop test
Satellite tightens measurements of equivalence principle
- Automatic error spotter gains in popularity
Algorithm that checks statistics in papers is highly accurate, its developers say
- A wet blanket for theories of liquid water on Mars
The mystery of dark streaks endures for Alfred McEwen
Feature
- Ice on the run
Scientists are unraveling why certain glaciers are prone to surging abruptly—sometimes wiping out people in their path
Working Life
Letters
Books et al.
- To frack or not to frack
A straightforward guide offers a nuanced look at unconventional fossil fuel extraction
Policy Forum
- Insurance for broad genomic tests in oncology
Insurance coverage should precede rather than follow clinical validation of broad genomic testing in oncology
- Principles for gene drive research
Sponsors and supporters of gene drive research respond to a National Academies report
Perspectives
- How pterosaurs bred
Hundreds of fossil eggs elucidate embryo development and nesting behaviors of pterosaurs
- Escaping the traps of your own hunters
Cleavage of extracellular DNA NETs is essential for inhibiting peripheral organ failure
- Bone voyage—Osteoblasts remotely control tumors
Tumor-driven systemic activation of osteoblasts in the bone promotes lung tumor growth
- Navigating in a sea of genes
Randomly generated microbial genomes produce realistic nutrient gradients in a model ocean
- Obesity and the tumor microenvironment
Obesity-associated inflammation promotes tumor growth and metastatic spread
- Benzene submits to main-group power
Calcium hydride reagents allow benzene to react with electron-rich reagents
Research Articles
- The target landscape of clinical kinase drugs
The druggable kinome is unraveled.
- Osteoblasts remotely supply lung tumors with cancer-promoting SiglecFhigh neutrophils
Systemic cross-talk between tumor and bone can boost the growth of early-stage lung cancer in mice.
- Ocean biogeochemistry modeled with emergent trait-based genomics
Results of genomic-based microbe community modeling resemble real-world observations from the Amazon River plume.
- Stripe order in the underdoped region of the two-dimensional Hubbard model
Multiple numerical methods are used to study the ground-state and finite-temperature solutions of the Hubbard model.
Review
Reports
- Numerical evidence of fluctuating stripes in the normal state of high-Tc cuprate superconductors
Multiple numerical methods are used to study the ground-state and finite-temperature solutions of the Hubbard model.
- Observations and modeling of the elastogravity signals preceding direct seismic waves
The observation of elastogravity signals provides a much faster method for determining the size of great earthquakes.
- Organocalcium-mediated nucleophilic alkylation of benzene
Alkyl calcium compounds can forge a carbon-carbon bond with benzene by displacing a hydride.
- The image-forming mirror in the eye of the scallop
The crystal morphology, organization, and three-dimensional shape of the scallop eye mirror are finely controlled for image formation.
- Spectroscopic signatures of localization with interacting photons in superconducting qubits
A many-body spectroscopy technique based on a chain of superconducting qubits gives insight into the localization transition.
- Giant nonlinear response at a plasmonic nanofocus drives efficient four-wave mixing
Efficient wave mixing in plasmonic waveguides provides a versatile platform for compact nonlinear optical devices.
- Photoredox-catalyzed deuteration and tritiation of pharmaceutical compounds
A light-promoted atom transfer protocol uses heavy water to isotopically label alkyl sites for drug metabolism studies.
- Selective increase in CO2 electroreduction activity at grain-boundary surface terminations
Grain-boundary surface terminations of a gold film increase the activity of CO2 electroreduction but not H2 evolution.
- A generic interface to reduce the efficiency-stability-cost gap of perovskite solar cells
Tantalum-doped tungsten oxide forms nearly ohmic contacts with conjugated polymers to create efficient hole transporters.
- Egg accumulation with 3D embryos provides insight into the life history of a pterosaur
Possible pterosaur rookery reveals secrets of embryo development.
- Host DNases prevent vascular occlusion by neutrophil extracellular traps
Deoxyribonucleases work together to control vascular occlusion by neutrophil-induced blood clots.
- 3.9 Å structure of the yeast Mec1-Ddc2 complex, a homolog of human ATR-ATRIP
The cryo–electron microscopy structure of a DNA damage sensor complex reveals detailed architecture and regulatory mechanism.
Technical Comments
About The Cover
COVER Wahlenbergbreen glacier in Svalbard, Norway, is seen in September 2013, as its flow began speeding up. At the peak of the surge, beginning in 2015, the ice advanced at 9 meters per day, bulldozing everything in its path. A glacier’s shape, the nature of its bed, and climate change can interact to trigger normally quiescent glaciers to surge. See page 1120.
Photo: Heïdi Sevestre