Clinical Research
Ophthalmology Clinical Trials
Center for Clinical Study of Vitreoretinal Disease
California Vitreoretinal Center
Investigators active at CVRC include: Mark S. Blumenkranz, M.D., Robert Jack, M.D., Thomas Rice, M.D., Steve Sanislo, M.D., and Darius Moshfeghi, M.D., Ted Leng, M.D., Ruwan Silva, M.D., Peter Karth, M.D.
A clinical research unit with multiple full-time research coordinators and special instrumentation designed to study the normal retina as well as various disease states and experimental therapies. The Center works in close collaboration with the University, including Medicine, Surgery, Physics and Pathology, and multiple leading-edge medical instrument and biotechnology companies including Coherent Laser, Iridex Laser, Zeiss Humphrey Instruments, Alcon Laboratories, Genentech, Agouron Pharmaceuticals, Pharmacyclics and Eli Lilly.
In recent years, the Center has been at the forefront of important advances in photodynamic therapy for age-related macular degeneration (ARMD), in the use of lasers and other novel treatment regimes for the early stages of ARMD and in the use of liquid perfluorocarbons and silicone oil for retinal detachment.
Center for Clinical Electrophysiology of the Retina
Principal Investigator: Michael F. Marmor, M.D.
Explorations of new techniques in electroretinography and related tests, and the electrophysiologic characterization of mechanisms and diagnosis of retinal disease. Investigations include studies on multifocal electroretinography, recognition of S-cone responses, and non-photic responses of the retinal pigment epithelium, as well as clinical studies on central serous chorioretinopathy, hydroxychloroquine toxicity, retinal dystrophies and age-related macular degeneration.
Center for the Clinical Study of Cornea and External Diseases
Principal Investigator: Christopher N. Ta, M.D.
These studies are made possible through generous donations by:
- The Hills Foundation
- Allergan Pharmaceuticals
- The Georg and Hannalore Zimmerman Foundation
Clinical Studies at the Stanford Eye Center include:
- Dry-Eyes in Graft-versus-host Disease
We are currently enrolling patients in a prospective observation study to determine the prognosis and treatment outcome of patients with dry eyes secondary to graft-versus-host disease. - Efficacy study of Zymar and Vigamox
We are currently enrolling patients in a prospective randomized study to determine the effectiveness of two commonly prescribed topical antibiotics: Zymar and Vigamox. - Intravitreous Injections
We are currently enrolling patients in a prospective study to determine ways to determine the role of topical antibiotics in patients undergoing intravitreal injections.