Xp11 / TFE3 Translocation Carcinoma of the Kidney
Clinical
- Mean age reported about 25
- Most studies have focused on renal tumors arising in young people
- Has been reported at all ages
- Clearly has been under-recognized in the past in adults
- Behavior uncertain
- Frequently presents with metastases
- Initial reports suggested relatively indolent behavior
- Later reports describe more aggressive behavior, especially in adults
- A few cases have been reported following chemotherapy for other processes